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Osteotomy of distal radius fracture malunion using a fast remodeling bone substitute consisting of calcium sulphate and calcium phosphate.

Abramo, Antonio LU ; Geijer, Mats LU ; Kopylov, Philippe LU and Tägil, Magnus LU (2010) In Journal of Biomedical Materials Research. Part B - Applied Biomaterials 92B. p.281-286
Abstract
Malunion after a distal radius fracture can be treated with an osteotomy of the distal radius. Autologous iliac crest bone graft is often used to fill the gap, but the procedure is associated with donor site morbidity. In this study a novel fast resorbing biphasic bone substitute consisting of a mixture of calcium sulphate and calcium phosphate is used (Cerament BoneSupport AB, Sweden). Fifteen consecutive patients, with a mean age of 52 (27-71) years were included. All had a malunion after a distal radius fracture and underwent an osteotomy. A fragment specific fixation system, TriMed(R) (TriMed, Valencia, CA), consisting of a Buttress Pin(R) and a Radial Pin Plate(R) were used for fixation and a calcium sulphate and calcium phosphate... (More)
Malunion after a distal radius fracture can be treated with an osteotomy of the distal radius. Autologous iliac crest bone graft is often used to fill the gap, but the procedure is associated with donor site morbidity. In this study a novel fast resorbing biphasic bone substitute consisting of a mixture of calcium sulphate and calcium phosphate is used (Cerament BoneSupport AB, Sweden). Fifteen consecutive patients, with a mean age of 52 (27-71) years were included. All had a malunion after a distal radius fracture and underwent an osteotomy. A fragment specific fixation system, TriMed(R) (TriMed, Valencia, CA), consisting of a Buttress Pin(R) and a Radial Pin Plate(R) were used for fixation and a calcium sulphate and calcium phosphate mixture as bone substitute. The patients were followed for 1 year. Grip strength increased from 61 (28-93)% of the contralateral hand to 85 (58-109)%, p < 0.001. DASH scores decreased from 37 (22-61) to 24 (2-49) p = 0.003. Radiographically all osteotomies healed. An increase of ulnar variance was noted during healing from 1.8 mm immediately postoperatively to 2.6 mm at final follow up. Osteotomy can increase grip strength and decease disability after a malunited fracture. In the present series the bone substitute was replaced by bone, but a minor loss of the achieved radiographic correction was noted in some patients during osteotomy healing. A more rigid fixation may improve the radiographic outcome with this kind of bone substitute. (c) 2009 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2010. (Less)
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organization
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type
Contribution to journal
publication status
published
subject
in
Journal of Biomedical Materials Research. Part B - Applied Biomaterials
volume
92B
pages
281 - 286
publisher
John Wiley & Sons
external identifiers
  • wos:000272896500033
  • pmid:19904822
  • scopus:74749097462
ISSN
1552-4981
DOI
10.1002/jbm.b.31524
language
English
LU publication?
yes
id
27a8def6-4f0f-4eb6-81f7-46c25fc1e19b (old id 1512056)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19904822?dopt=Abstract
date added to LUP
2009-12-01 14:08:15
date last changed
2018-06-17 04:56:56
@article{27a8def6-4f0f-4eb6-81f7-46c25fc1e19b,
  abstract     = {Malunion after a distal radius fracture can be treated with an osteotomy of the distal radius. Autologous iliac crest bone graft is often used to fill the gap, but the procedure is associated with donor site morbidity. In this study a novel fast resorbing biphasic bone substitute consisting of a mixture of calcium sulphate and calcium phosphate is used (Cerament BoneSupport AB, Sweden). Fifteen consecutive patients, with a mean age of 52 (27-71) years were included. All had a malunion after a distal radius fracture and underwent an osteotomy. A fragment specific fixation system, TriMed(R) (TriMed, Valencia, CA), consisting of a Buttress Pin(R) and a Radial Pin Plate(R) were used for fixation and a calcium sulphate and calcium phosphate mixture as bone substitute. The patients were followed for 1 year. Grip strength increased from 61 (28-93)% of the contralateral hand to 85 (58-109)%, p &lt; 0.001. DASH scores decreased from 37 (22-61) to 24 (2-49) p = 0.003. Radiographically all osteotomies healed. An increase of ulnar variance was noted during healing from 1.8 mm immediately postoperatively to 2.6 mm at final follow up. Osteotomy can increase grip strength and decease disability after a malunited fracture. In the present series the bone substitute was replaced by bone, but a minor loss of the achieved radiographic correction was noted in some patients during osteotomy healing. A more rigid fixation may improve the radiographic outcome with this kind of bone substitute. (c) 2009 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2010.},
  author       = {Abramo, Antonio and Geijer, Mats and Kopylov, Philippe and Tägil, Magnus},
  issn         = {1552-4981},
  language     = {eng},
  pages        = {281--286},
  publisher    = {John Wiley & Sons},
  series       = {Journal of Biomedical Materials Research. Part B - Applied Biomaterials},
  title        = {Osteotomy of distal radius fracture malunion using a fast remodeling bone substitute consisting of calcium sulphate and calcium phosphate.},
  url          = {http://dx.doi.org/10.1002/jbm.b.31524},
  volume       = {92B},
  year         = {2010},
}