Spare respiratory capacity, oxidative stress and excitotoxicity
(2009) In Biochemical Society Transactions 37. p.1385-1388- Abstract
- Chronic exposure to glutamate (glutamate excitotoxicity) exacerbates neuronal damage in the aftermath of stroke and is implicated in a variety of neurodegenerative disorders. mitochondria play a central role in the survival or death of the exposed neuron. calcium, oxidative stress and ATP insufficiency play closely interlocked roles that may be investigated with primary neuronal cultures.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1532915
- author
- Nicholls, David LU
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- oxidative, mitochondrion, ischaemia, glutamate, ATP, excitotoxicity, stress
- in
- Biochemical Society Transactions
- volume
- 37
- pages
- 1385 - 1388
- publisher
- Biochemical Society
- external identifiers
-
- wos:000272646000044
- scopus:70450207200
- ISSN
- 0300-5127
- DOI
- 10.1042/BST0371385
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Neuronal Survival (013212041)
- id
- 9dbe850f-174a-47d3-90ea-040568062a0a (old id 1532915)
- date added to LUP
- 2016-04-01 11:47:38
- date last changed
- 2022-03-28 03:10:02
@article{9dbe850f-174a-47d3-90ea-040568062a0a, abstract = {{Chronic exposure to glutamate (glutamate excitotoxicity) exacerbates neuronal damage in the aftermath of stroke and is implicated in a variety of neurodegenerative disorders. mitochondria play a central role in the survival or death of the exposed neuron. calcium, oxidative stress and ATP insufficiency play closely interlocked roles that may be investigated with primary neuronal cultures.}}, author = {{Nicholls, David}}, issn = {{0300-5127}}, keywords = {{oxidative; mitochondrion; ischaemia; glutamate; ATP; excitotoxicity; stress}}, language = {{eng}}, pages = {{1385--1388}}, publisher = {{Biochemical Society}}, series = {{Biochemical Society Transactions}}, title = {{Spare respiratory capacity, oxidative stress and excitotoxicity}}, url = {{http://dx.doi.org/10.1042/BST0371385}}, doi = {{10.1042/BST0371385}}, volume = {{37}}, year = {{2009}}, }