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Solubilisation of model adjuvants by Pluronic block copolymers.

Sharp, Melissa LU ; Washington, Clive and Cosgrove, Terence (2010) In Journal of Colloid and Interface Science
Abstract
The effect of two model adjuvants (benzyl benzoate and benzyl alcohol) on the structure and dynamics of three Pluronic triblock copolymers (P85, P105 and F127) was studied using small-angle neutron scattering and pulsed-field gradient NMR. The two adjuvants studied have different aqueous solubilities. It was found that both adjuvants promoted the micellisation of the Pluronic block copolymers. In addition they lead to a swelling of the micelles, as shown by small-angle neutron scattering. From the pulsed-field gradient NMR results it was possible to determine the amount of adjuvant bound to the micelles.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Colloid and Interface Science
publisher
Elsevier
external identifiers
  • wos:000275799100029
  • pmid:20129623
  • scopus:77649235289
ISSN
1095-7103
DOI
10.1016/j.jcis.2010.01.005
language
English
LU publication?
yes
id
42227f13-f53c-443e-b616-dc0a1f0ee533 (old id 1552976)
date added to LUP
2010-03-08 13:23:02
date last changed
2018-05-29 11:58:01
@article{42227f13-f53c-443e-b616-dc0a1f0ee533,
  abstract     = {The effect of two model adjuvants (benzyl benzoate and benzyl alcohol) on the structure and dynamics of three Pluronic triblock copolymers (P85, P105 and F127) was studied using small-angle neutron scattering and pulsed-field gradient NMR. The two adjuvants studied have different aqueous solubilities. It was found that both adjuvants promoted the micellisation of the Pluronic block copolymers. In addition they lead to a swelling of the micelles, as shown by small-angle neutron scattering. From the pulsed-field gradient NMR results it was possible to determine the amount of adjuvant bound to the micelles.},
  author       = {Sharp, Melissa and Washington, Clive and Cosgrove, Terence},
  issn         = {1095-7103},
  language     = {eng},
  month        = {01},
  publisher    = {Elsevier},
  series       = {Journal of Colloid and Interface Science},
  title        = {Solubilisation of model adjuvants by Pluronic block copolymers.},
  url          = {http://dx.doi.org/10.1016/j.jcis.2010.01.005},
  year         = {2010},
}