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High-frequency electrocardiogram as a supplement to standard 12-lead ischemia monitoring during reperfusion therapy of acute inferior myocardial infarction.

Pettersson, Jonas ; Wagner, Galen S ; Sörnmo, Leif ; Trägårdh, Elin LU ; Öhlin, Hans and Pahlm, Olle LU (2011) In Journal of Electrocardiology 44. p.11-17
Abstract
BACKGROUND: Resolution of ST-segment elevation in the electrocardiogram (ECG) is used as a reperfusion sign during thrombolytic therapy in acute myocardial infarction. Analysis of high-frequency QRS components (HF-QRS) might provide additional information. The study compares changes in HF-QRS (150-250 Hz) to ST-segment changes in the standard ECG during thrombolytic therapy. METHODS: Twelve patients receiving intravenous thrombolytic therapy were included. A continuous 12-lead ECG recording was acquired for 4 hours. RESULTS: After 1 hour of therapy, 3 patients showed ST-elevation resolution as well as an increase in HF-QRS. These changes in ST and HF-QRS occurred simultaneously. No other patient showed significant changes in ST or HF-QRS... (More)
BACKGROUND: Resolution of ST-segment elevation in the electrocardiogram (ECG) is used as a reperfusion sign during thrombolytic therapy in acute myocardial infarction. Analysis of high-frequency QRS components (HF-QRS) might provide additional information. The study compares changes in HF-QRS (150-250 Hz) to ST-segment changes in the standard ECG during thrombolytic therapy. METHODS: Twelve patients receiving intravenous thrombolytic therapy were included. A continuous 12-lead ECG recording was acquired for 4 hours. RESULTS: After 1 hour of therapy, 3 patients showed ST-elevation resolution as well as an increase in HF-QRS. These changes in ST and HF-QRS occurred simultaneously. No other patient showed significant changes in ST or HF-QRS after 1 hour. After 2 and 4 hours, there was less concordance between the standard and high-frequency ECGs. CONCLUSIONS: In patients with early ST-elevation resolution, the standard and high-frequency ECGs show similar results. Later changes are more disparate and may provide different clinical information. (Less)
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Electrocardiology
volume
44
pages
11 - 17
publisher
Elsevier
external identifiers
  • wos:000286021900003
  • pmid:20488451
  • scopus:78650420167
ISSN
1532-8430
DOI
10.1016/j.jelectrocard.2010.04.006
language
English
LU publication?
yes
id
7fb614dd-bd7a-417c-b948-c02e4559b0a9 (old id 1610086)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/20488451?dopt=Abstract
date added to LUP
2016-04-04 08:55:26
date last changed
2023-09-05 17:53:28
@article{7fb614dd-bd7a-417c-b948-c02e4559b0a9,
  abstract     = {{BACKGROUND: Resolution of ST-segment elevation in the electrocardiogram (ECG) is used as a reperfusion sign during thrombolytic therapy in acute myocardial infarction. Analysis of high-frequency QRS components (HF-QRS) might provide additional information. The study compares changes in HF-QRS (150-250 Hz) to ST-segment changes in the standard ECG during thrombolytic therapy. METHODS: Twelve patients receiving intravenous thrombolytic therapy were included. A continuous 12-lead ECG recording was acquired for 4 hours. RESULTS: After 1 hour of therapy, 3 patients showed ST-elevation resolution as well as an increase in HF-QRS. These changes in ST and HF-QRS occurred simultaneously. No other patient showed significant changes in ST or HF-QRS after 1 hour. After 2 and 4 hours, there was less concordance between the standard and high-frequency ECGs. CONCLUSIONS: In patients with early ST-elevation resolution, the standard and high-frequency ECGs show similar results. Later changes are more disparate and may provide different clinical information.}},
  author       = {{Pettersson, Jonas and Wagner, Galen S and Sörnmo, Leif and Trägårdh, Elin and Öhlin, Hans and Pahlm, Olle}},
  issn         = {{1532-8430}},
  language     = {{eng}},
  pages        = {{11--17}},
  publisher    = {{Elsevier}},
  series       = {{Journal of Electrocardiology}},
  title        = {{High-frequency electrocardiogram as a supplement to standard 12-lead ischemia monitoring during reperfusion therapy of acute inferior myocardial infarction.}},
  url          = {{https://lup.lub.lu.se/search/files/5210752/1638840.pdf}},
  doi          = {{10.1016/j.jelectrocard.2010.04.006}},
  volume       = {{44}},
  year         = {{2011}},
}