The Cardiac State Diagram As A Novel Approach For The Evaluation Of Pre- And Post-Ejection Phases Of The Cardiac Cycle In Asphyxiated Fetal Lambs
(2013) In Ultrasound in Medicine and Biology 39(9). p.1682-1687- Abstract
- The aim of this study was to investigate myocardial wall motion using echocardiography and color-coded tissue velocity imaging and to generate a cardiac state diagram for evaluation of the duration of the pre- and post-ejection phases in asphyxiated fetal lambs. Six near-term lambs were partly exteriorized and brought to cardiac arrest through asphyxia. Echocardiography measurements were recorded simultaneously with arterial blood sampling for lactate and blood gases. All fetal lambs exhibited prolongation of the pre- and post-ejection phases at the time when the most pronounced changes in lactate concentration and pH occurred. The mean change in duration of the pre- and post-ejection phases for all fetal lambs was 36 +/- 7 ms (p <... (More)
- The aim of this study was to investigate myocardial wall motion using echocardiography and color-coded tissue velocity imaging and to generate a cardiac state diagram for evaluation of the duration of the pre- and post-ejection phases in asphyxiated fetal lambs. Six near-term lambs were partly exteriorized and brought to cardiac arrest through asphyxia. Echocardiography measurements were recorded simultaneously with arterial blood sampling for lactate and blood gases. All fetal lambs exhibited prolongation of the pre- and post-ejection phases at the time when the most pronounced changes in lactate concentration and pH occurred. The mean change in duration of the pre- and post-ejection phases for all fetal lambs was 36 +/- 7 ms (p < 0.002) and 77 +/- 17 ms (p < 0.019), respectively, and the percentage change was 50% (p < 0.001) and 38% (p < 0.049), respectively. As asphyxia progressed in fetal lambs, the duration of the pre- and post-ejection phases increased. The cardiac state diagram has the potential to be a comprehensible tool for detecting fetal asphyxia. (E-mail: elle.wagstrom@karolinska.se) (C) 2013 World Federation for Ultrasound in Medicine & Biology. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4106666
- author
- Wagstrom, Elle ; Johnson, Jonas ; Ferm-Widlund, Kjerstin ; Elmstedt, Nina ; Liuba, Karina LU ; Lind, Britta ; Brodin, Lars-Ake ; Lundback, Stig and Westgren, Magnus
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Cardiac state diagram, Cardiac time intervals, Doppler, Fetal, physiology, Myocardial motion, Asphyxia, Tissue velocity imaging, Echocardiography
- in
- Ultrasound in Medicine and Biology
- volume
- 39
- issue
- 9
- pages
- 1682 - 1687
- publisher
- Elsevier
- external identifiers
-
- wos:000324052300017
- scopus:84881667580
- pmid:23849391
- ISSN
- 0301-5629
- DOI
- 10.1016/j.ultrasmedbio.2013.04.012
- language
- English
- LU publication?
- yes
- id
- 15603569-71e3-403f-a553-762e2b53a45b (old id 4106666)
- date added to LUP
- 2016-04-01 10:40:35
- date last changed
- 2022-02-17 20:16:14
@article{15603569-71e3-403f-a553-762e2b53a45b, abstract = {{The aim of this study was to investigate myocardial wall motion using echocardiography and color-coded tissue velocity imaging and to generate a cardiac state diagram for evaluation of the duration of the pre- and post-ejection phases in asphyxiated fetal lambs. Six near-term lambs were partly exteriorized and brought to cardiac arrest through asphyxia. Echocardiography measurements were recorded simultaneously with arterial blood sampling for lactate and blood gases. All fetal lambs exhibited prolongation of the pre- and post-ejection phases at the time when the most pronounced changes in lactate concentration and pH occurred. The mean change in duration of the pre- and post-ejection phases for all fetal lambs was 36 +/- 7 ms (p < 0.002) and 77 +/- 17 ms (p < 0.019), respectively, and the percentage change was 50% (p < 0.001) and 38% (p < 0.049), respectively. As asphyxia progressed in fetal lambs, the duration of the pre- and post-ejection phases increased. The cardiac state diagram has the potential to be a comprehensible tool for detecting fetal asphyxia. (E-mail: elle.wagstrom@karolinska.se) (C) 2013 World Federation for Ultrasound in Medicine & Biology.}}, author = {{Wagstrom, Elle and Johnson, Jonas and Ferm-Widlund, Kjerstin and Elmstedt, Nina and Liuba, Karina and Lind, Britta and Brodin, Lars-Ake and Lundback, Stig and Westgren, Magnus}}, issn = {{0301-5629}}, keywords = {{Cardiac state diagram; Cardiac time intervals; Doppler; Fetal; physiology; Myocardial motion; Asphyxia; Tissue velocity imaging; Echocardiography}}, language = {{eng}}, number = {{9}}, pages = {{1682--1687}}, publisher = {{Elsevier}}, series = {{Ultrasound in Medicine and Biology}}, title = {{The Cardiac State Diagram As A Novel Approach For The Evaluation Of Pre- And Post-Ejection Phases Of The Cardiac Cycle In Asphyxiated Fetal Lambs}}, url = {{http://dx.doi.org/10.1016/j.ultrasmedbio.2013.04.012}}, doi = {{10.1016/j.ultrasmedbio.2013.04.012}}, volume = {{39}}, year = {{2013}}, }