Breast tomosynthesis: Accuracy of tumor measurement compared with digital mammography and ultrasonography.
(2010) In Acta radiologica (Stockholm, Sweden : 1987) 51. p.240-247- Abstract
- Background: Mammographic tumor size measurement can be difficult because breast structures are superimposed onto a two-dimensional (2D) plane, potentially obscuring the tumor outline. Breast tomosynthesis (BT) is a 3D X-ray imaging technique in which low-dose images are acquired over a limited angular range at a total dose comparable to digital mammography (DM). These low-dose images are used to mathematically reconstruct a 3D image volume of the breast, thus reducing the problem of superimposed tissue. Purpose: To investigate whether breast cancer size can be more accurately assessed with breast tomosynthesis than with digital mammography and ultrasonography (US), by reducing the disturbance effect of the projected anatomy. Material and... (More)
- Background: Mammographic tumor size measurement can be difficult because breast structures are superimposed onto a two-dimensional (2D) plane, potentially obscuring the tumor outline. Breast tomosynthesis (BT) is a 3D X-ray imaging technique in which low-dose images are acquired over a limited angular range at a total dose comparable to digital mammography (DM). These low-dose images are used to mathematically reconstruct a 3D image volume of the breast, thus reducing the problem of superimposed tissue. Purpose: To investigate whether breast cancer size can be more accurately assessed with breast tomosynthesis than with digital mammography and ultrasonography (US), by reducing the disturbance effect of the projected anatomy. Material and Methods: A prototype BT system was used. The main inclusion criterion for BT examination was subtle but suspicious findings of breast cancer on 2D mammography. Sixty-two women with 73 breast cancers were included. BT, DM, and US sizes were measured independently by experienced radiologists without knowledge of the pathology results, which were used as reference. Results: The tumor outline could be determined in significantly more cases with BT (63) and US (60) than DM (49). BT and US size correlated well with pathology (R=0.86 and R=0.85, respectively), and significantly better than DM size (R=0.71). Accordingly, staging was significantly more accurate with BT than with DM. Conclusion: The study indicates that BT is superior to DM in the assessment of breast tumor size and stage. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1540543
- author
- Förnvik, Daniel LU ; Zackrisson, Sophia LU ; Ljungberg, Otto LU ; Svahn, Tony LU ; Timberg, Pontus LU ; Tingberg, Anders LU and Andersson, Ingvar LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta radiologica (Stockholm, Sweden : 1987)
- volume
- 51
- pages
- 240 - 247
- publisher
- SAGE Publications
- external identifiers
-
- wos:000275151700002
- pmid:20105090
- scopus:77749268123
- pmid:20105090
- ISSN
- 1600-0455
- DOI
- 10.3109/02841850903524447
- language
- English
- LU publication?
- yes
- id
- 7ee68173-b7f1-446d-9103-0a787a431360 (old id 1540543)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/20105090?dopt=Abstract
- date added to LUP
- 2016-04-04 09:07:58
- date last changed
- 2024-02-27 23:23:42
@article{7ee68173-b7f1-446d-9103-0a787a431360, abstract = {{Background: Mammographic tumor size measurement can be difficult because breast structures are superimposed onto a two-dimensional (2D) plane, potentially obscuring the tumor outline. Breast tomosynthesis (BT) is a 3D X-ray imaging technique in which low-dose images are acquired over a limited angular range at a total dose comparable to digital mammography (DM). These low-dose images are used to mathematically reconstruct a 3D image volume of the breast, thus reducing the problem of superimposed tissue. Purpose: To investigate whether breast cancer size can be more accurately assessed with breast tomosynthesis than with digital mammography and ultrasonography (US), by reducing the disturbance effect of the projected anatomy. Material and Methods: A prototype BT system was used. The main inclusion criterion for BT examination was subtle but suspicious findings of breast cancer on 2D mammography. Sixty-two women with 73 breast cancers were included. BT, DM, and US sizes were measured independently by experienced radiologists without knowledge of the pathology results, which were used as reference. Results: The tumor outline could be determined in significantly more cases with BT (63) and US (60) than DM (49). BT and US size correlated well with pathology (R=0.86 and R=0.85, respectively), and significantly better than DM size (R=0.71). Accordingly, staging was significantly more accurate with BT than with DM. Conclusion: The study indicates that BT is superior to DM in the assessment of breast tumor size and stage.}}, author = {{Förnvik, Daniel and Zackrisson, Sophia and Ljungberg, Otto and Svahn, Tony and Timberg, Pontus and Tingberg, Anders and Andersson, Ingvar}}, issn = {{1600-0455}}, language = {{eng}}, pages = {{240--247}}, publisher = {{SAGE Publications}}, series = {{Acta radiologica (Stockholm, Sweden : 1987)}}, title = {{Breast tomosynthesis: Accuracy of tumor measurement compared with digital mammography and ultrasonography.}}, url = {{http://dx.doi.org/10.3109/02841850903524447}}, doi = {{10.3109/02841850903524447}}, volume = {{51}}, year = {{2010}}, }