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Simple model for the growth behaviour of mixed lecithin-bile salt micelles

Madenci, Dilek; Salonen, Anniina; Schurtenberger, Peter LU ; Pedersen, Jan Skov and Egelhaaf, Stefan U. (2011) In Physical Chemistry Chemical Physics 13(8). p.3171-3178
Abstract
Mixed lecithin-bile salt micelles are known to have a cylindrical or worm-like structure. We investigated their shape, length, flexibility and cross-sectional structure using small-angle neutron scattering (SANS). A broad range of sample compositions was studied varying both the total amphiphile concentration and the molar ratio of bile salt (sodium taurochenodeoxycholate, NaTCDC) to lecithin (egg yolk phosphatidylcholine, EYL). The length of the micelles was quantitatively linked to the micellar composition by introducing a simple model. The model takes into account the partitioning of lecithin and bile salt between the bulk, cylindrical parts and the end caps of the micelles. The model also sheds light on the organization of the... (More)
Mixed lecithin-bile salt micelles are known to have a cylindrical or worm-like structure. We investigated their shape, length, flexibility and cross-sectional structure using small-angle neutron scattering (SANS). A broad range of sample compositions was studied varying both the total amphiphile concentration and the molar ratio of bile salt (sodium taurochenodeoxycholate, NaTCDC) to lecithin (egg yolk phosphatidylcholine, EYL). The length of the micelles was quantitatively linked to the micellar composition by introducing a simple model. The model takes into account the partitioning of lecithin and bile salt between the bulk, cylindrical parts and the end caps of the micelles. The model also sheds light on the organization of the micelles, both in their cylindrical regions and end caps. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Physical Chemistry Chemical Physics
volume
13
issue
8
pages
3171 - 3178
publisher
Royal Society of Chemistry
external identifiers
  • wos:000287041700020
  • scopus:79951497644
ISSN
1463-9084
DOI
10.1039/c0cp01700k
language
English
LU publication?
yes
id
3d0f9c23-d900-4e9a-97b8-fe184f2ee4c7 (old id 1872531)
date added to LUP
2011-04-20 10:03:48
date last changed
2017-09-10 04:15:18
@article{3d0f9c23-d900-4e9a-97b8-fe184f2ee4c7,
  abstract     = {Mixed lecithin-bile salt micelles are known to have a cylindrical or worm-like structure. We investigated their shape, length, flexibility and cross-sectional structure using small-angle neutron scattering (SANS). A broad range of sample compositions was studied varying both the total amphiphile concentration and the molar ratio of bile salt (sodium taurochenodeoxycholate, NaTCDC) to lecithin (egg yolk phosphatidylcholine, EYL). The length of the micelles was quantitatively linked to the micellar composition by introducing a simple model. The model takes into account the partitioning of lecithin and bile salt between the bulk, cylindrical parts and the end caps of the micelles. The model also sheds light on the organization of the micelles, both in their cylindrical regions and end caps.},
  author       = {Madenci, Dilek and Salonen, Anniina and Schurtenberger, Peter and Pedersen, Jan Skov and Egelhaaf, Stefan U.},
  issn         = {1463-9084},
  language     = {eng},
  number       = {8},
  pages        = {3171--3178},
  publisher    = {Royal Society of Chemistry},
  series       = {Physical Chemistry Chemical Physics},
  title        = {Simple model for the growth behaviour of mixed lecithin-bile salt micelles},
  url          = {http://dx.doi.org/10.1039/c0cp01700k},
  volume       = {13},
  year         = {2011},
}