Treatment of age-related macular degeneration after cataract surgery : a study from the Swedish National Cataract and Macula Registers
(2021) In Acta Ophthalmologica 99(1).- Abstract
Purpose: To characterize pre- and perioperative factors associated with treatment for wet age-related macular degeneration (wet AMD) after cataract surgery. Methods: This register-based cohort study with data from the Swedish National Cataract Register (NCR) and the Swedish Macula Register (SMR) from 2010 to 2017 compared eyes with and without preoperative AMD that had undergone cataract surgery and was subsequently treated for wet AMD to eyes not treated within the study period. All first-eye surgeries registered in the NCR from 2010 to 2017 and matching eyes found in the SMR that had undergone treatment for wet AMD ≥ 1 year after the cataract procedure were included. Data for cataract surgery date, age and gender, use of a... (More)
Purpose: To characterize pre- and perioperative factors associated with treatment for wet age-related macular degeneration (wet AMD) after cataract surgery. Methods: This register-based cohort study with data from the Swedish National Cataract Register (NCR) and the Swedish Macula Register (SMR) from 2010 to 2017 compared eyes with and without preoperative AMD that had undergone cataract surgery and was subsequently treated for wet AMD to eyes not treated within the study period. All first-eye surgeries registered in the NCR from 2010 to 2017 and matching eyes found in the SMR that had undergone treatment for wet AMD ≥ 1 year after the cataract procedure were included. Data for cataract surgery date, age and gender, use of a blue-blocking IOL, preoperative visual acuity, ocular comorbidities, posterior capsule rupture and date of AMD treatment initiation were extracted. Results: The only independent factor associated with postoperative treatment of wet AMD in both groups was female gender (67.3% vs. 58.8%, p < 0.001 and 66.4% vs. 60.6%, p = 0.001, respectively). Older age was an independent factor in eyes without preoperative AMD (78.4 ± 6.5 vs. 73.4 ± 9.6 years, p < 0.001). A blue-blocking IOL appeared to decrease the likelihood of subsequent wet AMD treatment slightly but not statistically significant in eyes with preoperative AMD (52.7% vs. 56.8%, p = 0.110). Conclusions: Some factors (female gender, high age) are associated with undergoing subsequent treatment for wet AMD to a higher extent. If the use of a blue-blocking IOL offers any protection from undergoing AMD treatment after cataract surgery, such an effect must be very small.
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- author
- Westborg, Inger ; Albrecht, Susanne ; Granstam, Elisabet ; Karlsson, Niklas ; Kugelberg, Maria ; Lundström, Mats LU ; Montan, Per and Behndig, Anders
- organization
- publishing date
- 2021
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- age-related macular degeneration, blue-blocking IOLs, cataract surgery, register-based cohort study
- in
- Acta Ophthalmologica
- volume
- 99
- issue
- 1
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85087159298
- pmid:32573070
- ISSN
- 1755-375X
- DOI
- 10.1111/aos.14519
- language
- English
- LU publication?
- yes
- id
- 19caf750-7dc6-4f9e-b957-c1f65d52c960
- date added to LUP
- 2020-07-20 09:42:31
- date last changed
- 2024-06-12 17:33:41
@article{19caf750-7dc6-4f9e-b957-c1f65d52c960,
abstract = {{<p>Purpose: To characterize pre- and perioperative factors associated with treatment for wet age-related macular degeneration (wet AMD) after cataract surgery. Methods: This register-based cohort study with data from the Swedish National Cataract Register (NCR) and the Swedish Macula Register (SMR) from 2010 to 2017 compared eyes with and without preoperative AMD that had undergone cataract surgery and was subsequently treated for wet AMD to eyes not treated within the study period. All first-eye surgeries registered in the NCR from 2010 to 2017 and matching eyes found in the SMR that had undergone treatment for wet AMD ≥ 1 year after the cataract procedure were included. Data for cataract surgery date, age and gender, use of a blue-blocking IOL, preoperative visual acuity, ocular comorbidities, posterior capsule rupture and date of AMD treatment initiation were extracted. Results: The only independent factor associated with postoperative treatment of wet AMD in both groups was female gender (67.3% vs. 58.8%, p < 0.001 and 66.4% vs. 60.6%, p = 0.001, respectively). Older age was an independent factor in eyes without preoperative AMD (78.4 ± 6.5 vs. 73.4 ± 9.6 years, p < 0.001). A blue-blocking IOL appeared to decrease the likelihood of subsequent wet AMD treatment slightly but not statistically significant in eyes with preoperative AMD (52.7% vs. 56.8%, p = 0.110). Conclusions: Some factors (female gender, high age) are associated with undergoing subsequent treatment for wet AMD to a higher extent. If the use of a blue-blocking IOL offers any protection from undergoing AMD treatment after cataract surgery, such an effect must be very small.</p>}},
author = {{Westborg, Inger and Albrecht, Susanne and Granstam, Elisabet and Karlsson, Niklas and Kugelberg, Maria and Lundström, Mats and Montan, Per and Behndig, Anders}},
issn = {{1755-375X}},
keywords = {{age-related macular degeneration; blue-blocking IOLs; cataract surgery; register-based cohort study}},
language = {{eng}},
number = {{1}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Ophthalmologica}},
title = {{Treatment of age-related macular degeneration after cataract surgery : a study from the Swedish National Cataract and Macula Registers}},
url = {{http://dx.doi.org/10.1111/aos.14519}},
doi = {{10.1111/aos.14519}},
volume = {{99}},
year = {{2021}},
}