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Contact allergy to gold as a model for clinical-experimental research

Möller, Halvor LU (2010) In Contact Dermatitis 62(4). p.193-200
Abstract
The high frequency of contact allergy to gold in patients with dermatitis was established after exhaustive skin testing, determining the right test agent, the best concentration, and repeated test readings. Metallic gold in contact with skin is slowly ionized, permitting absorption and haptenisation. Contact allergy to gold is statistically correlated to the presence of dental gold. But in many case reports it has also been attributed to wearing gold jewellery, albeit not statistically demonstrated. Epicutaneous testing with gold salts increases the blood gold level, and by intramuscular injection systemic contact dermatitis is provoked in an allergic individual. In coronary heart disease, gold-coated intravascular stents have been shown... (More)
The high frequency of contact allergy to gold in patients with dermatitis was established after exhaustive skin testing, determining the right test agent, the best concentration, and repeated test readings. Metallic gold in contact with skin is slowly ionized, permitting absorption and haptenisation. Contact allergy to gold is statistically correlated to the presence of dental gold. But in many case reports it has also been attributed to wearing gold jewellery, albeit not statistically demonstrated. Epicutaneous testing with gold salts increases the blood gold level, and by intramuscular injection systemic contact dermatitis is provoked in an allergic individual. In coronary heart disease, gold-coated intravascular stents have been shown to be correlated to contact allergy and even to an increased risk of restenosis. Gold is far from inert. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
metallic gold, jewellery, ionization, sodium thiosulfate, gold, gold allergy, dental gold, blood concentration, coronary stent, systemic contact dermatitis, patch test
in
Contact Dermatitis
volume
62
issue
4
pages
193 - 200
publisher
Federation of European Neuroscience Societies and Blackwell Publishing Ltd
external identifiers
  • wos:000276167600001
  • pmid:20433442
  • scopus:77950476214
ISSN
0105-1873
DOI
10.1111/j.1600-0536.2010.01671.x
language
English
LU publication?
yes
id
226a8424-e926-4a74-8483-04efaf8ddf46 (old id 1587129)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/20433442?dopt=Abstract
date added to LUP
2010-04-27 09:44:10
date last changed
2018-06-17 03:22:42
@article{226a8424-e926-4a74-8483-04efaf8ddf46,
  abstract     = {The high frequency of contact allergy to gold in patients with dermatitis was established after exhaustive skin testing, determining the right test agent, the best concentration, and repeated test readings. Metallic gold in contact with skin is slowly ionized, permitting absorption and haptenisation. Contact allergy to gold is statistically correlated to the presence of dental gold. But in many case reports it has also been attributed to wearing gold jewellery, albeit not statistically demonstrated. Epicutaneous testing with gold salts increases the blood gold level, and by intramuscular injection systemic contact dermatitis is provoked in an allergic individual. In coronary heart disease, gold-coated intravascular stents have been shown to be correlated to contact allergy and even to an increased risk of restenosis. Gold is far from inert.},
  author       = {Möller, Halvor},
  issn         = {0105-1873},
  keyword      = {metallic gold,jewellery,ionization,sodium thiosulfate,gold,gold allergy,dental gold,blood concentration,coronary stent,systemic contact dermatitis,patch test},
  language     = {eng},
  number       = {4},
  pages        = {193--200},
  publisher    = {Federation of European Neuroscience Societies and Blackwell Publishing Ltd},
  series       = {Contact Dermatitis},
  title        = {Contact allergy to gold as a model for clinical-experimental research},
  url          = {http://dx.doi.org/10.1111/j.1600-0536.2010.01671.x},
  volume       = {62},
  year         = {2010},
}