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P57Kip2regulates T-cell development and lymphoma

Jayapal, Senthil Raja and Kaldis, Philipp LU orcid (2014) In Blood 123(22). p.3370-3371
Abstract

In this issue of Blood, Matsumoto et al report that T cell-specific deletion of the cyclin-dependent kinase inhibitor p57Kip2(p57) in mice leads to a block in T-cell development as a result of hyperactivation of the E2F-p53 pathway and demonstrate that the loss of p57 accelerates lymphomagenesis in the absence of p53.

Please use this url to cite or link to this publication:
author
and
publishing date
type
Contribution to journal
publication status
published
in
Blood
volume
123
issue
22
pages
3370 - 3371
publisher
American Society of Hematology
external identifiers
  • pmid:24876523
  • scopus:84901699631
ISSN
0006-4971
DOI
10.1182/blood-2014-04-565309
language
English
LU publication?
no
id
190df657-a11d-42fa-b661-ae00ed9cc991
date added to LUP
2019-09-18 13:54:45
date last changed
2024-01-01 20:29:07
@article{190df657-a11d-42fa-b661-ae00ed9cc991,
  abstract     = {{<p>In this issue of Blood, Matsumoto et al report that T cell-specific deletion of the cyclin-dependent kinase inhibitor p57<sup>Kip2</sup>(p57) in mice leads to a block in T-cell development as a result of hyperactivation of the E2F-p53 pathway and demonstrate that the loss of p57 accelerates lymphomagenesis in the absence of p53.</p>}},
  author       = {{Jayapal, Senthil Raja and Kaldis, Philipp}},
  issn         = {{0006-4971}},
  language     = {{eng}},
  month        = {{05}},
  number       = {{22}},
  pages        = {{3370--3371}},
  publisher    = {{American Society of Hematology}},
  series       = {{Blood}},
  title        = {{P57<sup>Kip2</sup>regulates T-cell development and lymphoma}},
  url          = {{http://dx.doi.org/10.1182/blood-2014-04-565309}},
  doi          = {{10.1182/blood-2014-04-565309}},
  volume       = {{123}},
  year         = {{2014}},
}