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Prevention and Management of Complications Following Radical Cystectomy for Bladder Cancer

Lawrentschuk, Nathan; Colombo, Renzo; Hakenberg, Oliver W.; Lerner, Seth P.; Månsson, Wiking LU ; Sagalowsky, Arthur and Wirth, Manfred P. (2010) In European Urology 57(6). p.983-1001
Abstract
Context: This review focuses on the prevention and management of complications following radical cystectomy (RC) for bladder cancer (BCa). Objective: We review the current literature and perform an analysis of the frequency, treatment, and prevention of complications related to RC for BCa. Evidence acquisition: A Medline search was conducted to identify original articles, reviews, and editorials addressing the relationship between RC and short- and long-term complications. Series examined were published within the past decade. Large series reported on multiple occasions (Lee [1], Meyer [2], and Chang and Cookson [3]) with the same cohorts are recorded only once. Quality of life (QoL) and sexual function were excluded. Evidence synthesis:... (More)
Context: This review focuses on the prevention and management of complications following radical cystectomy (RC) for bladder cancer (BCa). Objective: We review the current literature and perform an analysis of the frequency, treatment, and prevention of complications related to RC for BCa. Evidence acquisition: A Medline search was conducted to identify original articles, reviews, and editorials addressing the relationship between RC and short- and long-term complications. Series examined were published within the past decade. Large series reported on multiple occasions (Lee [1], Meyer [2], and Chang and Cookson [3]) with the same cohorts are recorded only once. Quality of life (QoL) and sexual function were excluded. Evidence synthesis: The literature regarding prophylaxis, prevention, and treatment of complications of RC in general is retrospective, not standardised. In general, it is of poor quality when it comes to evidence and is thus difficult to synthesise. Conclusions: Progress has been made in reducing mortality and preventing complications of RC. Postoperative morbidity remains high, partly because of the complexity of the procedures. The issues of surgical volume and standardised prospective reporting of RC morbidity to create evidence-based guidelines are essential for further reducing morbidity and improving patients' QoL. (C) 2010 European Association of Urology. Published by Elsevier B. V. All rights reserved. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adverse effects, Bladder carcinoma, Cystectomy, Urology, Surgery, Review
in
European Urology
volume
57
issue
6
pages
983 - 1001
publisher
Elsevier
external identifiers
  • wos:000277245800015
  • scopus:77951620888
ISSN
1873-7560
DOI
10.1016/j.eururo.2010.02.024
language
English
LU publication?
yes
id
e9f6dd56-a98d-4943-94aa-295b4bcb421d (old id 1619444)
date added to LUP
2010-06-18 13:07:48
date last changed
2018-06-10 04:24:38
@article{e9f6dd56-a98d-4943-94aa-295b4bcb421d,
  abstract     = {Context: This review focuses on the prevention and management of complications following radical cystectomy (RC) for bladder cancer (BCa). Objective: We review the current literature and perform an analysis of the frequency, treatment, and prevention of complications related to RC for BCa. Evidence acquisition: A Medline search was conducted to identify original articles, reviews, and editorials addressing the relationship between RC and short- and long-term complications. Series examined were published within the past decade. Large series reported on multiple occasions (Lee [1], Meyer [2], and Chang and Cookson [3]) with the same cohorts are recorded only once. Quality of life (QoL) and sexual function were excluded. Evidence synthesis: The literature regarding prophylaxis, prevention, and treatment of complications of RC in general is retrospective, not standardised. In general, it is of poor quality when it comes to evidence and is thus difficult to synthesise. Conclusions: Progress has been made in reducing mortality and preventing complications of RC. Postoperative morbidity remains high, partly because of the complexity of the procedures. The issues of surgical volume and standardised prospective reporting of RC morbidity to create evidence-based guidelines are essential for further reducing morbidity and improving patients' QoL. (C) 2010 European Association of Urology. Published by Elsevier B. V. All rights reserved.},
  author       = {Lawrentschuk, Nathan and Colombo, Renzo and Hakenberg, Oliver W. and Lerner, Seth P. and Månsson, Wiking and Sagalowsky, Arthur and Wirth, Manfred P.},
  issn         = {1873-7560},
  keyword      = {Adverse effects,Bladder carcinoma,Cystectomy,Urology,Surgery,Review},
  language     = {eng},
  number       = {6},
  pages        = {983--1001},
  publisher    = {Elsevier},
  series       = {European Urology},
  title        = {Prevention and Management of Complications Following Radical Cystectomy for Bladder Cancer},
  url          = {http://dx.doi.org/10.1016/j.eururo.2010.02.024},
  volume       = {57},
  year         = {2010},
}