Stress-related challenges in pentose fermentation to ethanol by the yeast Saccharomyces cerevisiae.
(2011) In Biotechnology Journal 6. p.286-299- Abstract
- Conversion of agricultural residues, energy crops and forest residues into bioethanol requires hydrolysis of the biomass and fermentation of the released sugars. During the hydrolysis of the hemicellulose fraction, substantial amounts of pentose sugars, in particular xylose, are released. Fermentation of these pentose sugars to ethanol by engineered Saccharomyces cerevisiae under industrial process conditions is the subject of this review. First, fermentation challenges originating from the main steps of ethanol production from lignocellulosic feedstocks are discussed, followed by genetic modifications that have been implemented in S. cerevisiae to obtain xylose and arabinose fermenting capacity per se. Finally, the fermentation of a real... (More)
- Conversion of agricultural residues, energy crops and forest residues into bioethanol requires hydrolysis of the biomass and fermentation of the released sugars. During the hydrolysis of the hemicellulose fraction, substantial amounts of pentose sugars, in particular xylose, are released. Fermentation of these pentose sugars to ethanol by engineered Saccharomyces cerevisiae under industrial process conditions is the subject of this review. First, fermentation challenges originating from the main steps of ethanol production from lignocellulosic feedstocks are discussed, followed by genetic modifications that have been implemented in S. cerevisiae to obtain xylose and arabinose fermenting capacity per se. Finally, the fermentation of a real lignocellulosic medium is discussed in terms of inhibitory effects of furaldehydes, phenolics and weak acids and the presence of contaminating microbiota. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1832109
- author
- Almeida, Joao LU ; Runquist, David LU ; Sanchez Nogue, Violeta LU ; Lidén, Gunnar LU and Gorwa-Grauslund, Marie-Francoise LU
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Biotechnology Journal
- volume
- 6
- pages
- 286 - 299
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000288035100004
- pmid:21305697
- scopus:79952181277
- pmid:21305697
- ISSN
- 1860-6768
- DOI
- 10.1002/biot.201000301
- language
- English
- LU publication?
- yes
- id
- 387338a3-694a-4d44-88e4-c4277ebf504c (old id 1832109)
- date added to LUP
- 2016-04-01 11:15:41
- date last changed
- 2023-11-10 15:39:16
@article{387338a3-694a-4d44-88e4-c4277ebf504c, abstract = {{Conversion of agricultural residues, energy crops and forest residues into bioethanol requires hydrolysis of the biomass and fermentation of the released sugars. During the hydrolysis of the hemicellulose fraction, substantial amounts of pentose sugars, in particular xylose, are released. Fermentation of these pentose sugars to ethanol by engineered Saccharomyces cerevisiae under industrial process conditions is the subject of this review. First, fermentation challenges originating from the main steps of ethanol production from lignocellulosic feedstocks are discussed, followed by genetic modifications that have been implemented in S. cerevisiae to obtain xylose and arabinose fermenting capacity per se. Finally, the fermentation of a real lignocellulosic medium is discussed in terms of inhibitory effects of furaldehydes, phenolics and weak acids and the presence of contaminating microbiota.}}, author = {{Almeida, Joao and Runquist, David and Sanchez Nogue, Violeta and Lidén, Gunnar and Gorwa-Grauslund, Marie-Francoise}}, issn = {{1860-6768}}, language = {{eng}}, pages = {{286--299}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Biotechnology Journal}}, title = {{Stress-related challenges in pentose fermentation to ethanol by the yeast Saccharomyces cerevisiae.}}, url = {{http://dx.doi.org/10.1002/biot.201000301}}, doi = {{10.1002/biot.201000301}}, volume = {{6}}, year = {{2011}}, }