Technetium-99m-nanocolloid scintigraphy in orthopedic infections: a comparison with indium-111-labeled leukocytes
(1993) In Journal of Nuclear Medicine 34(10). p.1646-1650- Abstract
- Twenty-three patients with clinically suspected acute or chronic osteomyelitis and 21 patients with suspected joint prosthetic infection underwent scintigraphy using both 99mTc-nanocolloid and 111In-labeled leukocytes. The scintigrams of the two tracers were blindly interpreted by three independent observers. Their evaluations showed high correspondence. Patients were classified as having no infection, probable infection or proven infection according to specific criteria which included results of bacteriological cultures and histopathological examinations. For proven and probable infection taken together, the sensitivity with 99mTc-nanocolloid was 94%, the specificity 84% and the accuracy 87%, compared with 75%, 90% and 85% with... (More)
- Twenty-three patients with clinically suspected acute or chronic osteomyelitis and 21 patients with suspected joint prosthetic infection underwent scintigraphy using both 99mTc-nanocolloid and 111In-labeled leukocytes. The scintigrams of the two tracers were blindly interpreted by three independent observers. Their evaluations showed high correspondence. Patients were classified as having no infection, probable infection or proven infection according to specific criteria which included results of bacteriological cultures and histopathological examinations. For proven and probable infection taken together, the sensitivity with 99mTc-nanocolloid was 94%, the specificity 84% and the accuracy 87%, compared with 75%, 90% and 85% with 111In-labeled leukocytes. We conclude that 99mTc-nanocolloid scintigraphy is at least equivalent with 111In-leucocyte scintigraphy, and its additional advantages are shorter examination time, less complexity and better radiation dosimetry. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1107710
- author
- Flivik, Gunnar LU ; Sloth, Maja ; Rydholm, Urban LU ; Herrlin, Kristian and Lidgren, Lars LU
- organization
- publishing date
- 1993
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Nuclear Medicine
- volume
- 34
- issue
- 10
- pages
- 1646 - 1650
- publisher
- Society of Nuclear Medicine
- external identifiers
-
- pmid:8410276
- scopus:0027443531
- ISSN
- 0161-5505
- language
- English
- LU publication?
- yes
- id
- 185b8ba9-7fd0-42b2-9e6b-27f2ae11cd34 (old id 1107710)
- alternative location
- http://jnm.snmjournals.org/cgi/reprint/34/10/1646
- date added to LUP
- 2016-04-01 16:42:22
- date last changed
- 2021-01-03 09:22:37
@article{185b8ba9-7fd0-42b2-9e6b-27f2ae11cd34, abstract = {{Twenty-three patients with clinically suspected acute or chronic osteomyelitis and 21 patients with suspected joint prosthetic infection underwent scintigraphy using both 99mTc-nanocolloid and 111In-labeled leukocytes. The scintigrams of the two tracers were blindly interpreted by three independent observers. Their evaluations showed high correspondence. Patients were classified as having no infection, probable infection or proven infection according to specific criteria which included results of bacteriological cultures and histopathological examinations. For proven and probable infection taken together, the sensitivity with 99mTc-nanocolloid was 94%, the specificity 84% and the accuracy 87%, compared with 75%, 90% and 85% with 111In-labeled leukocytes. We conclude that 99mTc-nanocolloid scintigraphy is at least equivalent with 111In-leucocyte scintigraphy, and its additional advantages are shorter examination time, less complexity and better radiation dosimetry.}}, author = {{Flivik, Gunnar and Sloth, Maja and Rydholm, Urban and Herrlin, Kristian and Lidgren, Lars}}, issn = {{0161-5505}}, language = {{eng}}, number = {{10}}, pages = {{1646--1650}}, publisher = {{Society of Nuclear Medicine}}, series = {{Journal of Nuclear Medicine}}, title = {{Technetium-99m-nanocolloid scintigraphy in orthopedic infections: a comparison with indium-111-labeled leukocytes}}, url = {{http://jnm.snmjournals.org/cgi/reprint/34/10/1646}}, volume = {{34}}, year = {{1993}}, }