Variation in the amount of petrolatum preparation applied at patch testing.
(2007) In Contact Dermatitis 56(1). p.38-42- Abstract
- The elicitation of a positive patch test reaction in a given individual depends upon the dose of the sensitizer applied, the patch test technique and the occlusion time. The dose is determined by the concentration and volume/amount of test preparation applied. If the same amount/volume of a test preparation is applied all the time with the same test technique (same area of skin) and occlusion time, it is appropriate to use concentration as a dose parameter. Most contact sensitizers are incorporated in petrolatum (pet.). With pet. as vehicle, it is impossible to repeatedly apply an exact volume/amount. This study was performed to investigate the inter- and intra-individual variation of pet. preparation applied at patch testing by 3... (More)
- The elicitation of a positive patch test reaction in a given individual depends upon the dose of the sensitizer applied, the patch test technique and the occlusion time. The dose is determined by the concentration and volume/amount of test preparation applied. If the same amount/volume of a test preparation is applied all the time with the same test technique (same area of skin) and occlusion time, it is appropriate to use concentration as a dose parameter. Most contact sensitizers are incorporated in petrolatum (pet.). With pet. as vehicle, it is impossible to repeatedly apply an exact volume/amount. This study was performed to investigate the inter- and intra-individual variation of pet. preparation applied at patch testing by 3 technicians. Weighing demonstrated that the 3 technicians had about the same precision in their pet. application. The investigation demonstrates that there is both an inter-individual (statistically significant) and intra-individual variation in the amounts of pet. applied at patch testing for the 3 technicians. Presently, there is no recommendation on what amount of pet. preparation to apply, which merits a decision to be taken based on thorough investigations on the appropriate volumes of pet. preparation to be applied in various patch test systems. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/163910
- author
- Bruze, Magnus LU ; Frick-Engfeldt, Malin ; Gruvberger, Birgitta LU and Isaksson, Marléne LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- weighing, standard series, intra-individual, inter-individual, (R), Finn Chamber, dose/area, allergic contact dermatitis, contact allergy
- in
- Contact Dermatitis
- volume
- 56
- issue
- 1
- pages
- 38 - 42
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000242658800008
- scopus:33845520814
- ISSN
- 0105-1873
- DOI
- 10.1111/j.1600-0536.2007.00985.x
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Occupational and Environmental Dermatology Unit (013241310), Pediatrics/Urology/Gynecology/Endocrinology (013240400)
- id
- 3a49df0a-676d-4d93-a1c6-8cf897677952 (old id 163910)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17177708&dopt=Abstract
- date added to LUP
- 2016-04-01 12:11:41
- date last changed
- 2022-03-21 00:50:12
@article{3a49df0a-676d-4d93-a1c6-8cf897677952,
abstract = {{The elicitation of a positive patch test reaction in a given individual depends upon the dose of the sensitizer applied, the patch test technique and the occlusion time. The dose is determined by the concentration and volume/amount of test preparation applied. If the same amount/volume of a test preparation is applied all the time with the same test technique (same area of skin) and occlusion time, it is appropriate to use concentration as a dose parameter. Most contact sensitizers are incorporated in petrolatum (pet.). With pet. as vehicle, it is impossible to repeatedly apply an exact volume/amount. This study was performed to investigate the inter- and intra-individual variation of pet. preparation applied at patch testing by 3 technicians. Weighing demonstrated that the 3 technicians had about the same precision in their pet. application. The investigation demonstrates that there is both an inter-individual (statistically significant) and intra-individual variation in the amounts of pet. applied at patch testing for the 3 technicians. Presently, there is no recommendation on what amount of pet. preparation to apply, which merits a decision to be taken based on thorough investigations on the appropriate volumes of pet. preparation to be applied in various patch test systems.}},
author = {{Bruze, Magnus and Frick-Engfeldt, Malin and Gruvberger, Birgitta and Isaksson, Marléne}},
issn = {{0105-1873}},
keywords = {{weighing; standard series; intra-individual; inter-individual; (R); Finn Chamber; dose/area; allergic contact dermatitis; contact allergy}},
language = {{eng}},
number = {{1}},
pages = {{38--42}},
publisher = {{Wiley-Blackwell}},
series = {{Contact Dermatitis}},
title = {{Variation in the amount of petrolatum preparation applied at patch testing.}},
url = {{https://lup.lub.lu.se/search/files/2821642/625801.pdf}},
doi = {{10.1111/j.1600-0536.2007.00985.x}},
volume = {{56}},
year = {{2007}},
}