Release of model compounds from "plum-pudding"-type gels composed of microgel particles randomly dispersed in a gel matrix
(2004) In The Journal of Physical Chemistry Part B 108(30). p.10893-10898- Abstract
- A novel gel structure called the "plum-pudding" gel was described by us previously. I The gel was composed of randomly dispersed microgel particles ("plums") in a conventional hydrogel network. Depending on the preparation conditions, the microgels can be incorporated into the gel as expanded networks or dense collapsed globules. Where the microgel particles exist as collapsed globules, they have the potential to act as reservoirs for hydrophobic solutes, from which the solutes are released very slowly. The release of two model hydrophobic compounds (pyrene and BODIPY) from "plum-pudding" gels composed of 50:50 BAM:NIPAM microgels embedded in NIPA gel films was investigated. The release of pyrene was found to follow Fickian diffusion,... (More)
- A novel gel structure called the "plum-pudding" gel was described by us previously. I The gel was composed of randomly dispersed microgel particles ("plums") in a conventional hydrogel network. Depending on the preparation conditions, the microgels can be incorporated into the gel as expanded networks or dense collapsed globules. Where the microgel particles exist as collapsed globules, they have the potential to act as reservoirs for hydrophobic solutes, from which the solutes are released very slowly. The release of two model hydrophobic compounds (pyrene and BODIPY) from "plum-pudding" gels composed of 50:50 BAM:NIPAM microgels embedded in NIPA gel films was investigated. The release of pyrene was found to follow Fickian diffusion, while the release of BODIPY was found to be slightly non-Fickian. Thus, we propose that by controlling the attractiveness of the microgel particles to the solutes to be released, a range of release profiles can be obtained from pure-Fickian to almost any conceivable time scale. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/153939
- author
- Lynch, Iseult LU and Dawson, K A
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- in
- The Journal of Physical Chemistry Part B
- volume
- 108
- issue
- 30
- pages
- 10893 - 10898
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- wos:000222864200042
- scopus:4043170064
- ISSN
- 1520-5207
- DOI
- 10.1021/jp0487105
- language
- English
- LU publication?
- yes
- id
- eb6e72c2-c24a-4939-a6b6-6699047055eb (old id 153939)
- date added to LUP
- 2016-04-01 16:47:06
- date last changed
- 2022-03-22 21:08:32
@article{eb6e72c2-c24a-4939-a6b6-6699047055eb,
abstract = {{A novel gel structure called the "plum-pudding" gel was described by us previously. I The gel was composed of randomly dispersed microgel particles ("plums") in a conventional hydrogel network. Depending on the preparation conditions, the microgels can be incorporated into the gel as expanded networks or dense collapsed globules. Where the microgel particles exist as collapsed globules, they have the potential to act as reservoirs for hydrophobic solutes, from which the solutes are released very slowly. The release of two model hydrophobic compounds (pyrene and BODIPY) from "plum-pudding" gels composed of 50:50 BAM:NIPAM microgels embedded in NIPA gel films was investigated. The release of pyrene was found to follow Fickian diffusion, while the release of BODIPY was found to be slightly non-Fickian. Thus, we propose that by controlling the attractiveness of the microgel particles to the solutes to be released, a range of release profiles can be obtained from pure-Fickian to almost any conceivable time scale.}},
author = {{Lynch, Iseult and Dawson, K A}},
issn = {{1520-5207}},
language = {{eng}},
number = {{30}},
pages = {{10893--10898}},
publisher = {{The American Chemical Society (ACS)}},
series = {{The Journal of Physical Chemistry Part B}},
title = {{Release of model compounds from "plum-pudding"-type gels composed of microgel particles randomly dispersed in a gel matrix}},
url = {{http://dx.doi.org/10.1021/jp0487105}},
doi = {{10.1021/jp0487105}},
volume = {{108}},
year = {{2004}},
}