Aktivt induceret hypotermi efter svaer traumatisk hjerneskade.
(2010) In Ugeskrift for Læger 172(19). p.1437-1440- Abstract
- A Cochrane metaanalysis and a study performed on children have recently confirmed that therapeutic hypothermia does not improve outcome after severe traumatic brain injury (TBI). TBI is not comparable to a short episode of global ischemia, where therapeutic hypothermia has been shown to improve outcome. The difference may be explained by the fact that hypothermia-induced stress after a traumatic brain injury reduces cerebral perfusion in the penumbra zone, where local circulation is already reduced. Thus, to date there is no indication for therapeutic hypothermia in TBI patients.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1610245
- author
- Grände, Per-Olof LU ; Welling, Karen-Lise ; Eskesen, Vagn and Romner, Bertil LU
- organization
- alternative title
- Actively induced hypothermia following severe traumatic brain injury
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Ugeskrift for Læger
- volume
- 172
- issue
- 19
- pages
- 1437 - 1440
- publisher
- Almindelige Danske Laegeforening
- external identifiers
-
- pmid:20470652
- scopus:77954931163
- ISSN
- 0041-5782
- language
- Danish
- LU publication?
- yes
- id
- a7e2ce45-849f-42f5-83d1-2207c4f31d12 (old id 1610245)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/20470652?dopt=Abstract
- date added to LUP
- 2016-04-04 09:12:43
- date last changed
- 2025-01-06 05:28:41
@article{a7e2ce45-849f-42f5-83d1-2207c4f31d12,
abstract = {{A Cochrane metaanalysis and a study performed on children have recently confirmed that therapeutic hypothermia does not improve outcome after severe traumatic brain injury (TBI). TBI is not comparable to a short episode of global ischemia, where therapeutic hypothermia has been shown to improve outcome. The difference may be explained by the fact that hypothermia-induced stress after a traumatic brain injury reduces cerebral perfusion in the penumbra zone, where local circulation is already reduced. Thus, to date there is no indication for therapeutic hypothermia in TBI patients.}},
author = {{Grände, Per-Olof and Welling, Karen-Lise and Eskesen, Vagn and Romner, Bertil}},
issn = {{0041-5782}},
language = {{dan}},
number = {{19}},
pages = {{1437--1440}},
publisher = {{Almindelige Danske Laegeforening}},
series = {{Ugeskrift for Læger}},
title = {{Aktivt induceret hypotermi efter svaer traumatisk hjerneskade.}},
url = {{http://www.ncbi.nlm.nih.gov/pubmed/20470652?dopt=Abstract}},
volume = {{172}},
year = {{2010}},
}