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Considerations in the laboratory assessment of haemostasis

McCraw, A.; Hillarp, Andreas LU and Echenagucia, M. (2010) In Haemophilia 16(s5). p.74-78
Abstract
This review outlines a number of key issues when performing laboratory testing of homeostasis. The effect pre-analytical variables have on the reliability and consistency of screening tests is often forgotten due to a lack of understanding and awareness. This can be improved through educating healthcare professionals who are involved in taking blood for assessment. Recent advances in coagulation testing have not enabled laboratories to replace the Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) screening tests with more advanced assays and they continue to play an important role with the advantage of being easily automated. However, there are many analysers on the market, each with varying sensitivity to coagulation... (More)
This review outlines a number of key issues when performing laboratory testing of homeostasis. The effect pre-analytical variables have on the reliability and consistency of screening tests is often forgotten due to a lack of understanding and awareness. This can be improved through educating healthcare professionals who are involved in taking blood for assessment. Recent advances in coagulation testing have not enabled laboratories to replace the Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) screening tests with more advanced assays and they continue to play an important role with the advantage of being easily automated. However, there are many analysers on the market, each with varying sensitivity to coagulation defects and it is important to keep this in mind when interpreting results. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
coagulation analyses, APTT, Pre-analytical variables
in
Haemophilia
volume
16
issue
s5
pages
74 - 78
publisher
Federation of European Neuroscience Societies and Blackwell Publishing Ltd
external identifiers
  • wos:000279076100012
  • scopus:77955015968
ISSN
1351-8216
DOI
10.1111/j.1365-2516.2010.02302.x
language
English
LU publication?
yes
id
4b9cddd9-d420-497a-943d-8dea4fd61a61 (old id 1630194)
date added to LUP
2010-07-22 15:42:38
date last changed
2018-05-29 10:08:17
@article{4b9cddd9-d420-497a-943d-8dea4fd61a61,
  abstract     = {This review outlines a number of key issues when performing laboratory testing of homeostasis. The effect pre-analytical variables have on the reliability and consistency of screening tests is often forgotten due to a lack of understanding and awareness. This can be improved through educating healthcare professionals who are involved in taking blood for assessment. Recent advances in coagulation testing have not enabled laboratories to replace the Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) screening tests with more advanced assays and they continue to play an important role with the advantage of being easily automated. However, there are many analysers on the market, each with varying sensitivity to coagulation defects and it is important to keep this in mind when interpreting results.},
  author       = {McCraw, A. and Hillarp, Andreas and Echenagucia, M.},
  issn         = {1351-8216},
  keyword      = {coagulation analyses,APTT,Pre-analytical variables},
  language     = {eng},
  number       = {s5},
  pages        = {74--78},
  publisher    = {Federation of European Neuroscience Societies and Blackwell Publishing Ltd},
  series       = {Haemophilia},
  title        = {Considerations in the laboratory assessment of haemostasis},
  url          = {http://dx.doi.org/10.1111/j.1365-2516.2010.02302.x},
  volume       = {16},
  year         = {2010},
}