How often is a low 5-min Apgar score in term newborns due to asphyxia?
(2007) In European Journal of Obstetrics, Gynecology, and Reproductive Biology 130(2). p.169-175- Abstract
- Objective: To evaluate how often low 5-min Apgar scores (AS(5-min)) at term are associated with asphyxia. Study design: A cohort- and case-control study, including all 183 term infants with AS(5-min) below 7 born at Lund University Hospital during 1993-2002, antepartum deaths excluded. The control group included 183 randomly selected term newborns with AS(5-min) 9-10. Cardiotocography (CTG) traces were assessed blinded to group and outcome. Obstetric and pediatric files were reviewed. Results: After excluding infants with severe malformations, indications of hypoxia were found at the following rates in cases with AS(5-min) below 4 (N = 30), scores 4-6 (N = 143), and controls (N = 182)-abnormal admission CTG: 38%, 8% and 0.6%; abnormal CTG... (More)
- Objective: To evaluate how often low 5-min Apgar scores (AS(5-min)) at term are associated with asphyxia. Study design: A cohort- and case-control study, including all 183 term infants with AS(5-min) below 7 born at Lund University Hospital during 1993-2002, antepartum deaths excluded. The control group included 183 randomly selected term newborns with AS(5-min) 9-10. Cardiotocography (CTG) traces were assessed blinded to group and outcome. Obstetric and pediatric files were reviewed. Results: After excluding infants with severe malformations, indications of hypoxia were found at the following rates in cases with AS(5-min) below 4 (N = 30), scores 4-6 (N = 143), and controls (N = 182)-abnormal admission CTG: 38%, 8% and 0.6%; abnormal CTG before birth: 88%, 69% and 18%; obstetrical catastrophe: 28%, 6% and 0.6%; interventions for fetal distress: 83%, 48% and 9%; cord artery pH below 7.15: 69%, 54% and 7%; hypoxic ischemic encephalopathy or hypoxic death: 70%, 14% and none. All differences between each case group and controls were statistically significant (p < 0.0001). Conclusions: In the absence of severe malformations, the vast majority of AS(5-min) below 4, and at least half of scores 4-6 could be attributed to birth asphyxia. Signs of hypoxia usually appeared during labor, but were present at admission in 38% of cases with AS(5-min) below 4. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/155859
- author
- Hogan, Linda ; Ingemarsson, Ingemar LU ; Thorngren-Jerneck, Kristina LU and Herbst, Andreas LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- perinatal, neonatal, HIE, acidosis, admission test, cardiotocography, asphyxia, Apgar score, term
- in
- European Journal of Obstetrics, Gynecology, and Reproductive Biology
- volume
- 130
- issue
- 2
- pages
- 169 - 175
- publisher
- Elsevier
- external identifiers
-
- wos:000244283600005
- scopus:33846254634
- ISSN
- 0301-2115
- DOI
- 10.1016/j.ejogrb.2006.03.002
- language
- English
- LU publication?
- yes
- id
- d1c3f11d-83e2-4560-a7b2-68a22c382e1d (old id 155859)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16621222&dopt=Abstract
- date added to LUP
- 2016-04-01 11:45:40
- date last changed
- 2022-03-13 00:17:45
@article{d1c3f11d-83e2-4560-a7b2-68a22c382e1d, abstract = {{Objective: To evaluate how often low 5-min Apgar scores (AS(5-min)) at term are associated with asphyxia. Study design: A cohort- and case-control study, including all 183 term infants with AS(5-min) below 7 born at Lund University Hospital during 1993-2002, antepartum deaths excluded. The control group included 183 randomly selected term newborns with AS(5-min) 9-10. Cardiotocography (CTG) traces were assessed blinded to group and outcome. Obstetric and pediatric files were reviewed. Results: After excluding infants with severe malformations, indications of hypoxia were found at the following rates in cases with AS(5-min) below 4 (N = 30), scores 4-6 (N = 143), and controls (N = 182)-abnormal admission CTG: 38%, 8% and 0.6%; abnormal CTG before birth: 88%, 69% and 18%; obstetrical catastrophe: 28%, 6% and 0.6%; interventions for fetal distress: 83%, 48% and 9%; cord artery pH below 7.15: 69%, 54% and 7%; hypoxic ischemic encephalopathy or hypoxic death: 70%, 14% and none. All differences between each case group and controls were statistically significant (p < 0.0001). Conclusions: In the absence of severe malformations, the vast majority of AS(5-min) below 4, and at least half of scores 4-6 could be attributed to birth asphyxia. Signs of hypoxia usually appeared during labor, but were present at admission in 38% of cases with AS(5-min) below 4.}}, author = {{Hogan, Linda and Ingemarsson, Ingemar and Thorngren-Jerneck, Kristina and Herbst, Andreas}}, issn = {{0301-2115}}, keywords = {{perinatal; neonatal; HIE; acidosis; admission test; cardiotocography; asphyxia; Apgar score; term}}, language = {{eng}}, number = {{2}}, pages = {{169--175}}, publisher = {{Elsevier}}, series = {{European Journal of Obstetrics, Gynecology, and Reproductive Biology}}, title = {{How often is a low 5-min Apgar score in term newborns due to asphyxia?}}, url = {{http://dx.doi.org/10.1016/j.ejogrb.2006.03.002}}, doi = {{10.1016/j.ejogrb.2006.03.002}}, volume = {{130}}, year = {{2007}}, }