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Spare respiratory capacity, oxidative stress and excitotoxicity

Nicholls, David LU (2009) In Biochemical Society Transactions 37. p.1385-1388
Abstract
Chronic exposure to glutamate (glutamate excitotoxicity) exacerbates neuronal damage in the aftermath of stroke and is implicated in a variety of neurodegenerative disorders. mitochondria play a central role in the survival or death of the exposed neuron. calcium, oxidative stress and ATP insufficiency play closely interlocked roles that may be investigated with primary neuronal cultures.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
oxidative, mitochondrion, ischaemia, glutamate, ATP, excitotoxicity, stress
in
Biochemical Society Transactions
volume
37
pages
1385 - 1388
publisher
Biochemical Society
external identifiers
  • wos:000272646000044
  • scopus:70450207200
ISSN
0300-5127
DOI
10.1042/BST0371385
language
English
LU publication?
yes
id
9dbe850f-174a-47d3-90ea-040568062a0a (old id 1532915)
date added to LUP
2010-01-28 17:07:49
date last changed
2017-10-22 03:38:12
@article{9dbe850f-174a-47d3-90ea-040568062a0a,
  abstract     = {Chronic exposure to glutamate (glutamate excitotoxicity) exacerbates neuronal damage in the aftermath of stroke and is implicated in a variety of neurodegenerative disorders. mitochondria play a central role in the survival or death of the exposed neuron. calcium, oxidative stress and ATP insufficiency play closely interlocked roles that may be investigated with primary neuronal cultures.},
  author       = {Nicholls, David},
  issn         = {0300-5127},
  keyword      = {oxidative,mitochondrion,ischaemia,glutamate,ATP,excitotoxicity,stress},
  language     = {eng},
  pages        = {1385--1388},
  publisher    = {Biochemical Society},
  series       = {Biochemical Society Transactions},
  title        = {Spare respiratory capacity, oxidative stress and excitotoxicity},
  url          = {http://dx.doi.org/10.1042/BST0371385},
  volume       = {37},
  year         = {2009},
}