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Cubic phase nanoparticles (Cubosome): Principles for controlling size, structure, and stability

Barauskas, Justas LU ; Johnsson, Markus LU ; Joabsson, F and Tiberg, Fredrik LU (2005) In Langmuir 21(6). p.2569-2577
Abstract
Methods and compositions for producing lipid-based cubic phase nanoparticles were first discovered in the 1990s. Since then a number of studies have been presented, but little is known about how to control key properties such as particle size, morphology, and stability of cubic phase dispersions. In the present work we give examples of how these properties can be tuned by composition and processing conditions. Importantly we show that stable particle dispersions with consistent size and structure can be produced by a simple processing scheme comprising a homogenization and heat treatment step.
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Langmuir
volume
21
issue
6
pages
2569 - 2577
publisher
The American Chemical Society (ACS)
external identifiers
  • pmid:15752054
  • wos:000227578700064
  • scopus:15844373752
ISSN
0743-7463
DOI
10.1021/la047590p
language
English
LU publication?
yes
id
8befc071-a3fa-4b74-95cc-7724256024fa (old id 157181)
date added to LUP
2016-04-01 12:03:09
date last changed
2022-04-28 23:45:11
@article{8befc071-a3fa-4b74-95cc-7724256024fa,
  abstract     = {{Methods and compositions for producing lipid-based cubic phase nanoparticles were first discovered in the 1990s. Since then a number of studies have been presented, but little is known about how to control key properties such as particle size, morphology, and stability of cubic phase dispersions. In the present work we give examples of how these properties can be tuned by composition and processing conditions. Importantly we show that stable particle dispersions with consistent size and structure can be produced by a simple processing scheme comprising a homogenization and heat treatment step.}},
  author       = {{Barauskas, Justas and Johnsson, Markus and Joabsson, F and Tiberg, Fredrik}},
  issn         = {{0743-7463}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{2569--2577}},
  publisher    = {{The American Chemical Society (ACS)}},
  series       = {{Langmuir}},
  title        = {{Cubic phase nanoparticles (Cubosome): Principles for controlling size, structure, and stability}},
  url          = {{http://dx.doi.org/10.1021/la047590p}},
  doi          = {{10.1021/la047590p}},
  volume       = {{21}},
  year         = {{2005}},
}