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Alcohol intoxication at 0.06 and 0.10% blood alcohol concentration changes segmental body movement coordination.

Patel, Mitesh LU ; Modig, Fredrik LU ; Magnusson, Måns LU and Fransson, Per-Anders LU (2010) In Experimental Brain Research 202. p.431-443
Abstract
Alcohol intoxication is the cause of many falls requiring emergency care. The control of upright standing balance is complex and comprises contributions from several partly independent mechanisms like coordination, feedback and feedforward control and adaptation. Analysis of the segmental body movement coordination offers one option to detect the severity of balance problems. The study aims were (1) to investigate whether alcohol intoxication at 0.06 and 0.10% blood alcohol concentration (BAC) affected the segmental movement pattern under unperturbed and perturbed standing; (2) whether alcohol affected the ability for movement pattern adaptation; (3) whether one's own subjective feeling of drunkenness correlated to the movement pattern... (More)
Alcohol intoxication is the cause of many falls requiring emergency care. The control of upright standing balance is complex and comprises contributions from several partly independent mechanisms like coordination, feedback and feedforward control and adaptation. Analysis of the segmental body movement coordination offers one option to detect the severity of balance problems. The study aims were (1) to investigate whether alcohol intoxication at 0.06 and 0.10% blood alcohol concentration (BAC) affected the segmental movement pattern under unperturbed and perturbed standing; (2) whether alcohol affected the ability for movement pattern adaptation; (3) whether one's own subjective feeling of drunkenness correlated to the movement pattern used. Twenty-five participants (13 women and 12 men, mean age 25.1 years) performed tests involving alcohol intoxication. Body movements were recorded at five locations (ankle, knee, hip, shoulder and head) during quiet standing and pseudorandom pulses of calf muscle vibration for 200 s with eyes closed or open. There was no significant effect of alcohol on the general movement pattern in unperturbed stance or on adaptation. However, when balance was repeatedly perturbed, knee movements became significantly less correlated to other body movements over time at 0.10% BAC and when visual information was unavailable, suggesting that the normal movement pattern could not be maintained for a longer period of time while under 0.10% BAC intoxication. Subjective feelings of drunkenness correlated often with a changed upper body movement pattern but less so with changed knee movements. Thus, an inability to relate drunkenness with changed knee movements may be a contributing factor to falls in addition to the direct effect of alcohol intoxication. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Experimental Brain Research
volume
202
pages
431 - 443
publisher
Springer
external identifiers
  • wos:000276220300015
  • pmid:20076951
  • scopus:77951094124
ISSN
0014-4819
DOI
10.1007/s00221-009-2150-5
language
English
LU publication?
yes
id
c2047c59-e6bb-4fbe-b2c6-6e96d915b873 (old id 1541037)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/20076951?dopt=Abstract
date added to LUP
2010-02-02 13:17:13
date last changed
2018-05-29 11:41:21
@article{c2047c59-e6bb-4fbe-b2c6-6e96d915b873,
  abstract     = {Alcohol intoxication is the cause of many falls requiring emergency care. The control of upright standing balance is complex and comprises contributions from several partly independent mechanisms like coordination, feedback and feedforward control and adaptation. Analysis of the segmental body movement coordination offers one option to detect the severity of balance problems. The study aims were (1) to investigate whether alcohol intoxication at 0.06 and 0.10% blood alcohol concentration (BAC) affected the segmental movement pattern under unperturbed and perturbed standing; (2) whether alcohol affected the ability for movement pattern adaptation; (3) whether one's own subjective feeling of drunkenness correlated to the movement pattern used. Twenty-five participants (13 women and 12 men, mean age 25.1 years) performed tests involving alcohol intoxication. Body movements were recorded at five locations (ankle, knee, hip, shoulder and head) during quiet standing and pseudorandom pulses of calf muscle vibration for 200 s with eyes closed or open. There was no significant effect of alcohol on the general movement pattern in unperturbed stance or on adaptation. However, when balance was repeatedly perturbed, knee movements became significantly less correlated to other body movements over time at 0.10% BAC and when visual information was unavailable, suggesting that the normal movement pattern could not be maintained for a longer period of time while under 0.10% BAC intoxication. Subjective feelings of drunkenness correlated often with a changed upper body movement pattern but less so with changed knee movements. Thus, an inability to relate drunkenness with changed knee movements may be a contributing factor to falls in addition to the direct effect of alcohol intoxication.},
  author       = {Patel, Mitesh and Modig, Fredrik and Magnusson, Måns and Fransson, Per-Anders},
  issn         = {0014-4819},
  language     = {eng},
  pages        = {431--443},
  publisher    = {Springer},
  series       = {Experimental Brain Research},
  title        = {Alcohol intoxication at 0.06 and 0.10% blood alcohol concentration changes segmental body movement coordination.},
  url          = {http://dx.doi.org/10.1007/s00221-009-2150-5},
  volume       = {202},
  year         = {2010},
}