Advanced

The Quantitative Relationship between Longitudinal and Radial Function in Left, Right and Total Heart Pumping in Humans.

Carlsson, Marcus LU ; Ugander, Martin LU ; Heiberg, Einar LU and Arheden, Håkan LU (2007) In American Journal of Physiology: Heart and Circulatory Physiology 293(1). p.636-644
Abstract
The total heart volume variation (THVV) during systole has been proposed to be caused by radial function of the ventricles, but definitive data for both ventricles have not been presented. Furthermore, the right ventricle (RV) has been suggested to have a greater longitudinal pumping component than the left ventricle (LV). Therefore, we aimed to compare the stroke volume (SV) generated by radial function to the volume variation of the left, right, and total heart. To do this, we also needed to develop a new method for measuring the contribution of the longitudinal atrioventricular plane displacement (AVPD) to the RVSV (RVSVAVPD). For our study, 11 volunteers underwent cine MRI in the short- and long-axis planes and MRI flow measurement in... (More)
The total heart volume variation (THVV) during systole has been proposed to be caused by radial function of the ventricles, but definitive data for both ventricles have not been presented. Furthermore, the right ventricle (RV) has been suggested to have a greater longitudinal pumping component than the left ventricle (LV). Therefore, we aimed to compare the stroke volume (SV) generated by radial function to the volume variation of the left, right, and total heart. To do this, we also needed to develop a new method for measuring the contribution of the longitudinal atrioventricular plane displacement (AVPD) to the RVSV (RVSVAVPD). For our study, 11 volunteers underwent cine MRI in the short- and long-axis planes and MRI flow measurement in all vessels leading to and from the heart. The left, right, and total heart showed correlations between volume variation from flow measurements and radial function calculated as SV minus the longitudinal function (r = 0.81, P < 0.01; r = 0.80, P < 0.01; and r = 0.92, P < 0.001, respectively). Compared with the LV, the RV had a greater AVPD (23.4 +/- 0.8 vs. 16.4 +/- 0.5 mm), center of volume movement (13.0 +/- 0.7 vs. 7.8 +/- 0.4 mm), and, RVSVAVPD (82 +/- 2% vs. 60 +/- 2%) (P < 0.001 for all). We found that THVV is predominantly caused by radial function of the ventricles. Longitudinal AVPD accounts for similar to 80% of the RVSV, compared with similar to 60% for the LVSV. This difference explains the larger portion of THVV found on the left side of the heart. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
myocardial contraction, magnetic resonance imaging, physiology, ventricles, volume, cardiac
in
American Journal of Physiology: Heart and Circulatory Physiology
volume
293
issue
1
pages
636 - 644
publisher
American Physiological Society
external identifiers
  • wos:000247968800077
  • scopus:34547113317
ISSN
1522-1539
DOI
10.1152/ajpheart.01376.2006
language
English
LU publication?
yes
id
322c7324-5264-40ad-b423-95438ecb8d8d (old id 165628)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17307988&dopt=Abstract
date added to LUP
2007-07-23 08:01:46
date last changed
2017-10-29 03:41:05
@article{322c7324-5264-40ad-b423-95438ecb8d8d,
  abstract     = {The total heart volume variation (THVV) during systole has been proposed to be caused by radial function of the ventricles, but definitive data for both ventricles have not been presented. Furthermore, the right ventricle (RV) has been suggested to have a greater longitudinal pumping component than the left ventricle (LV). Therefore, we aimed to compare the stroke volume (SV) generated by radial function to the volume variation of the left, right, and total heart. To do this, we also needed to develop a new method for measuring the contribution of the longitudinal atrioventricular plane displacement (AVPD) to the RVSV (RVSVAVPD). For our study, 11 volunteers underwent cine MRI in the short- and long-axis planes and MRI flow measurement in all vessels leading to and from the heart. The left, right, and total heart showed correlations between volume variation from flow measurements and radial function calculated as SV minus the longitudinal function (r = 0.81, P &lt; 0.01; r = 0.80, P &lt; 0.01; and r = 0.92, P &lt; 0.001, respectively). Compared with the LV, the RV had a greater AVPD (23.4 +/- 0.8 vs. 16.4 +/- 0.5 mm), center of volume movement (13.0 +/- 0.7 vs. 7.8 +/- 0.4 mm), and, RVSVAVPD (82 +/- 2% vs. 60 +/- 2%) (P &lt; 0.001 for all). We found that THVV is predominantly caused by radial function of the ventricles. Longitudinal AVPD accounts for similar to 80% of the RVSV, compared with similar to 60% for the LVSV. This difference explains the larger portion of THVV found on the left side of the heart.},
  author       = {Carlsson, Marcus and Ugander, Martin and Heiberg, Einar and Arheden, Håkan},
  issn         = {1522-1539},
  keyword      = {myocardial contraction,magnetic resonance imaging,physiology,ventricles,volume,cardiac},
  language     = {eng},
  number       = {1},
  pages        = {636--644},
  publisher    = {American Physiological Society},
  series       = {American Journal of Physiology: Heart and Circulatory Physiology},
  title        = {The Quantitative Relationship between Longitudinal and Radial Function in Left, Right and Total Heart Pumping in Humans.},
  url          = {http://dx.doi.org/10.1152/ajpheart.01376.2006},
  volume       = {293},
  year         = {2007},
}