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Metabolic and functional phenotypic profiling of Drosophila melanogaster reveals reduced sex differentiation under stressful environmental conditions

Ørsted, Michael; Malmendal, Anders LU ; Muñoz, Joaquin and Kristensen, Torsten Nygaard (2018) In Biological Journal of the Linnean Society 123(1). p.155-162
Abstract

Strong sexual dimorphism is commonly observed across species and, e.g., trade-offs between reproduction and maintenance are thought to explain this dimorphism. Here we test how the metabolic and functional phenotypic responses to varying types of environmental stress differ in male and female Drosophila melanogaster (Diptera: Drosophilidae), and how stress impacts the magnitude of sexual dimorphism. Experimental stressors that we exposed flies to during development were heat stress, poor nutrition, high acidity, high levels of ammonia and ethanol. Emerged male and female flies from the different rearing regimes were investigated using nuclear magnetic resonance (NMR) metabolomics and assessed for body mass and viability. Our results... (More)

Strong sexual dimorphism is commonly observed across species and, e.g., trade-offs between reproduction and maintenance are thought to explain this dimorphism. Here we test how the metabolic and functional phenotypic responses to varying types of environmental stress differ in male and female Drosophila melanogaster (Diptera: Drosophilidae), and how stress impacts the magnitude of sexual dimorphism. Experimental stressors that we exposed flies to during development were heat stress, poor nutrition, high acidity, high levels of ammonia and ethanol. Emerged male and female flies from the different rearing regimes were investigated using nuclear magnetic resonance (NMR) metabolomics and assessed for body mass and viability. Our results showed that environmental stress leads to reduced sexual dimorphism in both metabolic composition and body mass compared to the level of dimorphism observed at benign conditions. This reduced sexual dimorphism in stressful environments might be caused by a lower investment in sex-specific characteristics under such conditions, and our results provide support for the longstanding idea that ecological factors are important for shaping sexual dimorphism and possibly sexual selection.

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organization
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type
Contribution to journal
publication status
published
subject
keywords
Drosophila melanogaster, Environmental stress, Functional phenotypes, NMR metabolomics, Sex differentiation
in
Biological Journal of the Linnean Society
volume
123
issue
1
pages
8 pages
publisher
Linnean Society of London
external identifiers
  • scopus:85040634667
ISSN
0024-4066
DOI
language
English
LU publication?
yes
id
19943074-cfa5-45ce-a47b-3f42817374a3
date added to LUP
2018-01-30 14:50:50
date last changed
2018-05-29 09:48:30
@article{19943074-cfa5-45ce-a47b-3f42817374a3,
  abstract     = {<p>Strong sexual dimorphism is commonly observed across species and, e.g., trade-offs between reproduction and maintenance are thought to explain this dimorphism. Here we test how the metabolic and functional phenotypic responses to varying types of environmental stress differ in male and female Drosophila melanogaster (Diptera: Drosophilidae), and how stress impacts the magnitude of sexual dimorphism. Experimental stressors that we exposed flies to during development were heat stress, poor nutrition, high acidity, high levels of ammonia and ethanol. Emerged male and female flies from the different rearing regimes were investigated using nuclear magnetic resonance (NMR) metabolomics and assessed for body mass and viability. Our results showed that environmental stress leads to reduced sexual dimorphism in both metabolic composition and body mass compared to the level of dimorphism observed at benign conditions. This reduced sexual dimorphism in stressful environments might be caused by a lower investment in sex-specific characteristics under such conditions, and our results provide support for the longstanding idea that ecological factors are important for shaping sexual dimorphism and possibly sexual selection.</p>},
  articleno    = {blx120},
  author       = {Ørsted, Michael and Malmendal, Anders and Muñoz, Joaquin and Kristensen, Torsten Nygaard},
  issn         = {0024-4066},
  keyword      = {Drosophila melanogaster,Environmental stress,Functional phenotypes,NMR metabolomics,Sex differentiation},
  language     = {eng},
  month        = {01},
  number       = {1},
  pages        = {155--162},
  publisher    = {Linnean Society of London},
  series       = {Biological Journal of the Linnean Society},
  title        = {Metabolic and functional phenotypic profiling of Drosophila melanogaster reveals reduced sex differentiation under stressful environmental conditions},
  url          = {http://dx.doi.org/},
  volume       = {123},
  year         = {2018},
}