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Management of premature prelabor rupture of the membranes.

Strevens, Helena LU ; Allen, Kirsten and Thornton, Jim G (2010) In Annals of the New York Academy of Sciences 1205(1). p.123-129
Abstract
Premature prelabor rupture of the fetal membranes affects about 3% of pregnancies. The cause is usually infection, especially at earlier gestations. The prognosis and the risks of delivery are both much worse at earlier gestations. Before viable pregnancy, termination may be offered. Once the fetus is viable, steroids to mature the fetal lungs and antibiotics to reduce infection are the mainstays of treatment. Delivery is recommended in the presence of signs of clear-cut infection at early gestational ages. At later ones, balancing the risks of infection from conservative treatment against the risk of prematurity from delivery is difficult. Published trials to date have not given clear guidance, but a number are ongoing.
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Premature Rupture: epidemiology, Fetal Membranes, Premature Rupture: etiology, Premature Rupture: prevention & control, Premature Rupture: therapy
in
Annals of the New York Academy of Sciences
volume
1205
issue
1
pages
123 - 129
publisher
John Wiley & Sons Inc.
external identifiers
  • wos:000283095800019
  • pmid:20840263
  • scopus:77957057484
  • pmid:20840263
ISSN
0077-8923
DOI
10.1111/j.1749-6632.2010.05654.x
language
English
LU publication?
yes
id
a549bda2-bd00-43fb-b345-d2c8735a7fc6 (old id 1688268)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/20840263?dopt=Abstract
date added to LUP
2016-04-04 09:32:53
date last changed
2025-01-06 09:44:06
@article{a549bda2-bd00-43fb-b345-d2c8735a7fc6,
  abstract     = {{Premature prelabor rupture of the fetal membranes affects about 3% of pregnancies. The cause is usually infection, especially at earlier gestations. The prognosis and the risks of delivery are both much worse at earlier gestations. Before viable pregnancy, termination may be offered. Once the fetus is viable, steroids to mature the fetal lungs and antibiotics to reduce infection are the mainstays of treatment. Delivery is recommended in the presence of signs of clear-cut infection at early gestational ages. At later ones, balancing the risks of infection from conservative treatment against the risk of prematurity from delivery is difficult. Published trials to date have not given clear guidance, but a number are ongoing.}},
  author       = {{Strevens, Helena and Allen, Kirsten and Thornton, Jim G}},
  issn         = {{0077-8923}},
  keywords     = {{Premature Rupture: epidemiology; Fetal Membranes; Premature Rupture: etiology; Premature Rupture: prevention & control; Premature Rupture: therapy}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{123--129}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Annals of the New York Academy of Sciences}},
  title        = {{Management of premature prelabor rupture of the membranes.}},
  url          = {{http://dx.doi.org/10.1111/j.1749-6632.2010.05654.x}},
  doi          = {{10.1111/j.1749-6632.2010.05654.x}},
  volume       = {{1205}},
  year         = {{2010}},
}