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Plasma levels of apolipoprotein M in normal and complicated pregnancy.

Ahnström, Josefin LU ; Lindqvist, Pelle LU ; Walle, Ursula and Dahlbäck, Björn LU (2010) In Acta Obstetricia et Gynecologica Scandinavica 89(9). p.1214-1217
Abstract
Apolipoprotein M (apoM) is mainly associated with high-density lipoprotein in human plasma. Despite several studies suggesting apoM as an anti-atherogenic, its function is not yet fully understood. Plasma apoM was measured in normal pregnancies at four different gestational ages and in the postpartum period to investigate whether the concentration of apoM changes during pregnancy. In addition, apoM was measured at 13 weeks in women who subsequently developed preeclampsia, gestational diabetes, recurrent miscarriage, or small-for-gestational age babies, and in women with uncomplicated pregnancies. The plasma concentrations of apoM increased during pregnancy to reach highest levels in the postpartum period. Thus, plasma apoM in non-pregnant... (More)
Apolipoprotein M (apoM) is mainly associated with high-density lipoprotein in human plasma. Despite several studies suggesting apoM as an anti-atherogenic, its function is not yet fully understood. Plasma apoM was measured in normal pregnancies at four different gestational ages and in the postpartum period to investigate whether the concentration of apoM changes during pregnancy. In addition, apoM was measured at 13 weeks in women who subsequently developed preeclampsia, gestational diabetes, recurrent miscarriage, or small-for-gestational age babies, and in women with uncomplicated pregnancies. The plasma concentrations of apoM increased during pregnancy to reach highest levels in the postpartum period. Thus, plasma apoM in non-pregnant women was around 0.77 micromol/l, 0.88 micromol/l at 40 gestational weeks, and 1.05 micromol/l in the postpartum period (p < 0.0001). No differences in plasma concentrations of apoM were found among the studied pregnancy complications. (Less)
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organization
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type
Contribution to journal
publication status
published
subject
keywords
Pregnancy Complications: blood, Pregnancy: blood, Apolipoproteins: blood, Postpartum Period: blood
in
Acta Obstetricia et Gynecologica Scandinavica
volume
89
issue
9
pages
1214 - 1217
publisher
Wiley-Blackwell
external identifiers
  • WOS:000282897700018
  • PMID:20804348
  • Scopus:77956334287
ISSN
1600-0412
DOI
10.3109/00016349.2010.486434
language
English
LU publication?
yes
id
f820533d-1a5a-4275-9700-e3c8afb17c70 (old id 1688729)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/20804348?dopt=Abstract
date added to LUP
2010-10-03 19:29:21
date last changed
2017-01-01 07:49:50
@article{f820533d-1a5a-4275-9700-e3c8afb17c70,
  abstract     = {Apolipoprotein M (apoM) is mainly associated with high-density lipoprotein in human plasma. Despite several studies suggesting apoM as an anti-atherogenic, its function is not yet fully understood. Plasma apoM was measured in normal pregnancies at four different gestational ages and in the postpartum period to investigate whether the concentration of apoM changes during pregnancy. In addition, apoM was measured at 13 weeks in women who subsequently developed preeclampsia, gestational diabetes, recurrent miscarriage, or small-for-gestational age babies, and in women with uncomplicated pregnancies. The plasma concentrations of apoM increased during pregnancy to reach highest levels in the postpartum period. Thus, plasma apoM in non-pregnant women was around 0.77 micromol/l, 0.88 micromol/l at 40 gestational weeks, and 1.05 micromol/l in the postpartum period (p &lt; 0.0001). No differences in plasma concentrations of apoM were found among the studied pregnancy complications.},
  author       = {Ahnström, Josefin and Lindqvist, Pelle and Walle, Ursula and Dahlbäck, Björn},
  issn         = {1600-0412},
  keyword      = {Pregnancy Complications: blood,Pregnancy: blood,Apolipoproteins: blood,Postpartum Period: blood},
  language     = {eng},
  number       = {9},
  pages        = {1214--1217},
  publisher    = {Wiley-Blackwell},
  series       = {Acta Obstetricia et Gynecologica Scandinavica},
  title        = {Plasma levels of apolipoprotein M in normal and complicated pregnancy.},
  url          = {http://dx.doi.org/10.3109/00016349.2010.486434},
  volume       = {89},
  year         = {2010},
}