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Optimization of an analytical procedure for the determination of banned azo dyes in leather

Ahlström, Lars-Henric LU ; Björklund, Erland LU and Mathiasson, Lennart LU (2005) In Analytical and Bioanalytical Chemistry 382(5). p.1320-1327
Abstract
The possibility of improving an existing method, based on supercritical-fluid extraction (SFE) and microwave-assisted extraction (MAE), for the determination of banned azo dyes in leather has been studied. Thus, optimization of experimental conditions in different steps (degreasing, reduction, and extraction) of the analytical procedure was performed. The influence of different variables (reaction time, temperature, and concentration of reducing agent) on the reduction process was evaluated by use of a factorial design. It was found that the concentration of the reducing agent and the interaction between time and temperature were the most influential variables. Consequently, by applying a higher temperature, the reaction time could be... (More)
The possibility of improving an existing method, based on supercritical-fluid extraction (SFE) and microwave-assisted extraction (MAE), for the determination of banned azo dyes in leather has been studied. Thus, optimization of experimental conditions in different steps (degreasing, reduction, and extraction) of the analytical procedure was performed. The influence of different variables (reaction time, temperature, and concentration of reducing agent) on the reduction process was evaluated by use of a factorial design. It was found that the concentration of the reducing agent and the interaction between time and temperature were the most influential variables. Consequently, by applying a higher temperature, the reaction time could be halved. The use of acidified water as extraction solvent in MAE was also investigated. Usually 1 mol L-1 HCl was superior to methanol and buffer in terms of extraction efficiency. In conclusion, the present method gave significantly higher recoveries in comparison with the original method. All dyes were determined indirectly by measuring their corresponding harmful amines, formed after reduction by use of sodium dithionite. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Analytical and Bioanalytical Chemistry
volume
382
issue
5
pages
1320 - 1327
publisher
Springer
external identifiers
  • wos:000230316000019
  • scopus:22144484484
ISSN
1618-2642
DOI
10.1007/s00216-005-3240-2
language
English
LU publication?
yes
id
7f1d3530-8f3a-42ac-bbed-0338cd439273 (old id 150995)
date added to LUP
2007-06-25 17:00:56
date last changed
2017-05-07 03:29:48
@article{7f1d3530-8f3a-42ac-bbed-0338cd439273,
  abstract     = {The possibility of improving an existing method, based on supercritical-fluid extraction (SFE) and microwave-assisted extraction (MAE), for the determination of banned azo dyes in leather has been studied. Thus, optimization of experimental conditions in different steps (degreasing, reduction, and extraction) of the analytical procedure was performed. The influence of different variables (reaction time, temperature, and concentration of reducing agent) on the reduction process was evaluated by use of a factorial design. It was found that the concentration of the reducing agent and the interaction between time and temperature were the most influential variables. Consequently, by applying a higher temperature, the reaction time could be halved. The use of acidified water as extraction solvent in MAE was also investigated. Usually 1 mol L-1 HCl was superior to methanol and buffer in terms of extraction efficiency. In conclusion, the present method gave significantly higher recoveries in comparison with the original method. All dyes were determined indirectly by measuring their corresponding harmful amines, formed after reduction by use of sodium dithionite.},
  author       = {Ahlström, Lars-Henric and Björklund, Erland and Mathiasson, Lennart},
  issn         = {1618-2642},
  language     = {eng},
  number       = {5},
  pages        = {1320--1327},
  publisher    = {Springer},
  series       = {Analytical and Bioanalytical Chemistry},
  title        = {Optimization of an analytical procedure for the determination of banned azo dyes in leather},
  url          = {http://dx.doi.org/10.1007/s00216-005-3240-2},
  volume       = {382},
  year         = {2005},
}