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2-Bromoethyl glycosides for synthesis of glycoconjugates on solid support

Ellervik, Ulf LU ; Jacobsson, Mårten LU and Ohlsson, Jörgen LU (2005) In Tetrahedron 61(9). p.2421-2429
Abstract
2-Bromoethyl glycosides can easily and in high yields be transformed into sulfones by treatment with a suitable thiol followed by oxidation with mCPBA. The observation that the so formed sulfones were cleaved by treatment with NaOMe/MeOH was used to design a new safety catch linker for synthesis of glycoconjugates on solid support. (C) 2005 Elsevier Ltd. All rights reserved.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Tetrahedron
volume
61
issue
9
pages
2421 - 2429
publisher
Elsevier
external identifiers
  • wos:000227267300019
  • scopus:13644259121
ISSN
0040-4020
DOI
10.1016/j.tet.2005.01.015
language
English
LU publication?
yes
id
e8791a2a-20dd-41c8-94c7-5b049bd566a8 (old id 152428)
date added to LUP
2007-07-10 09:40:15
date last changed
2017-01-01 07:04:53
@article{e8791a2a-20dd-41c8-94c7-5b049bd566a8,
  abstract     = {2-Bromoethyl glycosides can easily and in high yields be transformed into sulfones by treatment with a suitable thiol followed by oxidation with mCPBA. The observation that the so formed sulfones were cleaved by treatment with NaOMe/MeOH was used to design a new safety catch linker for synthesis of glycoconjugates on solid support. (C) 2005 Elsevier Ltd. All rights reserved.},
  author       = {Ellervik, Ulf and Jacobsson, Mårten and Ohlsson, Jörgen},
  issn         = {0040-4020},
  language     = {eng},
  number       = {9},
  pages        = {2421--2429},
  publisher    = {Elsevier},
  series       = {Tetrahedron},
  title        = {2-Bromoethyl glycosides for synthesis of glycoconjugates on solid support},
  url          = {http://dx.doi.org/10.1016/j.tet.2005.01.015},
  volume       = {61},
  year         = {2005},
}