Advanced

Endometriomas: their ultrasound characteristics

Van Holsbeke, C.; Van Calster, B.; Guerriero, S.; Savelli, L.; Paladini, D.; Lissoni, A. A.; Czekierdowski, A.; Fischerova, D.; Zhang, J. and Mestdagh, G., et al. (2010) In Ultrasound in Obstetrics & Gynecology 35(6). p.730-740
Abstract
Objectives To describe the ultrasound characteristics of endometriomas in pre- and postmenopausal patients and to develop rules that characterize endometriomas. Methods All patients included in the International Ovarian Tumor Analysis (IOTA) studies were used in our analysis. Patients with an adnexal mass were scanned by experienced sonologists using a standardized research protocol. The gold standard was the histology of the surgically removed adnexal mass. The gray-scale and Doppler ultrasound characteristics of the endometriomas were compared with those of other benign and malignant masses. Based on decision-tree analysis, the existing literature and clinical experience, ultrasound rules for the detection of endometriomas were created... (More)
Objectives To describe the ultrasound characteristics of endometriomas in pre- and postmenopausal patients and to develop rules that characterize endometriomas. Methods All patients included in the International Ovarian Tumor Analysis (IOTA) studies were used in our analysis. Patients with an adnexal mass were scanned by experienced sonologists using a standardized research protocol. The gold standard was the histology of the surgically removed adnexal mass. The gray-scale and Doppler ultrasound characteristics of the endometriomas were compared with those of other benign and malignant masses. Based on decision-tree analysis, the existing literature and clinical experience, ultrasound rules for the detection of endometriomas were created and evaluated. Results Of all 3511 patients included in the IOTA studies, 713 (20%) had endometriomas. Fifty-one per cent of the endometriomas were unilocular cysts with ground glass echogenicity of the cyst fluid. These characteristics were found less often among other benign tumors or malignancies, or among the small set of endometriomas (4%) that were found in postmenopausal patients. Based on the decision-tree analysis, the optimal rule to detect endometriomas was an adnexal mass in a premenopausal patient with ground glass echogenicity of the cyst fluid, one to four locules and no papillations with detectable blood flow'. Based on clinical considerations, the following rule: 'premenopausal status, ground glass echogenicity of the cyst fluid, one to four locules and no solid parts' seems preferable. Conclusions Several rules had a good ability to characterize endometriomas. The ultrasound characteristics of endometriomas differ between pre- and postmenopausal patients. Masses in postmenopausal women whose cystic contents have a ground glass appearance have a high risk of malignancy. Copyright (C) 2010 ISUOG. Published by John Wiley & Sons, Ltd. (Less)
Please use this url to cite or link to this publication:
author
, et al. (More)
(Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
ovarian neoplasms, endometrioma, endometriosis, ultrasonography
in
Ultrasound in Obstetrics & Gynecology
volume
35
issue
6
pages
730 - 740
publisher
John Wiley & Sons
external identifiers
  • wos:000279123400014
  • scopus:77953561372
ISSN
1469-0705
DOI
10.1002/uog.7668
language
English
LU publication?
yes
id
2238a857-2dd1-434c-90d6-5fa4d5567a8c (old id 1629417)
date added to LUP
2010-07-22 09:09:52
date last changed
2018-07-22 03:43:31
@article{2238a857-2dd1-434c-90d6-5fa4d5567a8c,
  abstract     = {Objectives To describe the ultrasound characteristics of endometriomas in pre- and postmenopausal patients and to develop rules that characterize endometriomas. Methods All patients included in the International Ovarian Tumor Analysis (IOTA) studies were used in our analysis. Patients with an adnexal mass were scanned by experienced sonologists using a standardized research protocol. The gold standard was the histology of the surgically removed adnexal mass. The gray-scale and Doppler ultrasound characteristics of the endometriomas were compared with those of other benign and malignant masses. Based on decision-tree analysis, the existing literature and clinical experience, ultrasound rules for the detection of endometriomas were created and evaluated. Results Of all 3511 patients included in the IOTA studies, 713 (20%) had endometriomas. Fifty-one per cent of the endometriomas were unilocular cysts with ground glass echogenicity of the cyst fluid. These characteristics were found less often among other benign tumors or malignancies, or among the small set of endometriomas (4%) that were found in postmenopausal patients. Based on the decision-tree analysis, the optimal rule to detect endometriomas was an adnexal mass in a premenopausal patient with ground glass echogenicity of the cyst fluid, one to four locules and no papillations with detectable blood flow'. Based on clinical considerations, the following rule: 'premenopausal status, ground glass echogenicity of the cyst fluid, one to four locules and no solid parts' seems preferable. Conclusions Several rules had a good ability to characterize endometriomas. The ultrasound characteristics of endometriomas differ between pre- and postmenopausal patients. Masses in postmenopausal women whose cystic contents have a ground glass appearance have a high risk of malignancy. Copyright (C) 2010 ISUOG. Published by John Wiley & Sons, Ltd.},
  author       = {Van Holsbeke, C. and Van Calster, B. and Guerriero, S. and Savelli, L. and Paladini, D. and Lissoni, A. A. and Czekierdowski, A. and Fischerova, D. and Zhang, J. and Mestdagh, G. and Testa, A. C. and Bourne, T. and Valentin, Lil and Timmerman, D.},
  issn         = {1469-0705},
  keyword      = {ovarian neoplasms,endometrioma,endometriosis,ultrasonography},
  language     = {eng},
  number       = {6},
  pages        = {730--740},
  publisher    = {John Wiley & Sons},
  series       = {Ultrasound in Obstetrics & Gynecology},
  title        = {Endometriomas: their ultrasound characteristics},
  url          = {http://dx.doi.org/10.1002/uog.7668},
  volume       = {35},
  year         = {2010},
}