Polarization anisotropy of DNA in nanochannels
(2008) 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 p.668-670- Abstract
The local alignment of DNA stretched in nanofluidic channels is measured using polarization sensitive detection. With increased degree of stretching the polarization anisotropy increases both in the deGennes and the Odijk regime. The technique is expected to find use in studies of, for example, local conformational changes in polymer physics in confined spaces, studies of protein-DNA interactions and compactation of DNA.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1823abfd-58d8-40e0-939e-f6063270e5f8
- author
- Persson, Fredrik LU ; Westerlund, Fredrik ; Tegenfeldt, Jonas O. LU and Kristensen, Anders
- organization
- publishing date
- 2008-01-01
- type
- Contribution to conference
- publication status
- published
- keywords
- Nanofluidics, Optics, Polarization anisotropy, Polymer physics
- pages
- 3 pages
- conference name
- 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
- conference location
- San Diego, CA, United States
- conference dates
- 2008-10-12 - 2008-10-16
- external identifiers
-
- scopus:84902481724
- language
- English
- LU publication?
- yes
- id
- 1823abfd-58d8-40e0-939e-f6063270e5f8
- date added to LUP
- 2018-10-20 10:34:10
- date last changed
- 2022-01-31 06:19:35
@misc{1823abfd-58d8-40e0-939e-f6063270e5f8, abstract = {{<p>The local alignment of DNA stretched in nanofluidic channels is measured using polarization sensitive detection. With increased degree of stretching the polarization anisotropy increases both in the deGennes and the Odijk regime. The technique is expected to find use in studies of, for example, local conformational changes in polymer physics in confined spaces, studies of protein-DNA interactions and compactation of DNA.</p>}}, author = {{Persson, Fredrik and Westerlund, Fredrik and Tegenfeldt, Jonas O. and Kristensen, Anders}}, keywords = {{Nanofluidics; Optics; Polarization anisotropy; Polymer physics}}, language = {{eng}}, month = {{01}}, pages = {{668--670}}, title = {{Polarization anisotropy of DNA in nanochannels}}, year = {{2008}}, }