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Relation between pain and skeletal metastasis in patients with prostate or breast cancer.

Levren, Gabriella; Sadik, May; Gjertsson, Peter; Lomsky, Milan; Michanek, Annika and Edenbrandt, Lars LU (2011) In Clinical Physiology and Functional Imaging 31. p.193-195
Abstract
The aim of this study was to examine the relation between pain and bone metastases in a group of patients with prostate or breast cancer that had been referred for bone scintigraphy. Whole-body bone scans, anterior and posterior views obtained with a dual detector gamma camera were studied from 101 consecutive patients who had undergone scintigraphy (600 MBq Tc-99m MDP) because of suspected bone metastatic disease. At the time of the examination, all patients were asked whether they felt any pain or had recently a trauma. This information was correlated with the classifications regarding the presence or absence of bone metastases made by a group of three experienced physicians. In patients with prostate cancer, we found metastases in 47%... (More)
The aim of this study was to examine the relation between pain and bone metastases in a group of patients with prostate or breast cancer that had been referred for bone scintigraphy. Whole-body bone scans, anterior and posterior views obtained with a dual detector gamma camera were studied from 101 consecutive patients who had undergone scintigraphy (600 MBq Tc-99m MDP) because of suspected bone metastatic disease. At the time of the examination, all patients were asked whether they felt any pain or had recently a trauma. This information was correlated with the classifications regarding the presence or absence of bone metastases made by a group of three experienced physicians. In patients with prostate cancer, we found metastases in 47% (18/38) of the patients with pain, but only in 12% (2/17) of the patients without pain (p = 0·01). In patients with breast cancer, on the other hand, metastases were more common in patients without pain (71%; 10/14) than in patients with pain (34%; 11/32) (p = 0·02). In conclusion, a significant relation between pain and skeletal metastases could be found in patients with prostate cancer and a reverse relation in patients with breast cancer. (Less)
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organization
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type
Contribution to journal
publication status
published
subject
in
Clinical Physiology and Functional Imaging
volume
31
pages
193 - 195
publisher
Wiley Online Library
external identifiers
  • wos:000289258100005
  • pmid:21114613
  • scopus:79953760944
ISSN
1475-0961
DOI
10.1111/j.1475-097X.2010.00999.x
language
English
LU publication?
yes
id
92f77764-fd33-4c9c-8439-b71339727715 (old id 1757013)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21114613?dopt=Abstract
date added to LUP
2011-01-03 11:24:08
date last changed
2017-01-08 05:21:38
@article{92f77764-fd33-4c9c-8439-b71339727715,
  abstract     = {The aim of this study was to examine the relation between pain and bone metastases in a group of patients with prostate or breast cancer that had been referred for bone scintigraphy. Whole-body bone scans, anterior and posterior views obtained with a dual detector gamma camera were studied from 101 consecutive patients who had undergone scintigraphy (600 MBq Tc-99m MDP) because of suspected bone metastatic disease. At the time of the examination, all patients were asked whether they felt any pain or had recently a trauma. This information was correlated with the classifications regarding the presence or absence of bone metastases made by a group of three experienced physicians. In patients with prostate cancer, we found metastases in 47% (18/38) of the patients with pain, but only in 12% (2/17) of the patients without pain (p = 0·01). In patients with breast cancer, on the other hand, metastases were more common in patients without pain (71%; 10/14) than in patients with pain (34%; 11/32) (p = 0·02). In conclusion, a significant relation between pain and skeletal metastases could be found in patients with prostate cancer and a reverse relation in patients with breast cancer.},
  author       = {Levren, Gabriella and Sadik, May and Gjertsson, Peter and Lomsky, Milan and Michanek, Annika and Edenbrandt, Lars},
  issn         = {1475-0961},
  language     = {eng},
  pages        = {193--195},
  publisher    = {Wiley Online Library},
  series       = {Clinical Physiology and Functional Imaging},
  title        = {Relation between pain and skeletal metastasis in patients with prostate or breast cancer.},
  url          = {http://dx.doi.org/10.1111/j.1475-097X.2010.00999.x},
  volume       = {31},
  year         = {2011},
}