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Opioid dispensing in relation to arthroscopic knee surgery in Denmark from 2006 to 2018

Thorlund, Jonas Bloch ; Lundberg, Matilde ; Petersen, Jindong Ding ; Englund, Martin LU orcid ; Viberg, Bjarke ; Waldorff, Frans Boch and Søndergaard, Jens (2023) In Danish Medical Journal 70(9).
Abstract

INTRODUCTION. In the US, opioids are commonly prescribed after arthroscopic knee surgery. We aimed to investigate opioid dispensing in relation to arthroscopic knee surgeries from 2006 to 2018 in Denmark. METHODS. In Danish registries, we identified patients (≥ 15 years old) having arthroscopic knee surgery (anterior cruciate ligament (ACL) reconstruction; meniscal surgery; cartilage resection; synovectomy and diagnostic arthroscopy) between 1 January 2006 and 31 December 2018 and opioid dispensing (oral morphine equivalents (OMEQ)) within seven days after discharge from surgery. RESULTS. Among 218,940 patients, 15,263 (7%) had an opioid dispensed within seven days after being discharged following surgery. The opioid dispensing... (More)

INTRODUCTION. In the US, opioids are commonly prescribed after arthroscopic knee surgery. We aimed to investigate opioid dispensing in relation to arthroscopic knee surgeries from 2006 to 2018 in Denmark. METHODS. In Danish registries, we identified patients (≥ 15 years old) having arthroscopic knee surgery (anterior cruciate ligament (ACL) reconstruction; meniscal surgery; cartilage resection; synovectomy and diagnostic arthroscopy) between 1 January 2006 and 31 December 2018 and opioid dispensing (oral morphine equivalents (OMEQ)) within seven days after discharge from surgery. RESULTS. Among 218,940 patients, 15,263 (7%) had an opioid dispensed within seven days after being discharged following surgery. The opioid dispensing incidence (per 1,000 persons/year) increased during the study period for all procedures. This trend was more pronounced for ACL reconstruction, which recorded an increase from 86 (95% confidence interval (CI): 75-99) in 2006 to 278 (95% CI: 255-301) in 2018, corresponding to 9% and 28% of ACL patients, respectively. In the same period, the average amount of opioids dispensed within the first seven days after discharge decreased (change: 70.0 OMEQ (95% CI: 12.4-127.5)). Tramadol and oxycodone were the most commonly dispensed opioids. CONCLUSION. About 7% of patients had an opioid dispensed within the first seven days after discharge following arthroscopic knee surgery. The incidence of opioids dispensed increased for all investigated procedures from 2006 to 2018. In the same period, the average amount of opioids dispensed within the first seven days after discharge decreased.

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; ; ; ; ; and
organization
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type
Contribution to journal
publication status
published
subject
in
Danish Medical Journal
volume
70
issue
9
article number
A01230032
publisher
Danish Medical Association
external identifiers
  • pmid:37622647
  • scopus:85168719652
ISSN
0011-6092
language
English
LU publication?
yes
id
173dd52b-844c-4e56-b76b-be501e6c5f10
alternative location
https://ugeskriftet.dk/dmj/opioid-dispensing-relation-arthroscopic-knee-surgery-denmark-2006-2018
date added to LUP
2023-11-28 14:00:26
date last changed
2024-04-25 16:47:23
@article{173dd52b-844c-4e56-b76b-be501e6c5f10,
  abstract     = {{<p>INTRODUCTION. In the US, opioids are commonly prescribed after arthroscopic knee surgery. We aimed to investigate opioid dispensing in relation to arthroscopic knee surgeries from 2006 to 2018 in Denmark. METHODS. In Danish registries, we identified patients (≥ 15 years old) having arthroscopic knee surgery (anterior cruciate ligament (ACL) reconstruction; meniscal surgery; cartilage resection; synovectomy and diagnostic arthroscopy) between 1 January 2006 and 31 December 2018 and opioid dispensing (oral morphine equivalents (OMEQ)) within seven days after discharge from surgery. RESULTS. Among 218,940 patients, 15,263 (7%) had an opioid dispensed within seven days after being discharged following surgery. The opioid dispensing incidence (per 1,000 persons/year) increased during the study period for all procedures. This trend was more pronounced for ACL reconstruction, which recorded an increase from 86 (95% confidence interval (CI): 75-99) in 2006 to 278 (95% CI: 255-301) in 2018, corresponding to 9% and 28% of ACL patients, respectively. In the same period, the average amount of opioids dispensed within the first seven days after discharge decreased (change: 70.0 OMEQ (95% CI: 12.4-127.5)). Tramadol and oxycodone were the most commonly dispensed opioids. CONCLUSION. About 7% of patients had an opioid dispensed within the first seven days after discharge following arthroscopic knee surgery. The incidence of opioids dispensed increased for all investigated procedures from 2006 to 2018. In the same period, the average amount of opioids dispensed within the first seven days after discharge decreased.</p>}},
  author       = {{Thorlund, Jonas Bloch and Lundberg, Matilde and Petersen, Jindong Ding and Englund, Martin and Viberg, Bjarke and Waldorff, Frans Boch and Søndergaard, Jens}},
  issn         = {{0011-6092}},
  language     = {{eng}},
  number       = {{9}},
  publisher    = {{Danish Medical Association}},
  series       = {{Danish Medical Journal}},
  title        = {{Opioid dispensing in relation to arthroscopic knee surgery in Denmark from 2006 to 2018}},
  url          = {{https://ugeskriftet.dk/dmj/opioid-dispensing-relation-arthroscopic-knee-surgery-denmark-2006-2018}},
  volume       = {{70}},
  year         = {{2023}},
}