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High-frequency electrocardiogram as a supplement to standard 12-lead ischemia monitoring during reperfusion therapy of acute inferior myocardial infarction.

Pettersson, Jonas; Wagner, Galen S; Sörnmo, Leif; Trägårdh, Elin LU ; Öhlin, Hans and Pahlm, Olle LU (2011) In Journal of Electrocardiology 44. p.11-17
Abstract
BACKGROUND: Resolution of ST-segment elevation in the electrocardiogram (ECG) is used as a reperfusion sign during thrombolytic therapy in acute myocardial infarction. Analysis of high-frequency QRS components (HF-QRS) might provide additional information. The study compares changes in HF-QRS (150-250 Hz) to ST-segment changes in the standard ECG during thrombolytic therapy. METHODS: Twelve patients receiving intravenous thrombolytic therapy were included. A continuous 12-lead ECG recording was acquired for 4 hours. RESULTS: After 1 hour of therapy, 3 patients showed ST-elevation resolution as well as an increase in HF-QRS. These changes in ST and HF-QRS occurred simultaneously. No other patient showed significant changes in ST or HF-QRS... (More)
BACKGROUND: Resolution of ST-segment elevation in the electrocardiogram (ECG) is used as a reperfusion sign during thrombolytic therapy in acute myocardial infarction. Analysis of high-frequency QRS components (HF-QRS) might provide additional information. The study compares changes in HF-QRS (150-250 Hz) to ST-segment changes in the standard ECG during thrombolytic therapy. METHODS: Twelve patients receiving intravenous thrombolytic therapy were included. A continuous 12-lead ECG recording was acquired for 4 hours. RESULTS: After 1 hour of therapy, 3 patients showed ST-elevation resolution as well as an increase in HF-QRS. These changes in ST and HF-QRS occurred simultaneously. No other patient showed significant changes in ST or HF-QRS after 1 hour. After 2 and 4 hours, there was less concordance between the standard and high-frequency ECGs. CONCLUSIONS: In patients with early ST-elevation resolution, the standard and high-frequency ECGs show similar results. Later changes are more disparate and may provide different clinical information. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Electrocardiology
volume
44
pages
11 - 17
publisher
Elsevier
external identifiers
  • wos:000286021900003
  • pmid:20488451
  • scopus:78650420167
ISSN
1532-8430
DOI
10.1016/j.jelectrocard.2010.04.006
language
English
LU publication?
yes
id
7fb614dd-bd7a-417c-b948-c02e4559b0a9 (old id 1610086)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/20488451?dopt=Abstract
date added to LUP
2010-06-02 11:21:17
date last changed
2017-01-15 04:25:02
@article{7fb614dd-bd7a-417c-b948-c02e4559b0a9,
  abstract     = {BACKGROUND: Resolution of ST-segment elevation in the electrocardiogram (ECG) is used as a reperfusion sign during thrombolytic therapy in acute myocardial infarction. Analysis of high-frequency QRS components (HF-QRS) might provide additional information. The study compares changes in HF-QRS (150-250 Hz) to ST-segment changes in the standard ECG during thrombolytic therapy. METHODS: Twelve patients receiving intravenous thrombolytic therapy were included. A continuous 12-lead ECG recording was acquired for 4 hours. RESULTS: After 1 hour of therapy, 3 patients showed ST-elevation resolution as well as an increase in HF-QRS. These changes in ST and HF-QRS occurred simultaneously. No other patient showed significant changes in ST or HF-QRS after 1 hour. After 2 and 4 hours, there was less concordance between the standard and high-frequency ECGs. CONCLUSIONS: In patients with early ST-elevation resolution, the standard and high-frequency ECGs show similar results. Later changes are more disparate and may provide different clinical information.},
  author       = {Pettersson, Jonas and Wagner, Galen S and Sörnmo, Leif and Trägårdh, Elin and Öhlin, Hans and Pahlm, Olle},
  issn         = {1532-8430},
  language     = {eng},
  pages        = {11--17},
  publisher    = {Elsevier},
  series       = {Journal of Electrocardiology},
  title        = {High-frequency electrocardiogram as a supplement to standard 12-lead ischemia monitoring during reperfusion therapy of acute inferior myocardial infarction.},
  url          = {http://dx.doi.org/10.1016/j.jelectrocard.2010.04.006},
  volume       = {44},
  year         = {2011},
}