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Magnetic Resonance Findings in the Pregeniculate Visual Pathways in Leber Hereditary Optic Neuropathy.

van Westen, Danielle LU ; Hammar, Björn LU and Bynke, Gunnel (2011) In Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 31. p.48-51
Abstract
Two relatives, a 61-year-old man and the 21-year-old grandson of his sister, suffered from bilateral visual loss and were diagnosed with Leber hereditary optic neuropathy. In both cases, the diagnosis was molecularly confirmed with the 11778 mitochondrial mutation. MRI showed increased T2 signal not only in the optic nerves and chiasm but also in the optic tracts, extending to the lateral geniculate bodies. To our knowledge, the latter finding has not been described previously.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
volume
31
pages
48 - 51
external identifiers
  • wos:000287238700012
  • pmid:21157374
  • scopus:79952134073
ISSN
1536-5166
DOI
10.1097/WNO.0b013e3181f3f203
language
English
LU publication?
yes
id
1e6607b8-43e1-45e4-bfb7-1bd497e3b7b3 (old id 1756394)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21157374?dopt=Abstract
date added to LUP
2011-01-03 15:39:18
date last changed
2017-02-26 04:25:30
@article{1e6607b8-43e1-45e4-bfb7-1bd497e3b7b3,
  abstract     = {Two relatives, a 61-year-old man and the 21-year-old grandson of his sister, suffered from bilateral visual loss and were diagnosed with Leber hereditary optic neuropathy. In both cases, the diagnosis was molecularly confirmed with the 11778 mitochondrial mutation. MRI showed increased T2 signal not only in the optic nerves and chiasm but also in the optic tracts, extending to the lateral geniculate bodies. To our knowledge, the latter finding has not been described previously.},
  author       = {van Westen, Danielle and Hammar, Björn and Bynke, Gunnel},
  issn         = {1536-5166},
  language     = {eng},
  pages        = {48--51},
  series       = {Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society},
  title        = {Magnetic Resonance Findings in the Pregeniculate Visual Pathways in Leber Hereditary Optic Neuropathy.},
  url          = {http://dx.doi.org/10.1097/WNO.0b013e3181f3f203},
  volume       = {31},
  year         = {2011},
}