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Changes in high-frequency QRS components are more sensitive than ST segment deviation for detecting acute coronary artery occlusion

Pettersson, Jonas LU ; Carro, E.; Edenbrandt, Lars LU ; Ringborn, Michael LU ; Sörnmo, Leif LU ; Warren, Stafford G. and Wagner, Galen S. (2000) In Journal of the American College of Cardiology 36(6). p.1827-1834
Abstract
OBJECTIVES



This study describes changes in high-frequency QRS components (HF-QRS) during percutaneous transluminal coronary angioplasty (PTCA) and compares the ability of these changes in HF-QRS and ST-segment deviation in the standard 12-lead electrocardiogram (ECG) to detect acute coronary artery occlusion.



BACKGROUND



Previous studies have shown decreased HF-QRS in the frequency range of 150–250 Hz during acute myocardial ischemia. It would be important to know whether the high-frequency analysis could add information to that available from the ST segments in the standard ECG.



METHODS



The study population consisted of 52 patients undergoing... (More)
OBJECTIVES



This study describes changes in high-frequency QRS components (HF-QRS) during percutaneous transluminal coronary angioplasty (PTCA) and compares the ability of these changes in HF-QRS and ST-segment deviation in the standard 12-lead electrocardiogram (ECG) to detect acute coronary artery occlusion.



BACKGROUND



Previous studies have shown decreased HF-QRS in the frequency range of 150–250 Hz during acute myocardial ischemia. It would be important to know whether the high-frequency analysis could add information to that available from the ST segments in the standard ECG.



METHODS



The study population consisted of 52 patients undergoing prolonged balloon occlusion during PTCA. Signal-averaged electrocardiograms (SAECG) were recorded prior to and during the balloon inflation. The HF-QRS were determined within a bandwidth of 150–250 Hz in the preinflation and inflation SAECGs. The ST-segment deviation during inflation was determined in the standard frequency range.



RESULTS



The sensitivity for detecting acute coronary artery occlusion was 88% using the high-frequency method. In 71% of the patients there was ST elevation during inflation. If both ST elevation and depression were considered, the sensitivity was 79%. The sensitivity was significantly higher using the high-frequency method, p < 0.002, compared with the assessment of ST elevation.



CONCLUSIONS



Acute coronary artery occlusion is detected with higher sensitivity using high-frequency QRS analysis compared with conventional assessment of ST segments. This result suggests that analysis of HF-QRS could provide an adjunctive tool with high sensitivity for detecting acute myocardial ischemia. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of the American College of Cardiology
volume
36
issue
6
pages
1827 - 1834
publisher
Elsevier USA
external identifiers
  • scopus:0034669446
ISSN
0735-1097
DOI
10.1016/S0735-1097(00)00936-0
language
English
LU publication?
yes
id
8d40cf1d-de79-44d9-a347-d1dbd2e9a714 (old id 1758850)
date added to LUP
2011-01-04 13:01:32
date last changed
2017-08-20 04:36:56
@article{8d40cf1d-de79-44d9-a347-d1dbd2e9a714,
  abstract     = {OBJECTIVES<br/><br>
<br/><br>
This study describes changes in high-frequency QRS components (HF-QRS) during percutaneous transluminal coronary angioplasty (PTCA) and compares the ability of these changes in HF-QRS and ST-segment deviation in the standard 12-lead electrocardiogram (ECG) to detect acute coronary artery occlusion.<br/><br>
<br/><br>
BACKGROUND<br/><br>
<br/><br>
Previous studies have shown decreased HF-QRS in the frequency range of 150–250 Hz during acute myocardial ischemia. It would be important to know whether the high-frequency analysis could add information to that available from the ST segments in the standard ECG.<br/><br>
<br/><br>
METHODS<br/><br>
<br/><br>
The study population consisted of 52 patients undergoing prolonged balloon occlusion during PTCA. Signal-averaged electrocardiograms (SAECG) were recorded prior to and during the balloon inflation. The HF-QRS were determined within a bandwidth of 150–250 Hz in the preinflation and inflation SAECGs. The ST-segment deviation during inflation was determined in the standard frequency range.<br/><br>
<br/><br>
RESULTS<br/><br>
<br/><br>
The sensitivity for detecting acute coronary artery occlusion was 88% using the high-frequency method. In 71% of the patients there was ST elevation during inflation. If both ST elevation and depression were considered, the sensitivity was 79%. The sensitivity was significantly higher using the high-frequency method, p &lt; 0.002, compared with the assessment of ST elevation.<br/><br>
<br/><br>
CONCLUSIONS<br/><br>
<br/><br>
Acute coronary artery occlusion is detected with higher sensitivity using high-frequency QRS analysis compared with conventional assessment of ST segments. This result suggests that analysis of HF-QRS could provide an adjunctive tool with high sensitivity for detecting acute myocardial ischemia.},
  author       = {Pettersson, Jonas and Carro, E. and Edenbrandt, Lars and Ringborn, Michael and Sörnmo, Leif and Warren, Stafford G. and Wagner, Galen S.},
  issn         = {0735-1097},
  language     = {eng},
  number       = {6},
  pages        = {1827--1834},
  publisher    = {Elsevier USA},
  series       = {Journal of the American College of Cardiology},
  title        = {Changes in high-frequency QRS components are more sensitive than ST segment deviation for detecting acute coronary artery occlusion},
  url          = {http://dx.doi.org/10.1016/S0735-1097(00)00936-0},
  volume       = {36},
  year         = {2000},
}