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Spatial, individual and temporal variation of the high frequency QRS amplitudes in the 12 standard electrocardiographic leads

Pettersson, Jonas LU ; Carro, E. ; Edenbrandt, Lars LU ; Pahlm, Olle LU ; Ringborn, Michael LU ; Sörnmo, Leif LU ; Warren, S. and Wagner, G. (2000) In American Heart Journal 139(2, part 1). p.352-358
Abstract
BACKGROUND: Analysis of high-frequency QRS amplitudes (HF-QRS) may provide an additional diagnostic tool in patients with heart disease, but the basic properties of these waveforms have not been sufficiently investigated. This study describes the spatial, individual, and temporal variation at rest of HF-QRS recorded with the 12 standard electrocardiographic leads in patients with ischemic heart disease.



METHODS AND RESULTS: Two consecutive electrocardiographic recordings from 67 patients were signal averaged and analyzed within a bandwidth of 150 to 250 Hz. The HF-QRS values were expressed as root mean square values. There was a spatial variation in HF-QRS among the 12 leads, with higher amplitudes in V(2) through V(4),... (More)
BACKGROUND: Analysis of high-frequency QRS amplitudes (HF-QRS) may provide an additional diagnostic tool in patients with heart disease, but the basic properties of these waveforms have not been sufficiently investigated. This study describes the spatial, individual, and temporal variation at rest of HF-QRS recorded with the 12 standard electrocardiographic leads in patients with ischemic heart disease.



METHODS AND RESULTS: Two consecutive electrocardiographic recordings from 67 patients were signal averaged and analyzed within a bandwidth of 150 to 250 Hz. The HF-QRS values were expressed as root mean square values. There was a spatial variation in HF-QRS among the 12 leads, with higher amplitudes in V(2) through V(4), II, aVF, and III. The individual variation among the patients was large for all leads. The sum of the HF-QRS for all 12 leads in each patient ranged from 20 to 75 microV (mean 36 +/- 11 microV). The mean of the temporal variation in HF-QRS for all 12 leads between the 2 recordings was only 0.10 +/- 0. 09 microV.



CONCLUSIONS: Because of the large individual variation, analysis of HF-QRS is probably most applicable in monitoring situations when it is possible to track changes in a patient over time. The temporal variation in HF-QRS at rest is small, both in patients with and those without prior myocardial infarction. (Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
American Heart Journal
volume
139
issue
2, part 1
pages
352 - 358
publisher
Mosby-Elsevier
external identifiers
  • scopus:0033983461
ISSN
1097-6744
DOI
10.1016/S0002-8703(00)90246-1
language
English
LU publication?
yes
id
c55dbf1a-7792-488b-a38e-563374ef4f80 (old id 1758701)
date added to LUP
2016-04-04 07:37:51
date last changed
2022-02-20 20:40:46
@article{c55dbf1a-7792-488b-a38e-563374ef4f80,
  abstract     = {{BACKGROUND: Analysis of high-frequency QRS amplitudes (HF-QRS) may provide an additional diagnostic tool in patients with heart disease, but the basic properties of these waveforms have not been sufficiently investigated. This study describes the spatial, individual, and temporal variation at rest of HF-QRS recorded with the 12 standard electrocardiographic leads in patients with ischemic heart disease.<br/><br>
<br/><br>
METHODS AND RESULTS: Two consecutive electrocardiographic recordings from 67 patients were signal averaged and analyzed within a bandwidth of 150 to 250 Hz. The HF-QRS values were expressed as root mean square values. There was a spatial variation in HF-QRS among the 12 leads, with higher amplitudes in V(2) through V(4), II, aVF, and III. The individual variation among the patients was large for all leads. The sum of the HF-QRS for all 12 leads in each patient ranged from 20 to 75 microV (mean 36 +/- 11 microV). The mean of the temporal variation in HF-QRS for all 12 leads between the 2 recordings was only 0.10 +/- 0. 09 microV.<br/><br>
<br/><br>
CONCLUSIONS: Because of the large individual variation, analysis of HF-QRS is probably most applicable in monitoring situations when it is possible to track changes in a patient over time. The temporal variation in HF-QRS at rest is small, both in patients with and those without prior myocardial infarction.}},
  author       = {{Pettersson, Jonas and Carro, E. and Edenbrandt, Lars and Pahlm, Olle and Ringborn, Michael and Sörnmo, Leif and Warren, S. and Wagner, G.}},
  issn         = {{1097-6744}},
  language     = {{eng}},
  number       = {{2, part 1}},
  pages        = {{352--358}},
  publisher    = {{Mosby-Elsevier}},
  series       = {{American Heart Journal}},
  title        = {{Spatial, individual and temporal variation of the high frequency QRS amplitudes in the 12 standard electrocardiographic leads}},
  url          = {{http://dx.doi.org/10.1016/S0002-8703(00)90246-1}},
  doi          = {{10.1016/S0002-8703(00)90246-1}},
  volume       = {{139}},
  year         = {{2000}},
}