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Prediction of Intradialytic Hypotension Using Photoplethysmography

Solem, Kristian LU ; Olde, Bo and Sörnmo, Leif LU (2010) In IEEE Transactions on Biomedical Engineering 57(7). p.1611-1619
Abstract
Intradialytic hypotension is the most common acute complication during conventional hemodialysis treatment. Prediction of such events is highly desirable in clinical routine for prevention. This paper presents a novel prediction method of acute symptomatic hypotension in which the photoplethysmographic signal is analyzed with respect to changes in amplitude, reflecting vasoconstriction, and cardiac output. The method is based on a statistical model in which the noise is assumed to have Laplacian amplitude distribution. The performance is evaluated on 11 hypotension-prone patients who underwent hemodialysis treatment, resulting in seven events with acute symptomatic hypotension and 17 without. The photoplethysmographic signal was... (More)
Intradialytic hypotension is the most common acute complication during conventional hemodialysis treatment. Prediction of such events is highly desirable in clinical routine for prevention. This paper presents a novel prediction method of acute symptomatic hypotension in which the photoplethysmographic signal is analyzed with respect to changes in amplitude, reflecting vasoconstriction, and cardiac output. The method is based on a statistical model in which the noise is assumed to have Laplacian amplitude distribution. The performance is evaluated on 11 hypotension-prone patients who underwent hemodialysis treatment, resulting in seven events with acute symptomatic hypotension and 17 without. The photoplethysmographic signal was continuously acquired during treatment as was information on blood pressure and oxygen saturation. Using leave-one-out cross validation, the proposed method predicted six out of seven hypotensive events, while producing 1 false prediction out of 17 possible. The performance was achieved when the prediction threshold was chosen to be in the range 57%-65% of the photoplethysmographic envelope at treatment onset. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
signal, pulse oximetry, Hemodialysis, intradialytic hypotension, vasoconstriction, processing
in
IEEE Transactions on Biomedical Engineering
volume
57
issue
7
pages
1611 - 1619
publisher
IEEE--Institute of Electrical and Electronics Engineers Inc.
external identifiers
  • wos:000278811900009
  • scopus:77953742912
ISSN
0018-9294
DOI
10.1109/TBME.2010.2042170
language
English
LU publication?
yes
id
264c98ce-ae4c-4aca-9692-dd16faca7aea (old id 1630472)
date added to LUP
2010-07-21 15:19:52
date last changed
2018-05-29 12:12:55
@article{264c98ce-ae4c-4aca-9692-dd16faca7aea,
  abstract     = {Intradialytic hypotension is the most common acute complication during conventional hemodialysis treatment. Prediction of such events is highly desirable in clinical routine for prevention. This paper presents a novel prediction method of acute symptomatic hypotension in which the photoplethysmographic signal is analyzed with respect to changes in amplitude, reflecting vasoconstriction, and cardiac output. The method is based on a statistical model in which the noise is assumed to have Laplacian amplitude distribution. The performance is evaluated on 11 hypotension-prone patients who underwent hemodialysis treatment, resulting in seven events with acute symptomatic hypotension and 17 without. The photoplethysmographic signal was continuously acquired during treatment as was information on blood pressure and oxygen saturation. Using leave-one-out cross validation, the proposed method predicted six out of seven hypotensive events, while producing 1 false prediction out of 17 possible. The performance was achieved when the prediction threshold was chosen to be in the range 57%-65% of the photoplethysmographic envelope at treatment onset.},
  author       = {Solem, Kristian and Olde, Bo and Sörnmo, Leif},
  issn         = {0018-9294},
  keyword      = {signal,pulse oximetry,Hemodialysis,intradialytic hypotension,vasoconstriction,processing},
  language     = {eng},
  number       = {7},
  pages        = {1611--1619},
  publisher    = {IEEE--Institute of Electrical and Electronics Engineers Inc.},
  series       = {IEEE Transactions on Biomedical Engineering},
  title        = {Prediction of Intradialytic Hypotension Using Photoplethysmography},
  url          = {http://dx.doi.org/10.1109/TBME.2010.2042170},
  volume       = {57},
  year         = {2010},
}