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Receptor binding mimetics: a novel molecularly imprinted polymer

Kempe, Maria LU and Mosbach, Klaus LU (1995) In Tetrahedron Letters 36(20). p.3563-3566
Abstract
A novel molecularly imprinted polymer was prepared by copolymerization of trimethylolpropane trimethacrylate (1) and methacrylic acid (3) in the presence of a dipeptide acting as the template. The recognition capability of the synthetic receptor-like binding sites produced in the polymer network for the peptide was demonstrated by using the polymer as a chiral stationary phase in HPLC. The polymer was superior to previously reported molecularly imprinted polymers in that unusually high racemic resolution and load capacity were demonstrated.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Tetrahedron Letters
volume
36
issue
20
pages
3563 - 3566
publisher
Elsevier
external identifiers
  • scopus:0029024451
ISSN
0040-4039
DOI
10.1016/0040-4039(95)00559-U
language
English
LU publication?
yes
id
3b6fd1b7-a7ea-48bf-86a3-bff0008fe1a1 (old id 1516080)
date added to LUP
2009-12-17 09:17:47
date last changed
2017-04-24 17:11:21
@article{3b6fd1b7-a7ea-48bf-86a3-bff0008fe1a1,
  abstract     = {A novel molecularly imprinted polymer was prepared by copolymerization of trimethylolpropane trimethacrylate (1) and methacrylic acid (3) in the presence of a dipeptide acting as the template. The recognition capability of the synthetic receptor-like binding sites produced in the polymer network for the peptide was demonstrated by using the polymer as a chiral stationary phase in HPLC. The polymer was superior to previously reported molecularly imprinted polymers in that unusually high racemic resolution and load capacity were demonstrated.},
  author       = {Kempe, Maria and Mosbach, Klaus},
  issn         = {0040-4039},
  language     = {eng},
  number       = {20},
  pages        = {3563--3566},
  publisher    = {Elsevier},
  series       = {Tetrahedron Letters},
  title        = {Receptor binding mimetics: a novel molecularly imprinted polymer},
  url          = {http://dx.doi.org/10.1016/0040-4039(95)00559-U},
  volume       = {36},
  year         = {1995},
}