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Separation of amino acids, peptides and proteins on molecularly imprinted stationary phases.

Kempe, Maria LU and Mosbach, Klaus LU (1995) In Journal of Chromatography A 691(1-2). p.317-323
Abstract
Stationary phases, to be used in high-performance liquid chromatography, were tailor-made for the separation of amino acids, peptides and proteins. The stationary phases were prepared by molecular imprinting, applying two different approaches. Low-molecular-mass compounds were imprinted in bulk polymers by copolymerization of functional monomers and cross-linkers in the presence of the compound of interest, the print molecule. These polymers were, after extraction of the print molecule, successfully applied as chiral stationary phases, showing high resolution and load capacity. The development of a surface-imprinting approach for the preparation of stationary phases selective for proteins is also discussed.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Chromatography A
volume
691
issue
1-2
pages
317 - 323
publisher
Elsevier
external identifiers
  • scopus:0028896946
ISSN
0021-9673
DOI
10.1016/0021-9673(94)00820-Y
language
English
LU publication?
yes
id
f7f265ab-d1e9-466e-8401-dbae91952230 (old id 1516067)
date added to LUP
2009-12-17 09:06:37
date last changed
2017-08-13 04:26:58
@article{f7f265ab-d1e9-466e-8401-dbae91952230,
  abstract     = {Stationary phases, to be used in high-performance liquid chromatography, were tailor-made for the separation of amino acids, peptides and proteins. The stationary phases were prepared by molecular imprinting, applying two different approaches. Low-molecular-mass compounds were imprinted in bulk polymers by copolymerization of functional monomers and cross-linkers in the presence of the compound of interest, the print molecule. These polymers were, after extraction of the print molecule, successfully applied as chiral stationary phases, showing high resolution and load capacity. The development of a surface-imprinting approach for the preparation of stationary phases selective for proteins is also discussed.},
  author       = {Kempe, Maria and Mosbach, Klaus},
  issn         = {0021-9673},
  language     = {eng},
  number       = {1-2},
  pages        = {317--323},
  publisher    = {Elsevier},
  series       = {Journal of Chromatography A},
  title        = {Separation of amino acids, peptides and proteins on molecularly imprinted stationary phases.},
  url          = {http://dx.doi.org/10.1016/0021-9673(94)00820-Y},
  volume       = {691},
  year         = {1995},
}