Patient gender and radiopharmaceutical tracer is of minor importance for the interpretation of myocardial perfusion images using an artificial neural network.
Tägil, Kristina LU ; Underwood, S Richard ; Davies, Glyn ; Latus, Katherine A ; Ohlsson, Mattias LU
; Gotborg, Cecilia Wallin
and Edenbrandt, Lars
LU
(2006)
In Clinical Physiology and Functional Imaging
26(3).
p.146-150
- Abstract
- The purpose of this study was to assess the influence of patient gender and choice of perfusion tracer on computer-based interpretation of myocardial perfusion images. For the image interpretation, an automated method was used based on image processing and artificial neural network techniques. A total of 1000 patients were studied, all referred to the Royal Brompton Hospital in London for myocardial perfusion scintigraphy over a period of 1 year. The patients were randomized to receive either thallium or one of the two technetium tracers, methoxyisobutylisonitrile or tetrofosmin. Artificial neural networks were trained with either mixed gender or gender-specific and mixed tracer or tracer-specific training sets of different sizes. The... (More)
- The purpose of this study was to assess the influence of patient gender and choice of perfusion tracer on computer-based interpretation of myocardial perfusion images. For the image interpretation, an automated method was used based on image processing and artificial neural network techniques. A total of 1000 patients were studied, all referred to the Royal Brompton Hospital in London for myocardial perfusion scintigraphy over a period of 1 year. The patients were randomized to receive either thallium or one of the two technetium tracers, methoxyisobutylisonitrile or tetrofosmin. Artificial neural networks were trained with either mixed gender or gender-specific and mixed tracer or tracer-specific training sets of different sizes. The performance of the networks was assessed in separate test sets, with the interpretation of experienced physicians regarding the presence or absence of fixed or reversible defects in the images as the gold standard. The neural networks trained with large mixed gender training sets were as good as the networks trained with gender-specific data sets. In addition, the neural networks trained with large mixed tracer training sets were as good as or better than the networks trained with tracer-specific data sets. Our results indicate that the influence of patient gender and perfusion tracer are of minor importance for the computer-based interpretation of the myocardial perfusion images. The differences that occur can be compensated for by larger training sets. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/155716
- author
- Tägil, Kristina
LU
; Underwood, S Richard
; Davies, Glyn
; Latus, Katherine A
; Ohlsson, Mattias
LU
; Gotborg, Cecilia Wallin
and Edenbrandt, Lars
LU
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical Physiology and Functional Imaging
- volume
- 26
- issue
- 3
- pages
- 146 - 150
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000237093900002
- pmid:16640508
- scopus:33646045301
- pmid:16640508
- ISSN
- 1475-0961
- DOI
- 10.1111/j.1475-097X.2006.00668.x
- language
- English
- LU publication?
- yes
- id
- eeb7c22c-3106-49f0-b242-0ee83b3be371 (old id 155716)
- date added to LUP
- 2016-04-01 11:52:33
- date last changed
- 2024-01-07 23:51:14
@article{eeb7c22c-3106-49f0-b242-0ee83b3be371,
abstract = {{The purpose of this study was to assess the influence of patient gender and choice of perfusion tracer on computer-based interpretation of myocardial perfusion images. For the image interpretation, an automated method was used based on image processing and artificial neural network techniques. A total of 1000 patients were studied, all referred to the Royal Brompton Hospital in London for myocardial perfusion scintigraphy over a period of 1 year. The patients were randomized to receive either thallium or one of the two technetium tracers, methoxyisobutylisonitrile or tetrofosmin. Artificial neural networks were trained with either mixed gender or gender-specific and mixed tracer or tracer-specific training sets of different sizes. The performance of the networks was assessed in separate test sets, with the interpretation of experienced physicians regarding the presence or absence of fixed or reversible defects in the images as the gold standard. The neural networks trained with large mixed gender training sets were as good as the networks trained with gender-specific data sets. In addition, the neural networks trained with large mixed tracer training sets were as good as or better than the networks trained with tracer-specific data sets. Our results indicate that the influence of patient gender and perfusion tracer are of minor importance for the computer-based interpretation of the myocardial perfusion images. The differences that occur can be compensated for by larger training sets.}},
author = {{Tägil, Kristina and Underwood, S Richard and Davies, Glyn and Latus, Katherine A and Ohlsson, Mattias and Gotborg, Cecilia Wallin and Edenbrandt, Lars}},
issn = {{1475-0961}},
language = {{eng}},
number = {{3}},
pages = {{146--150}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Clinical Physiology and Functional Imaging}},
title = {{Patient gender and radiopharmaceutical tracer is of minor importance for the interpretation of myocardial perfusion images using an artificial neural network.}},
url = {{http://dx.doi.org/10.1111/j.1475-097X.2006.00668.x}},
doi = {{10.1111/j.1475-097X.2006.00668.x}},
volume = {{26}},
year = {{2006}},
}