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Negative pressure wound therapy for post-sternotomy mediastinitis reduces mortality rate and sternal re-infection rate compared to conventional treatment

Petzina, Rainer; Hoffmann, Julia; Navasardyan, Artashes; Malmsjö, Malin LU ; Stamm, Christof; Unbehaun, Axel and Hetzer, Roland (2010) 23rd Annual Meeting of the European-Association-for-Cardio-Thoracic-Surgery In European Journal of Cardio-Thoracic Surgery 38(1). p.110-113
Abstract
Objective: Negative pressure wound therapy (NPWT) is a recently introduced treatment modality for post-sternotomy mediastinitis. The aim of this study was to compare the mortality rate, the sternal re-infection rate and the length of hospital stay in patients with post-sternotomy mediastinitis after NPWT and conventional treatment. Methods: We retrospectively analysed 118 patients with post-sternotomy mediastinitis after cardiac surgery. One group of 69 patients was treated with NPWT and the other group of 49 patients with conventional therapy. Results: There were no major differences between the two groups concerning preoperative data (EuroScore) or primary cardiac surgery (mainly coronary artery bypass grafting). NPWT therapy was found... (More)
Objective: Negative pressure wound therapy (NPWT) is a recently introduced treatment modality for post-sternotomy mediastinitis. The aim of this study was to compare the mortality rate, the sternal re-infection rate and the length of hospital stay in patients with post-sternotomy mediastinitis after NPWT and conventional treatment. Methods: We retrospectively analysed 118 patients with post-sternotomy mediastinitis after cardiac surgery. One group of 69 patients was treated with NPWT and the other group of 49 patients with conventional therapy. Results: There were no major differences between the two groups concerning preoperative data (EuroScore) or primary cardiac surgery (mainly coronary artery bypass grafting). NPWT therapy was found to reduce mortality rate (P = 0.005) and sternal re-infection rate (P = 0.008) compared with conventional treatment and tended to lead to a shorter length of hospital stay (P = 0.08). Conclusions: NPWT for post-sternotomy mediastinitis demonstrates encouraging clinical results with a reduction of the mortality rate and the sternal re-infection rate compared with conventional treatment. The results support NPWT as the first-line treatment for deep sternal wound infections. (C) 2010 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Wound healing, Mediastinal infection, Cardiac surgery
in
European Journal of Cardio-Thoracic Surgery
volume
38
issue
1
pages
110 - 113
publisher
Elsevier
conference name
23rd Annual Meeting of the European-Association-for-Cardio-Thoracic-Surgery
external identifiers
  • wos:000279744400020
  • scopus:77953287872
ISSN
1873-734X
1010-7940
DOI
10.1016/j.ejcts.2010.01.028
language
English
LU publication?
yes
id
ad0d7a85-9299-4c8d-bb46-d6bb6cdd4d23 (old id 1657492)
date added to LUP
2010-08-31 09:59:51
date last changed
2018-05-29 12:27:40
@inproceedings{ad0d7a85-9299-4c8d-bb46-d6bb6cdd4d23,
  abstract     = {Objective: Negative pressure wound therapy (NPWT) is a recently introduced treatment modality for post-sternotomy mediastinitis. The aim of this study was to compare the mortality rate, the sternal re-infection rate and the length of hospital stay in patients with post-sternotomy mediastinitis after NPWT and conventional treatment. Methods: We retrospectively analysed 118 patients with post-sternotomy mediastinitis after cardiac surgery. One group of 69 patients was treated with NPWT and the other group of 49 patients with conventional therapy. Results: There were no major differences between the two groups concerning preoperative data (EuroScore) or primary cardiac surgery (mainly coronary artery bypass grafting). NPWT therapy was found to reduce mortality rate (P = 0.005) and sternal re-infection rate (P = 0.008) compared with conventional treatment and tended to lead to a shorter length of hospital stay (P = 0.08). Conclusions: NPWT for post-sternotomy mediastinitis demonstrates encouraging clinical results with a reduction of the mortality rate and the sternal re-infection rate compared with conventional treatment. The results support NPWT as the first-line treatment for deep sternal wound infections. (C) 2010 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.},
  author       = {Petzina, Rainer and Hoffmann, Julia and Navasardyan, Artashes and Malmsjö, Malin and Stamm, Christof and Unbehaun, Axel and Hetzer, Roland},
  booktitle    = {European Journal of Cardio-Thoracic Surgery},
  issn         = {1873-734X},
  keyword      = {Wound healing,Mediastinal infection,Cardiac surgery},
  language     = {eng},
  number       = {1},
  pages        = {110--113},
  publisher    = {Elsevier},
  title        = {Negative pressure wound therapy for post-sternotomy mediastinitis reduces mortality rate and sternal re-infection rate compared to conventional treatment},
  url          = {http://dx.doi.org/10.1016/j.ejcts.2010.01.028},
  volume       = {38},
  year         = {2010},
}