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Effects of Weak Environmental Magnetic Fields on the Spontaneous Bioelectrical Activity of Snail Neurons

Kaviani Moghadam, Mehri LU ; Firoozabadi, Mohammad and Janahmadi, Mahyar (2011) In Journal of Membrane Biology 240(2). p.63-71
Abstract
We examined the effects of 50-Hz magnetic fields in the range of flux densities relevant to our current environmental exposures on action potential (AP), after-hyperpolarization potential (AHP) and neuronal excitability in neurons of land snails, Helix aspersa. It was shown that when the neurons were exposed to magnetic field at the various flux densities, marked changes in neuronal excitability, AP firing frequency and AHP amplitude were seen. These effects seemed to be related to the intensity, type (single and continuous or repeated and cumulative) and length of exposure (18 or 20 min). The extremely low-frequency (ELF) magnetic field exposures affect the excitability of F1 neuronal cells in a nonmonotonic manner, disrupting their... (More)
We examined the effects of 50-Hz magnetic fields in the range of flux densities relevant to our current environmental exposures on action potential (AP), after-hyperpolarization potential (AHP) and neuronal excitability in neurons of land snails, Helix aspersa. It was shown that when the neurons were exposed to magnetic field at the various flux densities, marked changes in neuronal excitability, AP firing frequency and AHP amplitude were seen. These effects seemed to be related to the intensity, type (single and continuous or repeated and cumulative) and length of exposure (18 or 20 min). The extremely low-frequency (ELF) magnetic field exposures affect the excitability of F1 neuronal cells in a nonmonotonic manner, disrupting their normal characteristic and synchronized firing patterns by interfering with the cell membrane electrophysiological properties. Our results could explain one of the mechanisms and sites of action of ELF magnetic fields. A possible explanation of the inhibitory effects of magnetic fields could be a decrease in Ca2+ influx through inhibition of voltage-gated Ca2+ channels. The detailed mechanism of effect, however, needs to be further studied under voltage-clamp conditions. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Extremely low-frequency magnetic field, Membrane potential, Helix, aspersa, Neuronal excitability
in
Journal of Membrane Biology
volume
240
issue
2
pages
63 - 71
publisher
Springer
external identifiers
  • wos:000288547700001
  • scopus:79953676263
ISSN
0022-2631
DOI
10.1007/s00232-011-9344-z
language
English
LU publication?
yes
id
d4e00a56-a16c-448f-9868-6723c14046c9 (old id 1925830)
date added to LUP
2011-05-11 08:24:55
date last changed
2017-08-20 03:51:28
@article{d4e00a56-a16c-448f-9868-6723c14046c9,
  abstract     = {We examined the effects of 50-Hz magnetic fields in the range of flux densities relevant to our current environmental exposures on action potential (AP), after-hyperpolarization potential (AHP) and neuronal excitability in neurons of land snails, Helix aspersa. It was shown that when the neurons were exposed to magnetic field at the various flux densities, marked changes in neuronal excitability, AP firing frequency and AHP amplitude were seen. These effects seemed to be related to the intensity, type (single and continuous or repeated and cumulative) and length of exposure (18 or 20 min). The extremely low-frequency (ELF) magnetic field exposures affect the excitability of F1 neuronal cells in a nonmonotonic manner, disrupting their normal characteristic and synchronized firing patterns by interfering with the cell membrane electrophysiological properties. Our results could explain one of the mechanisms and sites of action of ELF magnetic fields. A possible explanation of the inhibitory effects of magnetic fields could be a decrease in Ca2+ influx through inhibition of voltage-gated Ca2+ channels. The detailed mechanism of effect, however, needs to be further studied under voltage-clamp conditions.},
  author       = {Kaviani Moghadam, Mehri and Firoozabadi, Mohammad and Janahmadi, Mahyar},
  issn         = {0022-2631},
  keyword      = {Extremely low-frequency magnetic field,Membrane potential,Helix,aspersa,Neuronal excitability},
  language     = {eng},
  number       = {2},
  pages        = {63--71},
  publisher    = {Springer},
  series       = {Journal of Membrane Biology},
  title        = {Effects of Weak Environmental Magnetic Fields on the Spontaneous Bioelectrical Activity of Snail Neurons},
  url          = {http://dx.doi.org/10.1007/s00232-011-9344-z},
  volume       = {240},
  year         = {2011},
}