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Immuno-CoPS (conducting paper strips) for futuristic cost-effective cancer diagnostics

Kumar, Saurabh; Jagadeesan, Kishore LU ; Joshi, Amish G. and Sumana, Gajjala (2013) In RSC Advances 3(29). p.11846-11853
Abstract
The fabrication of cost-effective, rapid and specific paper based point-of-care (POC) diagnostics based on the principles of bio-recognition is currently at the vanguard of biomedical research, as it is playing a key role in early diagnosis and treatment, resulting in the inhibition of infection and reducing the mortality rate. In the present report, we demonstrate that biomolecules can be directly attached to a paper matrix covalently, by suitable modification of the paper matrices. A high conductivity is achieved and the porosity can be tailored and has been utilized for the quantitative estimation of bio-analytes. We prove the feasibility of our approach for the detection of cancer biomarkers in a wide detection range.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
RSC Advances
volume
3
issue
29
pages
11846 - 11853
publisher
Royal Society of Chemistry
external identifiers
  • wos:000321203900069
  • scopus:84879847750
ISSN
2046-2069
DOI
10.1039/c3ra40491a
language
English
LU publication?
yes
id
160c343d-a0d6-471c-b10d-e399963d37c9 (old id 3979390)
date added to LUP
2013-09-06 08:47:46
date last changed
2019-02-27 03:18:52
@article{160c343d-a0d6-471c-b10d-e399963d37c9,
  abstract     = {The fabrication of cost-effective, rapid and specific paper based point-of-care (POC) diagnostics based on the principles of bio-recognition is currently at the vanguard of biomedical research, as it is playing a key role in early diagnosis and treatment, resulting in the inhibition of infection and reducing the mortality rate. In the present report, we demonstrate that biomolecules can be directly attached to a paper matrix covalently, by suitable modification of the paper matrices. A high conductivity is achieved and the porosity can be tailored and has been utilized for the quantitative estimation of bio-analytes. We prove the feasibility of our approach for the detection of cancer biomarkers in a wide detection range.},
  author       = {Kumar, Saurabh and Jagadeesan, Kishore and Joshi, Amish G. and Sumana, Gajjala},
  issn         = {2046-2069},
  language     = {eng},
  number       = {29},
  pages        = {11846--11853},
  publisher    = {Royal Society of Chemistry},
  series       = {RSC Advances},
  title        = {Immuno-CoPS (conducting paper strips) for futuristic cost-effective cancer diagnostics},
  url          = {http://dx.doi.org/10.1039/c3ra40491a},
  volume       = {3},
  year         = {2013},
}