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Variety in vegetable and fruit consumption and risk of bladder cancer in the European Prospective Investigation into Cancer and Nutrition

Buchner, Frederike L.; Bueno-de-Mesquita, H. Bas; Ros, Martine M.; Kampman, Ellen; Egevad, Lars; Overvad, Kim; Tjonneland, Anne; Roswall, Nina; Clavel-Chapelon, Francoise and Boutron-Ruault, Marie-Christine, et al. (2011) In International Journal of Cancer 128(12). p.2971-2979
Abstract
Recent research does not show an association between fruit and vegetable consumption and bladder cancer risk. None of these studies investigated variety in fruit and vegetable consumption, which may capture different aspects of consumption. We investigated whether a varied consumption of vegetables and fruits is associated with bladder cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Detailed data on food consumption and complete follow-up for cancer incidence were available for 452,185 participants, who were recruited from ten European countries. After a mean follow-up of 8.7 years, 874 participants were diagnosed with bladder cancer. Diet diversity scores (DDSs) were used to quantify the... (More)
Recent research does not show an association between fruit and vegetable consumption and bladder cancer risk. None of these studies investigated variety in fruit and vegetable consumption, which may capture different aspects of consumption. We investigated whether a varied consumption of vegetables and fruits is associated with bladder cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Detailed data on food consumption and complete follow-up for cancer incidence were available for 452,185 participants, who were recruited from ten European countries. After a mean follow-up of 8.7 years, 874 participants were diagnosed with bladder cancer. Diet diversity scores (DDSs) were used to quantify the variety in fruit and vegetable consumption. Multivariable Cox proportional hazard models were used to assess the effect of the DDSs on bladder cancer risk. There was no evidence of a statistically significant association between bladder cancer risk and any of the DDSs when these scores were considered as continuous covariates. However, the hazard ratio (HR) for the highest tertile of the DDS for combined fruit and vegetable consumption was marginally significant compared to the lowest (HR = 1.30, 95% confidence interval: 1.00-1.69, p-trend = 0.05). In EPIC, there is no clear association between a varied fruit and vegetable consumption and bladder cancer risk. This finding provides further evidence for the absence of any strong association between fruit and vegetable consumption as measured by a food frequency questionnaire and bladder cancer risk. (Less)
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publication status
published
subject
keywords
bladder cancer, DDS, fruit, vegetables, EPIC
in
International Journal of Cancer
volume
128
issue
12
pages
2971 - 2979
publisher
John Wiley & Sons
external identifiers
  • wos:000289986900023
  • scopus:79955377003
ISSN
0020-7136
DOI
10.1002/ijc.25636
language
English
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yes
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6cb7811d-f32b-4080-8bcb-bc9c6f141e28 (old id 1964382)
date added to LUP
2011-06-01 10:37:32
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2017-08-06 03:19:14
@article{6cb7811d-f32b-4080-8bcb-bc9c6f141e28,
  abstract     = {Recent research does not show an association between fruit and vegetable consumption and bladder cancer risk. None of these studies investigated variety in fruit and vegetable consumption, which may capture different aspects of consumption. We investigated whether a varied consumption of vegetables and fruits is associated with bladder cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Detailed data on food consumption and complete follow-up for cancer incidence were available for 452,185 participants, who were recruited from ten European countries. After a mean follow-up of 8.7 years, 874 participants were diagnosed with bladder cancer. Diet diversity scores (DDSs) were used to quantify the variety in fruit and vegetable consumption. Multivariable Cox proportional hazard models were used to assess the effect of the DDSs on bladder cancer risk. There was no evidence of a statistically significant association between bladder cancer risk and any of the DDSs when these scores were considered as continuous covariates. However, the hazard ratio (HR) for the highest tertile of the DDS for combined fruit and vegetable consumption was marginally significant compared to the lowest (HR = 1.30, 95% confidence interval: 1.00-1.69, p-trend = 0.05). In EPIC, there is no clear association between a varied fruit and vegetable consumption and bladder cancer risk. This finding provides further evidence for the absence of any strong association between fruit and vegetable consumption as measured by a food frequency questionnaire and bladder cancer risk.},
  author       = {Buchner, Frederike L. and Bueno-de-Mesquita, H. Bas and Ros, Martine M. and Kampman, Ellen and Egevad, Lars and Overvad, Kim and Tjonneland, Anne and Roswall, Nina and Clavel-Chapelon, Francoise and Boutron-Ruault, Marie-Christine and Touillaud, Marina and Kaaks, Rudolf and Chang-Claude, Jenny and Boeing, Heiner and Weikert, Steffen and Trichopoulou, Antonia and Naska, Ada and Benetou, Vicky and Palli, Domenico and Sieri, Sabina and Vineis, Paolo and Tumino, Rosario and Panico, Salvatore and van Duijnhoven, Franzel J. B. and Peeters, Petra H. M. and van Gils, Carla H. and Lund, Eiliv and Gram, Inger T. and Sanchez, Maria-Jose and Jakszyn, Paula and Larranaga, Nerea and Ardanaz, Eva and Navarro, Carmen and Rodriguez, Laudina and Manjer, Jonas and Ehrnström, Roy and Hallmans, Goran and Ljungberg, Borje and Key, Tim J. and Allen, Naomi E. and Khaw, Kay-Tee and Wareham, Nicholas and Slimani, Nadia and Jenab, Mazda and Boffetta, Paolo and Kiemeney, Lambertus A. L. M. and Riboli, Elio},
  issn         = {0020-7136},
  keyword      = {bladder cancer,DDS,fruit,vegetables,EPIC},
  language     = {eng},
  number       = {12},
  pages        = {2971--2979},
  publisher    = {John Wiley & Sons},
  series       = {International Journal of Cancer},
  title        = {Variety in vegetable and fruit consumption and risk of bladder cancer in the European Prospective Investigation into Cancer and Nutrition},
  url          = {http://dx.doi.org/10.1002/ijc.25636},
  volume       = {128},
  year         = {2011},
}