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Intra-observer variability of longitudinal displacement and intramural shear strain measurements of the arterial wall using ultrasound noninvasively in vivo.

Cinthio, Magnus and Rydén Ahlgren, Åsa LU (2010) In Ultrasound in Medicine and Biology 36(5). p.697-704
Abstract
Using a recently developed high-resolution noninvasive ultrasonic method, we recently demonstrated that the intima-media complex of the common carotid artery show a bidirectional multiphasic longitudinal displacement of the same magnitude as the diameter change during the cardiac cycle. The longitudinal movement of the adventitial region was smaller, thus, we identified shear strain and, thus, shear stress, within the arterial wall. The aim of this study was to evaluate the intra-observer variability of measurement of the longitudinal displacement of the intima-media complex and the intramural shear strain of the common carotid artery in vivo using the new ultrasonic method. The evaluation was carried out by comparing two consecutive... (More)
Using a recently developed high-resolution noninvasive ultrasonic method, we recently demonstrated that the intima-media complex of the common carotid artery show a bidirectional multiphasic longitudinal displacement of the same magnitude as the diameter change during the cardiac cycle. The longitudinal movement of the adventitial region was smaller, thus, we identified shear strain and, thus, shear stress, within the arterial wall. The aim of this study was to evaluate the intra-observer variability of measurement of the longitudinal displacement of the intima-media complex and the intramural shear strain of the common carotid artery in vivo using the new ultrasonic method. The evaluation was carried out by comparing two consecutive measurements on the common carotid artery of 20 healthy human subjects. According to the method of Bland Altman, we show that the systematic and random differences for the different phases of movement are acceptable in comparison to the measured displacement and no significant differences between the two measurements could be detected (p > 0.05 for all measured parameters). The coefficient of variation (CV) for measurement of the different phases of movement was <or=16%, including short-term physiologic variations. The higher variability in the measurement of the intramural shear strain (CV = 24%) has several explanations, which are discussed. In conclusion, this study shows that the present first ultrasonic method for high-resolution measurement of the longitudinal movement of the arterial wall is reliable and satisfactory for the further research of the longitudinal movement of the arterial wall in vivo. Further studies on the longitudinal movement of the arterial wall are important for developing an improved understanding of the physiology and the pathophysiology of the cardiovascular system. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Ultrasound in Medicine and Biology
volume
36
issue
5
pages
697 - 704
publisher
Elsevier
external identifiers
  • wos:000278012600002
  • pmid:20420967
  • scopus:77952307567
ISSN
0301-5629
DOI
10.1016/j.ultrasmedbio.2010.02.016
language
English
LU publication?
yes
id
c7fdde30-b2b4-4457-8dd6-5e3d6dd6f736 (old id 1594813)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/20420967?dopt=Abstract
date added to LUP
2010-05-04 23:00:12
date last changed
2018-06-10 04:50:54
@article{c7fdde30-b2b4-4457-8dd6-5e3d6dd6f736,
  abstract     = {Using a recently developed high-resolution noninvasive ultrasonic method, we recently demonstrated that the intima-media complex of the common carotid artery show a bidirectional multiphasic longitudinal displacement of the same magnitude as the diameter change during the cardiac cycle. The longitudinal movement of the adventitial region was smaller, thus, we identified shear strain and, thus, shear stress, within the arterial wall. The aim of this study was to evaluate the intra-observer variability of measurement of the longitudinal displacement of the intima-media complex and the intramural shear strain of the common carotid artery in vivo using the new ultrasonic method. The evaluation was carried out by comparing two consecutive measurements on the common carotid artery of 20 healthy human subjects. According to the method of Bland Altman, we show that the systematic and random differences for the different phases of movement are acceptable in comparison to the measured displacement and no significant differences between the two measurements could be detected (p &gt; 0.05 for all measured parameters). The coefficient of variation (CV) for measurement of the different phases of movement was &lt;or=16%, including short-term physiologic variations. The higher variability in the measurement of the intramural shear strain (CV = 24%) has several explanations, which are discussed. In conclusion, this study shows that the present first ultrasonic method for high-resolution measurement of the longitudinal movement of the arterial wall is reliable and satisfactory for the further research of the longitudinal movement of the arterial wall in vivo. Further studies on the longitudinal movement of the arterial wall are important for developing an improved understanding of the physiology and the pathophysiology of the cardiovascular system.},
  author       = {Cinthio, Magnus and Rydén Ahlgren, Åsa},
  issn         = {0301-5629},
  language     = {eng},
  number       = {5},
  pages        = {697--704},
  publisher    = {Elsevier},
  series       = {Ultrasound in Medicine and Biology},
  title        = {Intra-observer variability of longitudinal displacement and intramural shear strain measurements of the arterial wall using ultrasound noninvasively in vivo.},
  url          = {http://dx.doi.org/10.1016/j.ultrasmedbio.2010.02.016},
  volume       = {36},
  year         = {2010},
}