Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Common and diverging integrin signals downstream of adhesion and mechanical stimuli and their interplay with reactive oxygen species

Zeller, Kathrin Stephanie LU orcid and Johansson, Staffan LU (2014) In Biophysical Reviews and Letters 9(2). p.159-171
Abstract

The integrin family of adhesion receptors regulates basic functions of cells, and the signals they induce are altered in tumor cells. In this review we discuss how different integrin-dependent signals are generated during cell adhesion and by physical forces acting on cells. We also describe how reactive oxygen species are integral parts of integrin signaling and highlight a few important questions in the field. Answers to those may improve our understanding of integrins and their role in the development of cancer.

Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
adhesion, Integrin, mechano-stimuli, reactive oxygen species, signaling
in
Biophysical Reviews and Letters
volume
9
issue
2
pages
13 pages
publisher
World Scientific Publishing
external identifiers
  • scopus:84903385872
ISSN
1793-0480
DOI
10.1142/S1793048014300011
language
English
LU publication?
yes
id
17077502-80ed-4a51-bf0b-f2cf0e9b0448
date added to LUP
2021-02-02 15:50:31
date last changed
2022-02-01 20:00:07
@article{17077502-80ed-4a51-bf0b-f2cf0e9b0448,
  abstract     = {{<p>The integrin family of adhesion receptors regulates basic functions of cells, and the signals they induce are altered in tumor cells. In this review we discuss how different integrin-dependent signals are generated during cell adhesion and by physical forces acting on cells. We also describe how reactive oxygen species are integral parts of integrin signaling and highlight a few important questions in the field. Answers to those may improve our understanding of integrins and their role in the development of cancer.</p>}},
  author       = {{Zeller, Kathrin Stephanie and Johansson, Staffan}},
  issn         = {{1793-0480}},
  keywords     = {{adhesion; Integrin; mechano-stimuli; reactive oxygen species; signaling}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{159--171}},
  publisher    = {{World Scientific Publishing}},
  series       = {{Biophysical Reviews and Letters}},
  title        = {{Common and diverging integrin signals downstream of adhesion and mechanical stimuli and their interplay with reactive oxygen species}},
  url          = {{http://dx.doi.org/10.1142/S1793048014300011}},
  doi          = {{10.1142/S1793048014300011}},
  volume       = {{9}},
  year         = {{2014}},
}