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The Cardiac State Diagram As A Novel Approach For The Evaluation Of Pre- And Post-Ejection Phases Of The Cardiac Cycle In Asphyxiated Fetal Lambs

Wagstrom, Elle; Johnson, Jonas; Ferm-Widlund, Kjerstin; Elmstedt, Nina; Liuba, Karina LU ; Lind, Britta; Brodin, Lars-Ake; Lundback, Stig and Westgren, Magnus (2013) In Ultrasound in Medicine and Biology 39(9). p.1682-1687
Abstract
The aim of this study was to investigate myocardial wall motion using echocardiography and color-coded tissue velocity imaging and to generate a cardiac state diagram for evaluation of the duration of the pre- and post-ejection phases in asphyxiated fetal lambs. Six near-term lambs were partly exteriorized and brought to cardiac arrest through asphyxia. Echocardiography measurements were recorded simultaneously with arterial blood sampling for lactate and blood gases. All fetal lambs exhibited prolongation of the pre- and post-ejection phases at the time when the most pronounced changes in lactate concentration and pH occurred. The mean change in duration of the pre- and post-ejection phases for all fetal lambs was 36 +/- 7 ms (p <... (More)
The aim of this study was to investigate myocardial wall motion using echocardiography and color-coded tissue velocity imaging and to generate a cardiac state diagram for evaluation of the duration of the pre- and post-ejection phases in asphyxiated fetal lambs. Six near-term lambs were partly exteriorized and brought to cardiac arrest through asphyxia. Echocardiography measurements were recorded simultaneously with arterial blood sampling for lactate and blood gases. All fetal lambs exhibited prolongation of the pre- and post-ejection phases at the time when the most pronounced changes in lactate concentration and pH occurred. The mean change in duration of the pre- and post-ejection phases for all fetal lambs was 36 +/- 7 ms (p < 0.002) and 77 +/- 17 ms (p < 0.019), respectively, and the percentage change was 50% (p < 0.001) and 38% (p < 0.049), respectively. As asphyxia progressed in fetal lambs, the duration of the pre- and post-ejection phases increased. The cardiac state diagram has the potential to be a comprehensible tool for detecting fetal asphyxia. (E-mail: elle.wagstrom@karolinska.se) (C) 2013 World Federation for Ultrasound in Medicine & Biology. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cardiac state diagram, Cardiac time intervals, Doppler, Fetal, physiology, Myocardial motion, Asphyxia, Tissue velocity imaging, Echocardiography
in
Ultrasound in Medicine and Biology
volume
39
issue
9
pages
1682 - 1687
publisher
Elsevier
external identifiers
  • wos:000324052300017
  • scopus:84881667580
ISSN
0301-5629
DOI
10.1016/j.ultrasmedbio.2013.04.012
language
English
LU publication?
yes
id
15603569-71e3-403f-a553-762e2b53a45b (old id 4106666)
date added to LUP
2013-11-07 14:28:33
date last changed
2019-07-09 01:23:48
@article{15603569-71e3-403f-a553-762e2b53a45b,
  abstract     = {The aim of this study was to investigate myocardial wall motion using echocardiography and color-coded tissue velocity imaging and to generate a cardiac state diagram for evaluation of the duration of the pre- and post-ejection phases in asphyxiated fetal lambs. Six near-term lambs were partly exteriorized and brought to cardiac arrest through asphyxia. Echocardiography measurements were recorded simultaneously with arterial blood sampling for lactate and blood gases. All fetal lambs exhibited prolongation of the pre- and post-ejection phases at the time when the most pronounced changes in lactate concentration and pH occurred. The mean change in duration of the pre- and post-ejection phases for all fetal lambs was 36 +/- 7 ms (p &lt; 0.002) and 77 +/- 17 ms (p &lt; 0.019), respectively, and the percentage change was 50% (p &lt; 0.001) and 38% (p &lt; 0.049), respectively. As asphyxia progressed in fetal lambs, the duration of the pre- and post-ejection phases increased. The cardiac state diagram has the potential to be a comprehensible tool for detecting fetal asphyxia. (E-mail: elle.wagstrom@karolinska.se) (C) 2013 World Federation for Ultrasound in Medicine &amp; Biology.},
  author       = {Wagstrom, Elle and Johnson, Jonas and Ferm-Widlund, Kjerstin and Elmstedt, Nina and Liuba, Karina and Lind, Britta and Brodin, Lars-Ake and Lundback, Stig and Westgren, Magnus},
  issn         = {0301-5629},
  keyword      = {Cardiac state diagram,Cardiac time intervals,Doppler,Fetal,physiology,Myocardial motion,Asphyxia,Tissue velocity imaging,Echocardiography},
  language     = {eng},
  number       = {9},
  pages        = {1682--1687},
  publisher    = {Elsevier},
  series       = {Ultrasound in Medicine and Biology},
  title        = {The Cardiac State Diagram As A Novel Approach For The Evaluation Of Pre- And Post-Ejection Phases Of The Cardiac Cycle In Asphyxiated Fetal Lambs},
  url          = {http://dx.doi.org/10.1016/j.ultrasmedbio.2013.04.012},
  volume       = {39},
  year         = {2013},
}