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Magnetization transfer (MT) of human brain at 7T in the context of a 3D multi-parameter mapping protocol

Olsson, Hampus LU ; Andersen, Mads LU ; Lätt, Jimmy LU ; Wirestam, Ronnie LU orcid and Helms, Gunther LU orcid (2019) ISMRM 27th Annual Meeting and Exhibition In Proc Intl Soc Magn Reson Med 27.
Abstract
3D multi-gradient echo MRI can be used to estimate T1, T2*, PD and the magnetization transfer (MT), which is increasingly used for multi-parametric
mapping (MPM) of human brain. The increased polarization at 7T compared to lower B0 allows for increased spatial resolution or reduced scan
times. However, SAR restrictions imposed on the MT pulse and B1 inhomogeneity pose challenges. In this work, we propose a protocol for MPM of
human brain at 7T with special attention paid to eliminating bias when mapping MT saturation while obtaining sub-millimeter isotropic spatial resolution in
under 12 minutes with acceptable SNR.
Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
Magnetization transfer (MT) of human brain at 7T in the context of a 3D multi-parameter mapping protocol
series title
Proc Intl Soc Magn Reson Med
volume
27
article number
309
pages
4 pages
publisher
International Society for Magnetic Resonance in Medicine
conference name
ISMRM 27th Annual Meeting and Exhibition
conference location
Montreal, Canada
conference dates
2019-05-11 - 2019-05-16
ISSN
1545-4428
project
Multiparametric mapping of the brain at 7T using gradient echoes
language
English
LU publication?
yes
id
150abbde-3d98-4f9b-a964-80437c9117ab
alternative location
https://index.mirasmart.com/ISMRM2019/PDFfiles/0309.html
date added to LUP
2019-05-30 09:49:39
date last changed
2021-05-19 15:52:00
@inproceedings{150abbde-3d98-4f9b-a964-80437c9117ab,
  abstract     = {{3D multi-gradient echo MRI can be used to estimate T1, T2*, PD and the magnetization transfer (MT), which is increasingly used for multi-parametric<br/>mapping (MPM) of human brain. The increased polarization at 7T compared to lower B0 allows for increased spatial resolution or reduced scan<br/>times. However, SAR restrictions imposed on the MT pulse and B1 inhomogeneity pose challenges. In this work, we propose a protocol for MPM of<br/>human brain at 7T with special attention paid to eliminating bias when mapping MT saturation while obtaining sub-millimeter isotropic spatial resolution in<br/>under 12 minutes with acceptable SNR.<br/>}},
  author       = {{Olsson, Hampus and Andersen, Mads and Lätt, Jimmy and Wirestam, Ronnie and Helms, Gunther}},
  booktitle    = {{Magnetization transfer (MT) of human brain at 7T in the context of a 3D multi-parameter mapping protocol}},
  issn         = {{1545-4428}},
  language     = {{eng}},
  month        = {{04}},
  publisher    = {{International Society for Magnetic Resonance in Medicine}},
  series       = {{Proc Intl Soc Magn Reson Med}},
  title        = {{Magnetization transfer (MT) of human brain at 7T in the context of a 3D multi-parameter mapping protocol}},
  url          = {{https://index.mirasmart.com/ISMRM2019/PDFfiles/0309.html}},
  volume       = {{27}},
  year         = {{2019}},
}