Assessment of changes in volume and vascularity of the ovaries during the normal menstrual cycle using three-dimensional power Doppler ultrasound.
Jokubkiene, Ligita LU ; Sladkevicius, Povilas LU
; Rovas, Linas
LU
and Valentin, Lil
LU
(2006)
In Human Reproduction
21(Jun 28).
p.2661-2668
- Abstract
- BACKGROUND: Our aim was to describe changes in the volume and vascularization of both ovaries, the dominant follicle and the corpus luteum during the normal menstrual cycle using three-dimensional (3D) power Doppler ultrasound. METHODS: Fourteen healthy volunteers underwent serial transvaginal 3D ultrasound examinations of both ovaries on cycle day 2, 3 or 4, then daily from cycle day 9 until follicular rupture and 1, 2, 5, 7 and 12 days after follicular rupture. The volume and vascular indices of the ovaries, the dominant follicle and the corpus luteum were calculated off-line using virtual organ computer-aided analysis (VOCAL(TM)) software. RESULTS: The volume of the dominant ovary increased during the follicular phase, decreased after... (More)
- BACKGROUND: Our aim was to describe changes in the volume and vascularization of both ovaries, the dominant follicle and the corpus luteum during the normal menstrual cycle using three-dimensional (3D) power Doppler ultrasound. METHODS: Fourteen healthy volunteers underwent serial transvaginal 3D ultrasound examinations of both ovaries on cycle day 2, 3 or 4, then daily from cycle day 9 until follicular rupture and 1, 2, 5, 7 and 12 days after follicular rupture. The volume and vascular indices of the ovaries, the dominant follicle and the corpus luteum were calculated off-line using virtual organ computer-aided analysis (VOCAL(TM)) software. RESULTS: The volume of the dominant ovary increased during the follicular phase, decreased after follicular rupture and then increased again during the luteal phase. Vascular indices in the dominant ovary and the dominant follicle/corpus luteum increased during the follicular phase, the vascular flow index (VFI) in the dominant follicle being on average (median) 1.7 times higher on the day before ovulation than 4 days before ovulation (P = 0.003). The vascular indices continued to rise after follicular rupture so that VFI in the corpus luteum was on average (median) 3.1 times higher 7 days after ovulation than in the follicle on the day before ovulation (P = 0.0002). The volume and vascular indices in the non-dominant ovary manifested no unequivocal changes during the menstrual cycle. CONCLUSIONS: Substantial changes occur in volume and vascularization of the dominant ovary during the normal menstrual cycle. 3D power Doppler ultrasound may become a useful tool for assessing pathological changes in the ovaries, for example, in subfertile patients. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/158315
- author
- Jokubkiene, Ligita
LU
; Sladkevicius, Povilas
LU
; Rovas, Linas
LU
and Valentin, Lil
LU
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- ovary, corpus luteum, menstrual cycle, three-dimensional imaging, ovarian follicle
- in
- Human Reproduction
- volume
- 21
- issue
- Jun 28
- pages
- 2661 - 2668
- publisher
- Oxford University Press
- external identifiers
-
- pmid:16775158
- wos:000240928600032
- scopus:33749595640
- ISSN
- 0268-1161
- DOI
- 10.1093/humrep/del211
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Obstetric, Gynaecological and Prenatal Ultrasound Research Unit (013242720), Pediatrics/Urology/Gynecology/Endocrinology (013240400)
- id
- 6c531559-021a-4ec6-b9d1-574553a5cb19 (old id 158315)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16775158&dopt=Abstract
- date added to LUP
- 2016-04-01 12:10:26
- date last changed
- 2022-05-19 02:04:48
@article{6c531559-021a-4ec6-b9d1-574553a5cb19,
abstract = {{BACKGROUND: Our aim was to describe changes in the volume and vascularization of both ovaries, the dominant follicle and the corpus luteum during the normal menstrual cycle using three-dimensional (3D) power Doppler ultrasound. METHODS: Fourteen healthy volunteers underwent serial transvaginal 3D ultrasound examinations of both ovaries on cycle day 2, 3 or 4, then daily from cycle day 9 until follicular rupture and 1, 2, 5, 7 and 12 days after follicular rupture. The volume and vascular indices of the ovaries, the dominant follicle and the corpus luteum were calculated off-line using virtual organ computer-aided analysis (VOCAL(TM)) software. RESULTS: The volume of the dominant ovary increased during the follicular phase, decreased after follicular rupture and then increased again during the luteal phase. Vascular indices in the dominant ovary and the dominant follicle/corpus luteum increased during the follicular phase, the vascular flow index (VFI) in the dominant follicle being on average (median) 1.7 times higher on the day before ovulation than 4 days before ovulation (P = 0.003). The vascular indices continued to rise after follicular rupture so that VFI in the corpus luteum was on average (median) 3.1 times higher 7 days after ovulation than in the follicle on the day before ovulation (P = 0.0002). The volume and vascular indices in the non-dominant ovary manifested no unequivocal changes during the menstrual cycle. CONCLUSIONS: Substantial changes occur in volume and vascularization of the dominant ovary during the normal menstrual cycle. 3D power Doppler ultrasound may become a useful tool for assessing pathological changes in the ovaries, for example, in subfertile patients.}},
author = {{Jokubkiene, Ligita and Sladkevicius, Povilas and Rovas, Linas and Valentin, Lil}},
issn = {{0268-1161}},
keywords = {{ovary; corpus luteum; menstrual cycle; three-dimensional imaging; ovarian follicle}},
language = {{eng}},
number = {{Jun 28}},
pages = {{2661--2668}},
publisher = {{Oxford University Press}},
series = {{Human Reproduction}},
title = {{Assessment of changes in volume and vascularity of the ovaries during the normal menstrual cycle using three-dimensional power Doppler ultrasound.}},
url = {{http://dx.doi.org/10.1093/humrep/del211}},
doi = {{10.1093/humrep/del211}},
volume = {{21}},
year = {{2006}},
}