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The long-term course of depressive disorders in the Lundby Study.

Mattisson, Cecilia LU ; Bogren, Mats LU ; Horstmann, Vibeke LU ; Munk-Jorgensen, Povl and Nettelbladt, Per LU (2007) In Psychological Medicine 37(6). p.883-891
Abstract
Background. The Lundby Study is a longitudinal cohort study on a geographically defined population consisting of 3563 subjects. Information about episodes of different disorders was collected during field investigations in 1947, 1957, 1972 and in 1997. Interviews were carried out about current health and past episodes since the last investigation; for all subjects information was also collected from registers, case-notes and key informants. This paper describes the course and outcome of 344 subjects who had their first onset of depression during the follow-up. Method. In this study individuals who had experienced their first episode of depression were followed up. Their course was studied with regard to recurrence of depression related to... (More)
Background. The Lundby Study is a longitudinal cohort study on a geographically defined population consisting of 3563 subjects. Information about episodes of different disorders was collected during field investigations in 1947, 1957, 1972 and in 1997. Interviews were carried out about current health and past episodes since the last investigation; for all subjects information was also collected from registers, case-notes and key informants. This paper describes the course and outcome of 344 subjects who had their first onset of depression during the follow-up. Method. In this study individuals who had experienced their first episode of depression were followed up. Their course was studied with regard to recurrence of depression related to duration of follow-up, transition to other psychiatric disorders including alcohol disorders, as well as incidence and risk factors of suicide. Results. Median age at first onset of depression was around 35 years for individuals followed up for 30-49 years. The recurrence rate was about 40% and varied from 17% to 76% depending on length of follow-up. Transition to diagnoses other than depression was registered in 21% of the total sample, alcohol disorders in 7% and bipolar disorder in 2%. Five per cent committed suicide; male gender and severity of depression were significant risk factors. Conclusion. The low rates of recurrence and suicide suggest a better prognosis for community samples than for in- and out-patient samples. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Psychological Medicine
volume
37
issue
6
pages
883 - 891
publisher
Cambridge University Press
external identifiers
  • wos:000247050000011
  • scopus:34248577306
ISSN
1469-8978
DOI
10.1017/S0033291707000074
language
English
LU publication?
yes
id
24e26327-8126-4411-8918-6791e0486bc7 (old id 165652)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17306047&dopt=Abstract
date added to LUP
2007-07-16 13:03:28
date last changed
2017-09-17 04:52:26
@article{24e26327-8126-4411-8918-6791e0486bc7,
  abstract     = {Background. The Lundby Study is a longitudinal cohort study on a geographically defined population consisting of 3563 subjects. Information about episodes of different disorders was collected during field investigations in 1947, 1957, 1972 and in 1997. Interviews were carried out about current health and past episodes since the last investigation; for all subjects information was also collected from registers, case-notes and key informants. This paper describes the course and outcome of 344 subjects who had their first onset of depression during the follow-up. Method. In this study individuals who had experienced their first episode of depression were followed up. Their course was studied with regard to recurrence of depression related to duration of follow-up, transition to other psychiatric disorders including alcohol disorders, as well as incidence and risk factors of suicide. Results. Median age at first onset of depression was around 35 years for individuals followed up for 30-49 years. The recurrence rate was about 40% and varied from 17% to 76% depending on length of follow-up. Transition to diagnoses other than depression was registered in 21% of the total sample, alcohol disorders in 7% and bipolar disorder in 2%. Five per cent committed suicide; male gender and severity of depression were significant risk factors. Conclusion. The low rates of recurrence and suicide suggest a better prognosis for community samples than for in- and out-patient samples.},
  author       = {Mattisson, Cecilia and Bogren, Mats and Horstmann, Vibeke and Munk-Jorgensen, Povl and Nettelbladt, Per},
  issn         = {1469-8978},
  language     = {eng},
  number       = {6},
  pages        = {883--891},
  publisher    = {Cambridge University Press},
  series       = {Psychological Medicine},
  title        = {The long-term course of depressive disorders in the Lundby Study.},
  url          = {http://dx.doi.org/10.1017/S0033291707000074},
  volume       = {37},
  year         = {2007},
}