Is early migration enough to explain late clinical loosening of hip prostheses?
Mjöberg, Bengt LU
(2020)
In EFORT Open Reviews
5(2).
p.113-117
- Abstract
Prosthetic loosening has been debated for decades, both in terms of the timing and nature of the triggering events. Multiple radiostereometric studies of hip prostheses have now shown that early migration poses a risk of future clinical failure, but is this enough to explain late clinical loosening? To answer this question, the progression of loosening from initiation to radiographic detection is described; and the need for explanations other than early prosthetic loosening is analysed, such as stress-shielding, particle disease, and metal sensitivity. Much evidence indicates that prosthetic loosening has already been initiated during or shortly after the surgery, and that the subsequent progression of loosening is affected by... (More)
Prosthetic loosening has been debated for decades, both in terms of the timing and nature of the triggering events. Multiple radiostereometric studies of hip prostheses have now shown that early migration poses a risk of future clinical failure, but is this enough to explain late clinical loosening? To answer this question, the progression of loosening from initiation to radiographic detection is described; and the need for explanations other than early prosthetic loosening is analysed, such as stress-shielding, particle disease, and metal sensitivity. Much evidence indicates that prosthetic loosening has already been initiated during or shortly after the surgery, and that the subsequent progression of loosening is affected by biomechanical factors, fluid pressure fluctuations and inflammatory responses to necrotic cells and cell fragments, i.e. the concept of late loosening appears to be a misinterpretation of late-detected loosening. Clinical implications: atraumatic surgery and initial prosthetic stability are crucial in ensuring low risk of prosthetic loosening.
(Less)
- author
- Mjöberg, Bengt
LU
- organization
- publishing date
- 2020-02-03
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Periprosthetic osteolysis, Prosthetic loosening, Radiostereometric analysis
- in
- EFORT Open Reviews
- volume
- 5
- issue
- 2
- pages
- 5 pages
- publisher
- British Editorial Society of Bone & Joint Surgery
- external identifiers
-
- pmid:32175098
- scopus:85080918584
- ISSN
- 2396-7544
- DOI
- 10.1302/2058-5241.5.190014
- language
- English
- LU publication?
- yes
- id
- 17ea6f4d-21c2-4aac-aa08-d997d87805b6
- date added to LUP
- 2020-03-18 16:42:11
- date last changed
- 2025-01-10 08:32:42
@article{17ea6f4d-21c2-4aac-aa08-d997d87805b6,
abstract = {{<p>Prosthetic loosening has been debated for decades, both in terms of the timing and nature of the triggering events. Multiple radiostereometric studies of hip prostheses have now shown that early migration poses a risk of future clinical failure, but is this enough to explain late clinical loosening? To answer this question, the progression of loosening from initiation to radiographic detection is described; and the need for explanations other than early prosthetic loosening is analysed, such as stress-shielding, particle disease, and metal sensitivity. Much evidence indicates that prosthetic loosening has already been initiated during or shortly after the surgery, and that the subsequent progression of loosening is affected by biomechanical factors, fluid pressure fluctuations and inflammatory responses to necrotic cells and cell fragments, i.e. the concept of late loosening appears to be a misinterpretation of late-detected loosening. Clinical implications: atraumatic surgery and initial prosthetic stability are crucial in ensuring low risk of prosthetic loosening.</p>}},
author = {{Mjöberg, Bengt}},
issn = {{2396-7544}},
keywords = {{Periprosthetic osteolysis; Prosthetic loosening; Radiostereometric analysis}},
language = {{eng}},
month = {{02}},
number = {{2}},
pages = {{113--117}},
publisher = {{British Editorial Society of Bone & Joint Surgery}},
series = {{EFORT Open Reviews}},
title = {{Is early migration enough to explain late clinical loosening of hip prostheses?}},
url = {{http://dx.doi.org/10.1302/2058-5241.5.190014}},
doi = {{10.1302/2058-5241.5.190014}},
volume = {{5}},
year = {{2020}},
}