Advanced

Health-related quality of life is impaired in active collagenous colitis

Hjortswang, Henrik; Tysk, Curt; Bohr, Johan; Benoni, Cecilia LU ; Vigren, Lina LU ; Kilander, Anders; Larsson, Lasse; Taha, Yesuf and Strom, Magnus (2011) In Digestive and Liver Disease 43(2). p.102-109
Abstract
Objectives: The characteristic clinical symptoms of collagenous colitis are non-bloody diarrhoea, urgency and abdominal pain. Treatment is aimed at reducing the symptom burden and the disease impact on patients' health-related quality of life. The objective of this study was to analyse health-related quality of life in patients with collagenous colitis. Methods: In a cross-sectional, postal HRQL survey, 116 patients with collagenous colitis at four Swedish hospitals completed four health-related quality of life questionnaires, two disease-specific (Inflammatory Bowel Disease Questionnaire and Rating Form of IBD Patient Concerns), and two generic (Short Form 36, SF-36, and Psychological General Well-Being, PGWB), and a one-week symptom... (More)
Objectives: The characteristic clinical symptoms of collagenous colitis are non-bloody diarrhoea, urgency and abdominal pain. Treatment is aimed at reducing the symptom burden and the disease impact on patients' health-related quality of life. The objective of this study was to analyse health-related quality of life in patients with collagenous colitis. Methods: In a cross-sectional, postal HRQL survey, 116 patients with collagenous colitis at four Swedish hospitals completed four health-related quality of life questionnaires, two disease-specific (Inflammatory Bowel Disease Questionnaire and Rating Form of IBD Patient Concerns), and two generic (Short Form 36, SF-36, and Psychological General Well-Being, PGWB), and a one-week symptom diary. Demographic and disease-related data were collected. Results for the collagenous colitis population were compared with a background population controlled for age and gender (n = 8931). Results: Compared with a Swedish background population, patients with collagenous colitis scored significantly worse in all Short Form 36 dimensions (p < 0.01), except physical function. Patients with active disease scored worse health-related quality of life than patients in remission. Co-existing disease had an impact on health-related quality of life measured with the generic measures. Lower education level and shorter disease duration were associated with decreased well-being. Conclusion: Health-related quality of life was impaired in patients with collagenous colitis compared with a background population. Disease activity is the most important factor associated with impairment of health-related quality of life. Patients in remission have a health-related quality of life similar to a background population. (C) 2010 Published by Elsevier Ltd on behalf of Editrice Gastroenterologica Italiana S.r.l. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Collagenous colitis, Health, Health-related quality of life, Inflammatory bowel disease (IBD), Microscopic colitis, Quality of life
in
Digestive and Liver Disease
volume
43
issue
2
pages
102 - 109
publisher
Elsevier
external identifiers
  • wos:000290008100004
  • scopus:78651413985
ISSN
1590-8658
DOI
10.1016/j.dld.2010.06.004
language
English
LU publication?
yes
id
d52213eb-72db-4934-a66c-6daeaceaa14d (old id 1964516)
date added to LUP
2011-06-01 10:38:20
date last changed
2017-10-01 03:27:35
@article{d52213eb-72db-4934-a66c-6daeaceaa14d,
  abstract     = {Objectives: The characteristic clinical symptoms of collagenous colitis are non-bloody diarrhoea, urgency and abdominal pain. Treatment is aimed at reducing the symptom burden and the disease impact on patients' health-related quality of life. The objective of this study was to analyse health-related quality of life in patients with collagenous colitis. Methods: In a cross-sectional, postal HRQL survey, 116 patients with collagenous colitis at four Swedish hospitals completed four health-related quality of life questionnaires, two disease-specific (Inflammatory Bowel Disease Questionnaire and Rating Form of IBD Patient Concerns), and two generic (Short Form 36, SF-36, and Psychological General Well-Being, PGWB), and a one-week symptom diary. Demographic and disease-related data were collected. Results for the collagenous colitis population were compared with a background population controlled for age and gender (n = 8931). Results: Compared with a Swedish background population, patients with collagenous colitis scored significantly worse in all Short Form 36 dimensions (p &lt; 0.01), except physical function. Patients with active disease scored worse health-related quality of life than patients in remission. Co-existing disease had an impact on health-related quality of life measured with the generic measures. Lower education level and shorter disease duration were associated with decreased well-being. Conclusion: Health-related quality of life was impaired in patients with collagenous colitis compared with a background population. Disease activity is the most important factor associated with impairment of health-related quality of life. Patients in remission have a health-related quality of life similar to a background population. (C) 2010 Published by Elsevier Ltd on behalf of Editrice Gastroenterologica Italiana S.r.l.},
  author       = {Hjortswang, Henrik and Tysk, Curt and Bohr, Johan and Benoni, Cecilia and Vigren, Lina and Kilander, Anders and Larsson, Lasse and Taha, Yesuf and Strom, Magnus},
  issn         = {1590-8658},
  keyword      = {Collagenous colitis,Health,Health-related quality of life,Inflammatory bowel disease (IBD),Microscopic colitis,Quality of life},
  language     = {eng},
  number       = {2},
  pages        = {102--109},
  publisher    = {Elsevier},
  series       = {Digestive and Liver Disease},
  title        = {Health-related quality of life is impaired in active collagenous colitis},
  url          = {http://dx.doi.org/10.1016/j.dld.2010.06.004},
  volume       = {43},
  year         = {2011},
}