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Hemodynamic Responses to Speech and Music in Newborn Infants

Kotilahti, Kalle; Nissila, Ilkka; Nasi, Tiina; Lipiainen, Lauri; Noponen, Tommi; Merilainen, Pekka; Huotilainen, Minna and Fellman, Vineta LU (2010) In Human Brain Mapping 31(4). p.595-603
Abstract
We used near-infrared spectroscopy (NIRS) to study responses to speech and music on the auditory cortices of 13 healthy full-term newborn infants during natural sleep. The purpose of the study was to investigate the lateralization of speech and music responses at this stage of development. NIRS data was recorded from eight positions on both hemispheres simultaneously with electroencephalography, electrooculography, electrocardiography, pulse oximetry, and inclinometry. In 11 subjects, statistically significant (P < 0.02) oxygenated (HbO(2)) and total hemoglobin (HbT) responses were recorded. Both stimulus types elicited significant HbO(2) and HUT responses on both hemispheres in five subjects. Six of the 11 subjects had positive HbO(2)... (More)
We used near-infrared spectroscopy (NIRS) to study responses to speech and music on the auditory cortices of 13 healthy full-term newborn infants during natural sleep. The purpose of the study was to investigate the lateralization of speech and music responses at this stage of development. NIRS data was recorded from eight positions on both hemispheres simultaneously with electroencephalography, electrooculography, electrocardiography, pulse oximetry, and inclinometry. In 11 subjects, statistically significant (P < 0.02) oxygenated (HbO(2)) and total hemoglobin (HbT) responses were recorded. Both stimulus types elicited significant HbO(2) and HUT responses on both hemispheres in five subjects. Six of the 11 subjects had positive HbO(2) and HbT responses to both stimulus types, whereas one subject had negative responses. Mixed positive and negative responses were observed in four neonates. On both hemispheres, speech and music responses were significantly correlated (r = 0.64; P = 0.018 on the left hemisphere (LH) and r = 0.60; P = 0.029 on the right hemisphere (RH)). On the group level, the average response to the speech stimuli was statistically significantly greater than zero in the LH, whereas responses on the RH or to the music stimuli did not differ significantly from zero. This suggests a more coherent response to speech on the LH. However, significant differences in lateralization of the responses or mean response amplitudes of the two stimulus types were not observed on the group level. Hum Brain Mapp 31:595-603, 2010. (C) 2009 Wiley-Liss, Inc. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
auditory responses, near-infrared spectroscopy, functional laterality, brain imaging, neonate
in
Human Brain Mapping
volume
31
issue
4
pages
595 - 603
publisher
Wiley-Blackwell
external identifiers
  • wos:000276537800009
  • scopus:77949384626
ISSN
1065-9471
DOI
10.1002/hbm.20890
language
English
LU publication?
yes
id
86ded1e0-760b-4375-ad4b-0b31e2bdee1a (old id 1603912)
date added to LUP
2010-05-18 15:55:31
date last changed
2018-06-17 03:21:59
@article{86ded1e0-760b-4375-ad4b-0b31e2bdee1a,
  abstract     = {We used near-infrared spectroscopy (NIRS) to study responses to speech and music on the auditory cortices of 13 healthy full-term newborn infants during natural sleep. The purpose of the study was to investigate the lateralization of speech and music responses at this stage of development. NIRS data was recorded from eight positions on both hemispheres simultaneously with electroencephalography, electrooculography, electrocardiography, pulse oximetry, and inclinometry. In 11 subjects, statistically significant (P &lt; 0.02) oxygenated (HbO(2)) and total hemoglobin (HbT) responses were recorded. Both stimulus types elicited significant HbO(2) and HUT responses on both hemispheres in five subjects. Six of the 11 subjects had positive HbO(2) and HbT responses to both stimulus types, whereas one subject had negative responses. Mixed positive and negative responses were observed in four neonates. On both hemispheres, speech and music responses were significantly correlated (r = 0.64; P = 0.018 on the left hemisphere (LH) and r = 0.60; P = 0.029 on the right hemisphere (RH)). On the group level, the average response to the speech stimuli was statistically significantly greater than zero in the LH, whereas responses on the RH or to the music stimuli did not differ significantly from zero. This suggests a more coherent response to speech on the LH. However, significant differences in lateralization of the responses or mean response amplitudes of the two stimulus types were not observed on the group level. Hum Brain Mapp 31:595-603, 2010. (C) 2009 Wiley-Liss, Inc.},
  author       = {Kotilahti, Kalle and Nissila, Ilkka and Nasi, Tiina and Lipiainen, Lauri and Noponen, Tommi and Merilainen, Pekka and Huotilainen, Minna and Fellman, Vineta},
  issn         = {1065-9471},
  keyword      = {auditory responses,near-infrared spectroscopy,functional laterality,brain imaging,neonate},
  language     = {eng},
  number       = {4},
  pages        = {595--603},
  publisher    = {Wiley-Blackwell},
  series       = {Human Brain Mapping},
  title        = {Hemodynamic Responses to Speech and Music in Newborn Infants},
  url          = {http://dx.doi.org/10.1002/hbm.20890},
  volume       = {31},
  year         = {2010},
}