Alignment between PIN1 Polarity and Microtubule Orientation in the Shoot Apical Meristem Reveals a Tight Coupling between Morphogenesis and Auxin Transport
(2010) In PLoS Biology 8(10).- Abstract
- Morphogenesis during multicellular development is regulated by intercellular signaling molecules as well as by the mechanical properties of individual cells. In particular, normal patterns of organogenesis in plants require coordination between growth direction and growth magnitude. How this is achieved remains unclear. Here we show that in Arabidopsis thaliana, auxin patterning and cellular growth are linked through a correlated pattern of auxin efflux carrier localization and cortical microtubule orientation. Our experiments reveal that both PIN1 localization and microtubule array orientation are likely to respond to a shared upstream regulator that appears to be biomechanical in nature. Lastly, through mathematical modeling we show that... (More)
- Morphogenesis during multicellular development is regulated by intercellular signaling molecules as well as by the mechanical properties of individual cells. In particular, normal patterns of organogenesis in plants require coordination between growth direction and growth magnitude. How this is achieved remains unclear. Here we show that in Arabidopsis thaliana, auxin patterning and cellular growth are linked through a correlated pattern of auxin efflux carrier localization and cortical microtubule orientation. Our experiments reveal that both PIN1 localization and microtubule array orientation are likely to respond to a shared upstream regulator that appears to be biomechanical in nature. Lastly, through mathematical modeling we show that such a biophysical coupling could mediate the feedback loop between auxin and its transport that underlies plant phyllotaxis. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1720247
- author
- Heisler, Marcus G. ; Hamant, Olivier ; Krupinski, Pawel LU ; Uyttewaal, Magalie ; Ohno, Carolyn ; Jönsson, Henrik LU ; Traas, Jan and Meyerowitz, Elliot M.
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- PLoS Biology
- volume
- 8
- issue
- 10
- publisher
- Public Library of Science (PLoS)
- external identifiers
-
- wos:000283495100015
- scopus:78149401660
- pmid:20976043
- ISSN
- 1545-7885
- DOI
- 10.1371/journal.pbio.1000516
- language
- English
- LU publication?
- yes
- id
- b5fab2a1-7f7d-4a80-88b1-5f6740ac519c (old id 1720247)
- date added to LUP
- 2016-04-01 15:02:05
- date last changed
- 2024-04-11 04:20:07
@article{b5fab2a1-7f7d-4a80-88b1-5f6740ac519c, abstract = {{Morphogenesis during multicellular development is regulated by intercellular signaling molecules as well as by the mechanical properties of individual cells. In particular, normal patterns of organogenesis in plants require coordination between growth direction and growth magnitude. How this is achieved remains unclear. Here we show that in Arabidopsis thaliana, auxin patterning and cellular growth are linked through a correlated pattern of auxin efflux carrier localization and cortical microtubule orientation. Our experiments reveal that both PIN1 localization and microtubule array orientation are likely to respond to a shared upstream regulator that appears to be biomechanical in nature. Lastly, through mathematical modeling we show that such a biophysical coupling could mediate the feedback loop between auxin and its transport that underlies plant phyllotaxis.}}, author = {{Heisler, Marcus G. and Hamant, Olivier and Krupinski, Pawel and Uyttewaal, Magalie and Ohno, Carolyn and Jönsson, Henrik and Traas, Jan and Meyerowitz, Elliot M.}}, issn = {{1545-7885}}, language = {{eng}}, number = {{10}}, publisher = {{Public Library of Science (PLoS)}}, series = {{PLoS Biology}}, title = {{Alignment between PIN1 Polarity and Microtubule Orientation in the Shoot Apical Meristem Reveals a Tight Coupling between Morphogenesis and Auxin Transport}}, url = {{http://dx.doi.org/10.1371/journal.pbio.1000516}}, doi = {{10.1371/journal.pbio.1000516}}, volume = {{8}}, year = {{2010}}, }